88 research outputs found
A Case of Liposarcoma With Peritonitis Due to Jejunal Perforation
A 21-year-old man, who had been treated for congenital dilatation of the bile duct 13 years previously, presented with an
acute abdomen. The physical examination suggested peritonitis, and an emergent laparotomy was performed. A perforation
was foundin the jejunum approximately 100 cm distal to the ligament of Treitz, followed by resection of a 60-cm jejunal
segment. No tumorous lesions were found during the operation, and the resected jejunal segment showed only focal
myxomatous thickening of the serosa. Despite intensive therapy, he died of uncontrollable septic shock 2 days after the
operation. Unexpectedly, however, histological examination revealed a liposarcoma, showing an unclassifiable histology.
From the distribution of the lesion and the histological findings, it is thought that a primary lesion was somewhere else,
covered by severe adhesions due to the previous operation, and that the tumor cells spreading from it could have caused the
jejunal perforation through vascular involvement. Although extremely rare, liposarcomas in the abdomen can cause intestinal
perforation. It is important for both clinicians andpathologists to carefully investigate the cause of an unusual clinical
presentation such as intestinal perforation
Polyoxyethylene hydrogenated castor oil modulates benzalkonium chloride toxicity: comparison of acute corneal barrier dysfunction induced by travoprost Z and travoprost.
To determine the element that modulates benzalkonium chloride (BAC) toxicity by using a new electrophysiological method to evaluate acute corneal barrier dysfunction induced by travoprost Z with sofZia (Travatan Z(®)), travoprost with 0.015% BAC (Travatan(®)), and its additives
Identification of 45 New Neutron-Rich Isotopes Produced by In-Flight Fission of a 238U Beam at 345 MeV/nucleon
A search for new isotopes using in-flight fission of a 345 MeV/nucleon 238U
beam has been carried out at the RI Beam Factory at the RIKEN Nishina Center.
Fission fragments were analyzed and identified by using the superconducting
in-flight separator BigRIPS. We observed 45 new neutron-rich isotopes: 71Mn,
73,74Fe, 76Co, 79Ni, 81,82Cu, 84,85Zn, 87Ga, 90Ge, 95Se, 98Br, 101Kr, 103Rb,
106,107Sr, 108,109Y, 111,112Zr, 114,115Nb, 115,116,117Mo, 119,120Tc,
121,122,123,124Ru, 123,124,125,126Rh, 127,128Pd, 133Cd, 138Sn, 140Sb, 143Te,
145I, 148Xe, and 152Ba
Comparison of Corneal Safety and Intraocular Pressure?Lowering Effect of Tafluprost Ophthalmic Solution with Other Prostaglandin Ophthalmic Solutions
Purpose: The benzalkonium chloride (BAK) content of tafluprost ophthalmic solution (TaprosR: tafluprost) has been reduced to balance corneal safety and preservative effectiveness (old formulation: 0.01%; new formulation: 0.001%). However, no reports have been published on its clinical effect. Therefore, we conducted a clinical research study to compare the safety of BAK-reduced tafluprost on the ocular surface with other prostaglandin ophthalmic solutions. Methods: This clinical study included 28 glaucoma patients (28 eyes) with a treatment history of latanoprost ophthalmic solution (XalatanR) or travoprost ophthalmic solution (Travatan Z R), who presented with corneal epithelial disorders. The subjects were switched to BAK-reduced tafluprost, and its effect on the ocular surface was examined after 1 and 2 months of treatment [using fluorescein staining score, hyperemia, tear film breakup time, and intraocular pressure (IOP) lowering]. Results: In all analyzed subjects (N=27), the fluorescein staining score was significantly improved after switching to BAK-reduced tafluprost (P<0.0001). Conversely, the IOP-lowering effect was not notably changed. The subjects switched from latanoprost (n=10) showed significant improvement in fluorescein staining score (P<0.05) as well as in IOP lowering (P<0.01). The subjects switched from travoprost (n=17) also showed significant improvement in fluorescein staining score (P<0.001), but without a significant change in IOP lowering. Conclusions: Tafluprost with reduced BAK has potential as a superior antiglaucoma drug, not only for its IOP-lowering effect, but also for its good corneal safety profile
Serum selenium and liposoluble vitamins in Japanese Black cows that had stillborn calves
Effect of Interlayer Thickness on Fatigue Behavior in A5052 Aluminum Alloy with Diamond-Like Carbon/Anodic-Oxide Hybrid Coating
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