34 research outputs found
Non-Kaehler Heterotic String Compactifications with non-zero fluxes and constant dilaton
We construct new explicit compact supersymmetric valid solutions with
non-zero field strength, non-flat instanton and constant dilaton to the
heterotic equations of motion in dimension six. We present balanced Hermitian
structures on compact nilmanifolds in dimension six satisfying the heterotic
supersymmetry equations with non-zero flux, non-flat instanton and constant
dilaton which obey the three-form Bianchi identity with curvature term taken
with respect to either the Levi-Civita, the (+)-connection or the Chern
connection. Among them, all our solutions with respect to the (+)-connection on
the compact nilmanifold satisfy the heterotic equations of motion.Comment: LaTeX, 16 pp., no figures, new Theorem 1.1, references adde
Bolivia potato germplasm collecting expeditions 1993 and 1994: taxonomy and new germplasm resources
We conducted joint Bolivia/The Netherlands/United States wild potato (Solanum sect. Petota Dumort.) germplasm collecting expeditions in Bolivia from February 1-April 15, 1993, and January 1-February 26, 1994. The goals of the expeditions were to collect germplasm and gather data for continuing taxonomic studies of the approximately 43 taxa of Bolivian wild potatoes accepted by current taxonomists. We made 223 collections, 135 as true seed collections, 54 as tubers, 19 only as herbarium collections. Two recent taxonomic treatments of Bolivian wild and cultivated potatoes have clarified the taxonomy and distribution of these plants, but there are continuing disagreements between treatments regarding species boundaries and interrelationships. These disagreements, and the variability we observed in natural populations, present problems for identifications. We summarize the state of germplasm collections for Bolivia, provide our field data regarding the taxonomy of Bolivian wild potatoes, provide recommendations for future collecting, and provide new chromosome counts for S. hoopesii, S. ugentii, and S. yungasense
XRCC1 polymorphisms and haplotypes in Mexican patients with acute lymphoblastic leukemia
We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphisms of XRCC1 (X-ray repair cross-complementing group 1) on the development of childhood acute lymphoblastic leukemia (ALL) in 120 ALL patients and 120 controls in Mexico. All of them were genotyped for these polymorphisms, using polymerase chain reaction. No significant differences in allele and genotype frequencies for any polymorphism were observed between patients and controls. Estimation of haplotypes showed the eight expected haplotypes (A-H), seven of which were found in both patients and controls; haplotype A (Arg-Arg-Arg) was the most common, whereas haplotypes F and G were absent in patients and controls, respectively. Haplotype B (Trp-Arg-Arg) was found to be associated with an increased risk of ALL (odds ratio (OR) = 1.95, 95% confidence interval (CI) = 1.13-3.37; P = 0.016), particularly in males (OR = 2.65, 95%CI = 1.25-5.63; P = 0.01). Individually, the 194Trp, 280His, and 399Gln alleles were not associated with significantly increased risk for ALL in these Mexican children. �FUNPEC-RP
Alternative contemporary group structure to maximize the use of field records: Application to growth traits of composite beef cattle
MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer.
DNA repair proteins maintain DNA integrity; polymorphisms in genes coding for these proteins can increase susceptibility to colorectal cancer (CRC) development. We analyzed a possible association of MLH1 -93G>A and 655A>G and XRCC1 Arg194Trp and Arg399Gln polymorphisms with CRC in Mexican patients. Genomic DNA samples were obtained from peripheral blood of 108 individuals with CRC (study group) at diagnosis and 120 blood donors (control group) from Western Mexico; both groups were mestizos. The polymorphisms were detected by PCR-RFLP. Association was estimated by calculating the odds ratio (OR). We found that the MLH1 and XRCC1 polymorphisms were in Hardy- Weinberg equilibrium. The MLH1 655A>G polymorphism in the 655G allele was associated with a 2-fold increase risk for CRC (OR = 2.04 and 95% confidence interval (95%CI) = 1.12-3.69; P A polymorphism allele was associated with a protective effect (OR = 0.60, 95%CI = 0.40-0.89; P = 0.01 in the -93A allele and OR = 0.32, 95%CI = 0.13-0.79; P = 0.01 in the AA genotype). The XRCC1 Arg194Trp and Arg399Gln polymorphisms did not show any significant associations. In conclusion, we found that MLH1 -93G>A and 655A>G polymorphisms are associated with CRC in Mexican patients
MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer.
DNA repair proteins maintain DNA integrity; polymorphisms in genes coding for these proteins can increase susceptibility to colorectal cancer (CRC) development. We analyzed a possible association of MLH1 -93G>A and 655A>G and XRCC1 Arg194Trp and Arg399Gln polymorphisms with CRC in Mexican patients. Genomic DNA samples were obtained from peripheral blood of 108 individuals with CRC (study group) at diagnosis and 120 blood donors (control group) from Western Mexico; both groups were mestizos. The polymorphisms were detected by PCR-RFLP. Association was estimated by calculating the odds ratio (OR). We found that the MLH1 and XRCC1 polymorphisms were in Hardy- Weinberg equilibrium. The MLH1 655A>G polymorphism in the 655G allele was associated with a 2-fold increase risk for CRC (OR = 2.04 and 95% confidence interval (95%CI) = 1.12-3.69; P A polymorphism allele was associated with a protective effect (OR = 0.60, 95%CI = 0.40-0.89; P = 0.01 in the -93A allele and OR = 0.32, 95%CI = 0.13-0.79; P = 0.01 in the AA genotype). The XRCC1 Arg194Trp and Arg399Gln polymorphisms did not show any significant associations. In conclusion, we found that MLH1 -93G>A and 655A>G polymorphisms are associated with CRC in Mexican patients