Identification of Criteria for Successfully Establishing Computer-based Training Projects in Business and Industry

Human Resources Development with Computer-Based Trainin

Social Sustainability and Ulaanbaatar’s ‘Ger Districts’: Access and Mobility Issues and Opportunities

This paper explores the concept of social sustainability in Ulaanbaatar’s ger districts in relation to access and mobility. Although ger districts are well-established in Mongolian culture as ephemeral encampments with transient residents, contemporary ger districts have become large and permanent residential districts that are now home to an estimated one-third of the country’s population. The more recent growth of the ger districts has taken place in three decades since Mongolia embraced market-based liberal economics, coinciding with waves of socially and economically-motivated urbanisation. More recently, difficult environmental conditions in rural Mongolia have created new waves of migration. The unfolding situation means that the ger districts have grown with little of the forward planning present in other built areas of the city. In turn, this has led to significant imbalances in the provision of transport services into the ger districts and the problems of access and mobility that this paper has highlighted. This paper has identified community-based local transport and delivery services as one potential means for addressing existing access and mobility shortcomings. Such approaches could provide temporary or complementary services alongside other public policy approaches

Soft-Wall Stabilization

We propose a general class of five-dimensional soft-wall models with AdS metric near the ultraviolet brane and four-dimensional Poincar\'e invariance, where the infrared scale is determined dynamically. A large UV/IR hierarchy can be generated without any fine-tuning, thus solving the electroweak/Planck scale hierarchy problem. Generically, the spectrum of fluctuations is discrete with a level spacing (mass gap) provided by the inverse length of the wall, similar to RS1 models with Standard Model fields propagating in the bulk. Moreover two particularly interesting cases arise. They can describe: (a) a theory with a continuous spectrum above the mass gap which can model unparticles corresponding to operators of a CFT where the conformal symmetry is broken by a mass gap, and; (b) a theory with a discrete spectrum provided by linear Regge trajectories as in AdS/QCD models.Comment: 27 pages, 6 figures, 1 table. v2: references added, version to appear in NJP Focus Issue on Extra Dimension

Residual Stresses in Alloy IN718 Produced Through Modulated Laser Powder Bed Fusion

Background: Laser powder bed fusion (L-PBF) additive manufacturing (AM) is used for building metallic parts layer-by-layer and often generates non-uniform thermal gradients between layers during fabrication, resulting in the development of residual stresses when parts are cooled down. Objective: The impact of modulated laser used during the L-PBF process on residual stresses in Inconel 718 (IN718) material was investigated. The impact of build directions on residual stress is also determined. Methods: The contour method is employed to measure the full-field residual stress component on the cross-section of samples. A complementary residual stress measurement method, incremental hole drilling, was employed for obtaining in-plane residual stress components. Results: The results show that the residual stress distribution is sensitive to the build direction, with a higher magnitude of residual stress in the direction of build than that in the transverse direction. Multiple measurements with the same manufacturing parameters show good repeatability. Conclusion: Residual stresses in the as-built parts are significant and hence a further consideration regarding relieving residual stresses is required when post-thermal treatments are developed

Covariant Approaches to Superconformal Blocks

We develop techniques for computing superconformal blocks in 4d superconformal field theories. First we study the super-Casimir differential equation, deriving simple new expressions for superconformal blocks for 4-point functions containing chiral operators in theories with N-extended supersymmetry. We also reproduce these results by extending the "shadow formalism" of Ferrara, Gatto, Grillo, and Parisi to supersymmetric theories, where superconformal blocks can be represented as superspace integrals of three-point functions multiplied by shadow three-point functions.Comment: 32 page

A single transcription factor is sufficient to induce and maintain secretory cell architecture

We hypothesized that basic helix–loop–helix (bHLH) MIST1 (BHLHA15) is a “scaling factor” that universally establishes secretory morphology in cells that perform regulated secretion. Here, we show that targeted deletion of MIST1 caused dismantling of the secretory apparatus of diverse exocrine cells. Parietal cells (PCs), whose function is to pump acid into the stomach, normally lack MIST1 and do not perform regulated secretion. Forced expression of MIST1 in PCs caused them to expand their apical cytoplasm, rearrange mitochondrial/lysosome trafficking, and generate large secretory granules. Mist1 induced a cohort of genes regulated by MIST1 in multiple organs but did not affect PC function. MIST1 bound CATATG/CAGCTG E boxes in the first intron of genes that regulate autophagosome/lysosomal degradation, mitochondrial trafficking, and amino acid metabolism. Similar alterations in cell architecture and gene expression were also caused by ectopically inducing MIST1 in vivo in hepatocytes. Thus, MIST1 is a scaling factor necessary and sufficient by itself to induce and maintain secretory cell architecture. Our results indicate that, whereas mature cell types in each organ may have unique developmental origins, cells performing similar physiological functions throughout the body share similar transcription factor-mediated architectural “blueprints.

Problems persist in reporting of methods and results for the WOMAC measure in hip and knee osteoarthritis trials

Purpose The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is a commonly used outcome measure for osteoarthritis. There are different versions of the WOMAC (Likert, visual analogue or numeric scales). A previous review of trials published before 2010 found poor reporting and inconsistency in how the WOMAC was used. This review explores whether these problems persist. Methods This systematic review included randomised trials of hip and/or knee osteoarthritis published in 2016 that used the WOMAC. Data were extracted on the version used, score range, analysis and results of the WOMAC, and whether these details were clearly reported. Results This review included 62 trials and 41 reported the WOMAC total score. The version used and item range for the WOMAC total score were unclear in 44% (n = 18/41) and 24% (n = 10/41) of trials, respectively. The smallest total score range was 0–10 (calculated by averaging 24 items scored 0–10); the largest was 0–2400 (calculated by summing 24 items scored 0–100). All trials reported the statistical analysis methods but only 29% reported the between-group mean difference and 95% confidence interval. Conclusion Details on the use and scoring of the WOMAC were often not reported. We recommend that trials report the version of the WOMAC and the score range used. The between-group treatment effect and corresponding confidence interval should be reported. If all the items of the WOMAC are collected, the total score and individual subscale scores should be presented. Better reporting would facilitate the interpretation, comparison and synthesis of the WOMAC score in trials

Measuring the Polarization of Boosted Hadronic Tops

We propose a new technique for measuring the polarization of hadronically decaying boosted top quarks. In particular, we apply a subjet-based technique to events where the decay products of the top are clustered within a single jet. The technique requires neither b-tagging nor W-reconstruction, and does not rely on assumptions about either the top production mechanism or the sources of missing energy in the event. We include results for various new physics scenarios made with different Monte Carlo generators to demonstrate the robustness of the technique.Comment: v2: version accepted for publication in JHE