Letter from T. Fisher Unwin to John Muir, 1913 Nov 10.

T. Fisher Unwin,l, Adelphi Terrace,London, W.C. November 10. 1913As perhaps you are aware, from time to time I have published, or rather sold in England, small editions of your books which have been issued by the Century Co. and other forms; for instance the volume entitled The Mountains of California . My object in writing now is that in looking back though some old correspondence with a Mr. J. B. Miller of Dunbar, I notice a remark that you came from Scotland and as. I understand it are a native of Dunbar, I notice if this is correct? The old gentleman died some dozen or more years ago and I am merely relying on my memory of that letter. My object also arises from the fact that I have in preparation for publication a volume on the Miller family, who were printers, publishers, authors and booksellers at the beginning of the last Century, indeed there are two or three generations of them and it occurred to me that if you knew Dunbar, you might perhaps be able to give me some information in regard to this family. I need hardly say it would05604 be a pleasure to hear from you in any case as in past years I have been your publisher.[illegible]0560

Optical fibre digital pulse-position-modulation assuming a Gaussian received pulse shape

The abundance in bandwidth available in the best monomode fibres may be exchanged for improved receiver sensitivity by employing digital PPM. The paper presents a performance and optimisation analysis for a digital PPM coding scheme operating over a fibre channel employing a PIN-BJT receiver and assuming a Gaussian received pulse shape. The authors present original results for a 50 Mbit/s, 1.3 μm wavelength digital PPM system and conclude that, provided the fibre bandwidth is several times that of the data rate, digital PPM can outperform commercially available PIN-BJT binary PCM system

Radio Pulse Properties of the Millisecond Pulsar PSR J0437-4715. I. Observations at 20cm

We present a total of 48 minutes of observations of the nearby, bright millisecond pulsar PSR J0437-4715 taken at the Parkes radio observatory in Australia. The data were obtained at a central radio frequency of 1380 MHz using a high-speed tape recorder that permitted coherent Nyquist sampling of 50 MHz of bandwidth in each of two polarizations. Using the high time resolution available from this voltage recording technique, we have studied a variety of single-pulse properties, most for the first time in a millisecond pulsar. We find no evidence for "diffractive" quantization effects in the individual pulse arrival times or amplitudes as have been reported for this pulsar at lower radio frequency using coarser time resolution (Ables et al. 1997). Overall, we find that the single pulse properties of PSR J0437-4715 are similar to those of the common slow-rotating pulsars, even though this pulsar's magnetosphere and surface magnetic field are several orders of magnitude smaller than those of the general population. The pulsar radio emission mechanism must therefore be insensitive to these fundamental neutron star properties.Comment: 24 Postscript pages, 11 eps figures. Accepted for publication in the Astrophysical Journal. Abbreviated abstract follow

Causes of and alternatives to medication for behaviours that challenge in people with intellectual disabilities: direct care providers' perspectives

Behaviours that challenge (BtC), such as aggression and self-injury, are manifested by many people with intellectual disabilities (ID). National and international guidelines recommend non-pharmacological psychosocial intervention before considering medication to address BtC. Support staff play a pivotal role in the prescription process. Using coproduction, we developed a training programme for support staff, called SPECTROM, to give them knowledge and empower them to question inappropriate prescriptions and ask for the discontinuation of medication if appropriate and instead look for ways to help people with ID when they are distressed without relying on medication. We have presented data from two focus groups that we conducted during the development of SPECTROM: one that included support staff, and another that had service managers and trainers. In these focus groups, we explored participants’ views on the use of medication to address BtC with a particular emphasis on the causes of and alternatives to medication for BtC. Along with the participants’ views, we have also presented how we have addressed these issues in the SPECTROM resources

Does lighting affect pedestrian flows? A pilot study in Lund, Market Harborough and Dublin

A study records pedestrian footfalls in Lund, Dublin and Market Harborough during the day and after dark, either side of the Autumn 2016 clock change, using the change of end of civil twilight time to measure the effect of different lighting levels at the same clock time on footfall rates. Examination of total footfalls on weekdays and at weekends found significant decreases in counts after the clock change, on 5/6 sites on weekdays and half the sites at weekends. Further analysis found that the percentage decrease in the counts in the test period (same time/day of the week, light one week, dark the next) was more than in the control period (same time/day of the week, light both weeks), in 79% of counting sessions. The findings demonstrate higher reduction in footfalls on weekdays in mixed use areas, such as the sites selected in Dublin, and on Sundays in non-central locations

Quantifying the direct and indirect protection provided by insecticide treated bed nets against malaria

Long lasting insecticidal nets (LLINs) provide both direct and indirect protection against malaria. As pyrethroid resistance evolves in mosquito vectors, it will be useful to understand how the specific benefits LLINs afford individuals and communities may be affected. Here we use modelling to show that there is no minimum LLIN usage needed for users and non-users to benefit from community protection. Modelling results also indicate that pyrethroid resistance in local mosquitoes will likely diminish the direct and indirect benefits from insecticides, leaving the barrier effects intact, but LLINs are still expected to provide enhanced benefit over untreated nets even at high levels of pyrethroid resistance

Landing and catalytic characterization of individual nanoparticles on electrode surfaces

We demonstrate a novel and versatile pipet-based approach to study the landing of individual nanoparticles (NPs) on various electrode materials without any need for encapsulation or fabrication of complex substrate electrode structures, providing great flexibility with respect to electrode materials. Because of the small electrode area defined by the pipet dimensions, the background current is low, allowing for the detection of minute current signals with good time resolution. This approach was used to characterize the potential-dependent activity of Au NPs and to measure the catalytic activity of a single NP on a TEM grid, combining electrochemical and physical characterization at the single NP level for the first time. Such measurements open up the possibility of studying the relation between the size, structure and activity of catalyst particles unambiguously

Multi-Epoch Observations of Survey Sources

Five objects mapped as part of a VLBI survey have been re-observed at 5 GHz, and four of them have also been observed at 10 GHz. Three of the objects show no substantial structural variations: an upper limit of 2c can be placed on the apparent relative velocities of the components. One object (0711+356) shows structural variations which are mostly simply described in terms of a superluminal contraction. The remaining object (3C371, 1807+698) shows substantial structural variations which suggest that it probably is a superluminal source. The source 0710+439 is especially interesting as it consists of a central flat-spectrum core component straddled by two compact steep-spectrum components

Dietary strategies for remission of type 2 diabetes: A narrative review

Type 2 diabetes (T2DM) is a growing health issue globally, which, until recently, was considered to be both chronic and progressive. Although having lifestyle and dietary changes as core components, treatments have focused on optimising glycaemic control using pharmaceutical agents. With data from bariatric surgery and, more recently, total diet replacement (TDR) studies that have set out to achieve remission, remission of T2DM has emerged as a treatment goal. A group of specialist dietitians and medical practitioners was convened, supported by the British Dietetic Association and Diabetes UK, to discuss dietary approaches to T2DM and consequently undertook a review of the available clinical trial and practice audit data regarding dietary approaches to remission of T2DM. Current available evidence suggests that a range of dietary approaches, including low energy diets (mostly using TDR) and low carbohydrate diets, can be used to support the achievement of euglycaemia and potentially remission. The most significant predictor of remission is weight loss and, although euglycaemia may occur on a low carbohydrate diet without weight loss, which does not meet some definitions of remission, it may rather constitute a ‘state of mitigation’ of T2DM. This technical point may not be considered as important for people living with T2DM, aside from that it may only last as long as the carbohydrate restriction is maintained. The possibility of actively treating T2DM along with the possibility of achieving remission should be discussed by healthcare professionals with people living with T2DM, along with a range of different dietary approaches that can help to achieve this