Prevalence, histopathological findings and aerobic bacteria flora associated with pneumopathies in goats slaughtered at the Nsukka abattoir

This study was conducted to determine the prevalence, histopathological findings and aerobic bacteria flora associated with pneumopathies in goats slaughtered for human consumption at the Nsukka abattoir. The lungs of 342 goats were examined for gross lesions and samples were collected for histopathological and bacteriological examinations. Microscopic findings of this study showed that a total of 136 (39.8%) of the samples had various types of pneumopathies including bronchopneumonia, interstitial pneumonia, hyperemia, haemorrhages, oedema, etc. Bronchopneumonia was observed in 54 (39.70%) of the 136 lungs with pneumopathies while interstitial pneumonia and non-pneumonic pneumopathies were recorded in 44 (32.35%) and 38 (27.94%) respectively. Seventy-nine (58.11%) out of the examined 136, were recorded during the wet season and 57 (41.9%) in the dry season. Ninety-six (70.6%) of the cases were found in Kano brown goats, 39(28.67%) in West African dwarf goats and 1(0.73%) in Sahel goats. More of the females examined had pneumopathies. Aerobic bacteria isolated from the lungs with pneumopathies were E. coli, Klebsiella pneumoniae, Mannheimia haemolytica, Streptococcus pyogenes, Staphylococcus aureus, Bacillus subtilis, Proteus vulgaris and Pasteurella multocida. E. coli with a prevalence rate of 73.5% was the most predominant isolate. There was no significant association between the lung lesions observed and the associated aerobic bacterial isolates, seasons, sexes and breeds.Keywords: Aerobic bacteria isolates, Bronchopneumonia, Interstitial pneumonia, Pneumopathies, prevalenc

High Lassa Fever activity in Northern part of Edo State, Nigeria: reanalysis of con\ufb01rmatory test results

The purpose was to establish simple statistics of the e\ufb00ects of lassa fever in northern part of Edo State, Nigeria. Lassa fever activity in the northern part of Edo state, Nigeria, was con\ufb01rmed in 2004 by laboratory analysis of samples sent to Bernhard\u2013Nocht Institute (BNI) for Tropical Medicine Hamburg, Germany. The published report of that study is re-analysed to determine in statistical terms, what the values presented in percentages translate to in number of persons in the hospital and the area. In the year 2004, 12,000 persons presented with febrile illness at Irrua Specialist Teaching Hospital (ISTH), Irrua; 832 (6.5%) had lassa fever con\ufb01rmed by reversetranscriptase-polymerase chain reaction (RT-PCR). 4,096 (32.26%) of those with febrile illness had acute infection as they tested positive for IgM antibody. 333 (33.33%) of about 1000 sta\ufb00 of the hospital had sub-clinical infection as they tested positive for IgG and negative for IgM antibody. At least 208 of the 832 patients (25%) of the hospital with con\ufb01rmed lassa fever must have died in the year 2004. 967 (5.9%) of relatives or members of the public who had contact with infected persons had con\ufb01rmed lassa fever. 555 (66.67%) of those with con\ufb01rmed lassa fever are close relatives. The epidemics occur in clusters of households, houses, streets or villages. It is concluded that high lassa fever activity in the area has wider e\ufb00ects than what is observed in hospital admitted patients. Further seroepidemiological survey involving large population sample in the area should be carried out to establish more accurate seroepidemiological data on lassa fever. This study is expected to impact positively on the generation of political priority for the control of lassa fever in Nigeri

High Lassa Fever activity in Northern part of Edo State, Nigeria: reanalysis of confirmatory test results

The purpose was to establish simple statistics of the effects of lassa fever in northern part of Edo State, Nigeria. Lassa fever activity in the northern part of Edo state, Nigeria, was confirmed in 2004 by laboratory analysis of samples sent to Bernhard–Nocht Institute (BNI) for Tropical Medicine Hamburg, Germany. The published report of that study is re-analysed to determine in statistical terms, what the values presented in percentages translate to in number of persons in the hospital and the area. In the year 2004, 12,000 persons presented with febrile illness at Irrua Specialist Teaching Hospital (ISTH), Irrua; 832 (6.5%) had lassa fever confirmed by reversetranscriptase-polymerase chain reaction (RT-PCR). 4,096 (32.26%) of those with febrile illness had acute infection as they tested positive for IgM antibody. 333 (33.33%) of about 1000 staff of the hospital had sub-clinical infection as they tested positive for IgG and negative for IgM antibody. At least 208 of the 832 patients (25%) of the hospital with confirmed lassa fever must have died in the year 2004. 967 (5.9%) of relatives or members of the public who had contact with infected persons had confirmed lassa fever. 555 (66.67%) of those with confirmed lassa fever are close relatives. The epidemics occur in clusters of households, houses, streets or villages. It is concluded that high lassa fever activity in the area has wider effects than what is observed in hospital admitted patients. Further seroepidemiological survey involving large population sample in the area should be carried out to establish more accurate seroepidemiological data on lassa fever. This study is expected to impact positively on the generation of political priority for the control of lassa fever in Nigeri