Global deceleration and inward movements of X-ray knots and rims of RCW 103

Kinematics of shocks, ejecta knots, and the compact remnant of a supernova remnant gives an insight into the nature of the progenitor and surrounding environment. We report on a proper motion measurement of X-ray knots and rims of the magnetar-hosting supernova remnant RCW 103. Chandra data obtained in three epochs, 1999, 2010, and 2016 are used. We find a global deceleration of 12 knots and rims both in northern and southern regions within the last $\sim 24$ yrs, even though its age is thought to be larger than 2 kyr. Some of them even changed their moving directions from outward ($\sim 1,000$ km s$^{-1}$) to inward ($\sim -2,000$ km s$^{-1}$). Our findings can be explained with a collision with a high-density medium both in the northern and southern edges of the remnant, although the remnant may still be expanding in the wind-blown cavity. The proper motion of the associated magnetar 1E161348$-$5055 is possibly detected with a velocity of $\approx 500$ km s$^{-1}$.Comment: 8 pages, 4 figures, accepted for publication in Ap

国語科における「話し合い」学習の理論と実践

早大学位記番号:新7390早稲田大

Lateral Growth of Uniformly Thin Gold Nanosheets Facilitated by Two-Dimensional Precursor Supply

The nanosheets of highly symmetric materials with a face-centered cubic lattice such as gold have been synthesized by adsorbing the precursors on a flat surface, whose chemical specificity induces the anisotropy of growth rates. We have succeeded in the fabrication of gold nanosheets in a hydrophilic space inside highly separated bilayers, which work as two-dimensional hydrophilic reactors, in a hyperswollen lamellar liquid crystalline phase of an amphiphile solution. One of the physical properties, amphiphilicity, confines the ingredients therein. The nanosheets can only grow in the in-plane direction due to the inhibition of the out-of-plane growth rather than the anisotropy of growth rates probably. Thus, the synthesis can be accelerated; the particles can be completed within 15 min. As not relying on chemical specificity, silver nanosheets could also be synthesized in the same way. The suspension of gold and silver nanosheets without any amphiphiles could be obtained, and the solvent is replaceable. We found that the width of the obtained gold nanosheets is proportional to the Reynolds number of the solution because the area of the bilayer in the hyperswollen lamellar phase depends on shear stress. This implies that the areas of gold nanosheets depend on the areas of the bilayers, and it can be controlled by changing the Reynolds number. This method could be widely used to continuously obtain large-area nanosheets of various materials in a roll-to-roll manufacturing process.Koki Sasaki, suyoshi Okue, Takuto Nakai et al. Lateral Growth of Uniformly Thin Gold Nanosheets Facilitated by Two-Dimensional Precursor Supply. Langmuir, 37 (19), 5872-5877, May 18, © 2021 American Chemical Society. https://doi.org/10.1021/acs.langmuir.1c0034

Thin ZIF-8 nanosheets synthesized in hydrophilic TRAPs

The preparation method of nanosheets using hyperswollen lyotropic lamellar phases, the ‘two-dimensional reactor in amphiphilic phases (TRAP) method’, has successfully provided nanosheets of various non-layered materials. Previously reported examples started from a single hydrophobic or hydrophilic precursor and multiple hydrophobic precursors. Here, we propose a synthesis method of nanosheets of ZIF-8, zinc 2-methylimidazolate, with a sodalite-like framework. They grow up to a few nanometers of thickness and several hundred nanometers of width with neither aggregation nor impurities from multiple hydrophilic precursors in the stoichiometric ratio inside the hydrophilic TRAPs consisting of the amphiphile Brij L4. The thin nanosheets of ZIF-8 doped with Co2+(Co-ZIF-8) synthesized by the same method maintained a high specific surface area after calcination. Therefore, the oxygen reduction reaction (ORR) activity of the calcined Co-ZIF-8 NSs for fuel cells becomes higher than that of the calcined conventional Co-ZIF-8 crystals.Sasaki K., Okue T., Shu Y., et al. Thin ZIF-8 nanosheets synthesized in hydrophilic TRAPs. Dalton Transactions 50, 10394 (2021); https://doi.org/10.1039/d1dt01507a

Aerobic and Anaerobic Biotransformation of Bile Acids by Escherichia coli (III)

The oxidation/reduction reactions of bile acids by Escherichia coli (E. coli) K-12 were examined in both Davis and brain-heart infusion (BHI) media under aerobic and anaerobic conditions. The pH in the Davis medium changed by almost the same amount, around pH 6.5?7.0 in both aerobic and anaerobic cultures, but the pH in the BHI medium was different in both cultures, that is, about pH 9.0 in the aerobic culture but only about 6.5 in the anaerobic culture. The growth curve of E. coli in the Davis medium showed a similar pattern in both conditions. Cholic acid (CA) was oxidized to 3α12α-dihydroxy-7-oxo-5β-cholanoic acid (3α12α7=O) in both cultures, but the reaction in the anaerobic culture was somewhat slower than that in the aerobic culture. On the other hand, reduction of 3α12α7=O to CA did not occur in the aerobic culture, but about 10% reduction was observed in the anaerobic culture after 4 days. These data suggest that the oxidation/reduction reaction of E. coli was oxidative in aerobic culture but reductive in anaerobic culture and these characteristics were not due to the changes in the pH of the medium. The reactions of CA and glycocholic acid to crude 7α-HSDH prepared from E. coli were examined and it was found that both free and conjugated CA as a substrate for the 7α-HSDH showed similar Km values

Amorphous Aluminosilicate Nanosheets as Universal Precursors for the Synthesis of Diverse Zeolite Nanosheets for Polymer‐Cracking Reactions

Zeolites catalyze some reactions in their molecular-sized pores, but large molecules can react only on their external surface. Zeolite-nanosheets (NSs) have been developed as catalysts for large molecules. The previously reported methods to synthesize zeolite-NSs are specialized for each zeolite type. Here we propose a new method to synthesize various zeolite-NSs from the same amorphous aluminosilicate NSs (AAS-NSs) as a universal precursor. We successfully synthesized the unprecedented AAS-NSs in the hydrophilic space of the stable hyperswollen lyotropic lamellar (HL) phase. The four zeolite types could be obtained from the single-species AAS-NSs. These results imply that this method enables us to synthesize almost all types of zeolite-NSs. Moreover, the synthesized CHA-NSs have great potential for various applications because of their thickness and large external surface area.Sasaki Koki, Gaitan Jose A. Hernandez, Okue Tsuyoshi, et al. Amorphous Aluminosilicate Nanosheets as Universal Precursors for the Synthesis of Diverse Zeolite Nanosheets for Polymer‐Cracking Reactions. Angewandte Chemie 134, (2022); https://doi.org/10.1002/ange.202213773

Superficial Carcinoma of the Esophagus

Four cases of esophageal carcinoma in which the invasion is limited to the mucosal layer (m-carcinoma) and 7 cases of it in which the invasion invades the submucosal layer (sm-carcinoma) are studied. In the cases of m-carcinoma, both lymphatic invasion and blood vessel invasion were not found. On the other hand, lymphatic invasion was noted in 4 cases among 7 cases of sm-carcinoma, and in these 4 oases, lymphatic invasion or blood vessel invasion was demonstrated in the primary sites. Among 4 patients who had lymph node metastasis, 2 died of the recurrence of carcinoma, and the other 2 died of other diseases. The prognosis of patients without lymph node metastasis was satisfactory. The best way to elevate the prognosis of esophageal carcinoma is to discover it at the stage of m-carcinoma, and in order to achieve it, endoscopic observation combined withh the Lugol-staining method is most influential. It is also recommended to perform the esophageal endoscopic examination with patients visiting us with other diseases

Host Cytokine Responses of Pigeons Infected with Highly Pathogenic Thai Avian Influenza Viruses of Subtype H5N1 Isolated from Wild Birds

Highly pathogenic avian influenza virus (HPAIV) of the H5N1 subtype has been reported to infect pigeons asymptomatically or induce mild symptoms. However, host immune responses of pigeons inoculated with HPAIVs have not been well documented. To assess host responses of pigeons against HPAIV infection, we compared lethality, viral distribution and mRNA expression of immune related genes of pigeons infected with two HPAIVs (A/Pigeon/Thailand/VSMU-7-NPT/2004; Pigeon04 and A/Tree sparrow/Ratchaburi/VSMU-16-RBR/2005; T.sparrow05) isolated from wild birds in Thailand. The survival experiment showed that 25% of pigeons died within 2 weeks after the inoculation of two HPAIVs or medium only, suggesting that these viruses did not cause lethal infection in pigeons. Pigeon04 replicated in the lungs more efficiently than T.sparrow05 and spread to multiple extrapulmonary organs such as the brain, spleen, liver, kidney and rectum on days 2, 5 and 9 post infection. No severe lesion was observed in the lungs infected with Pigeon04 as well as T.sparrow05 throughout the collection periods. Encephalitis was occasionally observed in Pigeon04- or T.sparrow05-infected brain, the severity, however was mostly mild. To analyze the expression of immune-related genes in the infected pigeons, we established a quantitative real-time PCR analysis for 14 genes of pigeons. On day 2 post infection, Pigeon04 induced mRNA expression of Mx1, PKR and OAS to a greater extent than T.sparrow05 in the lungs, however their expressions were not up-regulated concomitantly on day 5 post infection when the peak viral replication was observed. Expressions of TLR3, IFNα, IL6, IL8 and CCL5 in the lungs following infection with the two HPAIVs were low. In sum, Pigeon04 exhibited efficient replication in the lungs compared to T.sparrow05, but did not induce excessive host cytokine expressions. Our study has provided the first insight into host immune responses of pigeons against HPAIV infection