46 research outputs found
Puente sobre el valle del Elz - Alemania Occidental
This bridge is some 30 km from Koblenz, and runs over a deep gulley. It is 380 m long, 30 m wide, and rests on a single row of octagonal pylons, some of which are 100 m high. It has been constructed by successive overhangs. The article describes the project in detail, both constructively and aesthetically.<br><br>Está situado a unos 30 km al oeste de Coblenza y cruza un profundo valle. La obra tiene 380 m de longitud, 30 m de anchura y una sola fila de pilas octogonales, alguna de las cuales alcanza los 100 m de altura. Se ha construido por el sistema de avance en voladizo, explicándose en el artículo las características de proyecto, constructivas y estáticas
Der gerade Stab mit geschlossenem d�nnwandigen Profil unter n�herungsweiser Ber�cksichtigung der Schub- und Querschnittsdeformationen
Deletions in 16p13 including GRIN2A in patients with intellectual disability, various dysmorphic features, and seizure disorders of the rolandic region.
Contains fulltext :
88225.pdf (publisher's version ) (Closed access)Seizure disorders of the rolandic region comprise a spectrum of different epilepsy syndromes ranging from benign rolandic epilepsy to more severe seizure disorders including atypical benign partial epilepsy/pseudo-Lennox syndrome,electrical status epilepticus during sleep, and Landau-Kleffner syndrome. Centrotemporal spikes are the unifying electroencephalographic hallmark of these benign focal epilepsies, indicating a pathophysiologic relationship between the various epilepsies arising from the rolandic region. The etiology of these epilepsies is elusive, but a genetic component is assumed given the heritability of the characteristic electrographic trait. Herein we report on three patients with intellectual disability, various dysmorphic features, and epilepsies involving the rolandic region, carrying previously undescribed deletions in 16p13. The only gene located in the critical region shared by all three patients is GRIN2A coding for the alpha-2 subunit of the neuronal N-methyl-D-aspartate(NMDA) receptor.1 september 201
Akustische Stimulation der Cochlea über CI Elektroden
Background Myelin oligodendrocyte glycoprotein (MOG) antibodies have been recently described in children with acute disseminating encephalomyelitis (ADEM), but the clinical and neuroradiological characterisation of this subgroup is lacking. Objective To compare the clinical and neuroradiological features of paediatric ADEM with and without MOG antibodies. Methods Clinical course, cerebrospinal fluid (CSF)-, MRI studies, outcome and MOG status of 33 paediatric ADEM prospectively studied were reviewed. Results MOG antibodies (median 1: 2560; range 1: 160-1: 20 480) were detected in 19 children with ADEM. The majority of children showed a decline of serum MOG-IgG titres over time. Children with MOG antibodies did not differ in their age at presentation, sex ratio, the presence of oligoclonal bands, clinical symptoms or initial severity, apart from