Report on Owned Dog Population Survey In Lingayen, Philippines

The Philippines is among the Southeast Asian countries that has a long-standing problem with rabies. About 200 people die of rabies each year in the Philippines, and most are attributed to dog bite cases (Deray, 2015). The sources of infection of more than 95% of human rabies cases worldwide have been reported to be domestic dogs (Cleaveland, et al., 2006). Focusing on the main source rather than the human population, is therefore, the best strategy to eliminate rabies. The World Health Organization (WHO) recommends covering at least 70% of the existing domestic dog population with rabies vaccination in the shortest time possible (WHO, 2015). Experts and epidemiologists also recommend maintaining the population immunity above this critical level for at least twelve months, which also interrupts the transmission of rabies among the target population (Coleman & Dye, 1996; Cleaveland, et al., 2003; Hampson, et al., 2009; Morters, et al., 2013)

Report on Owned Dog Population Survey In Zamboanga, Philippines

The Philippines is among the Southeast Asian countries that has a long-standing problem with rabies. About 200 people die of rabies each year in the Philippines, and most are attributed to dog bite cases (Deray, 2015). The sources of infection of more than 95% of human rabies cases worldwide have been reported to be domestic dogs (Cleaveland, et al., 2006). Focusing on the main source rather than the human population, is therefore, the best strategy to eliminate rabies. The World Health Organization (WHO) recommends covering at least 70% of the existing domestic dog population with rabies vaccination in the shortest time possible (WHO, 2015). Experts and epidemiologists also recommend maintaining the population immunity above this critical level for at least twelve months, which also interrupts the transmission of rabies among the target population (Coleman & Dye, 1996; Cleaveland, et al., 2003; Hampson, et al., 2009; Morters, et al., 2013)

HAEMOGRAM OF NIGERIAN MONGREL BITCH AT DIFFERENT STAGES OF THE REPRODUCTIVE CYCLE

The haematologic parameters of the Nigerian Mongrel bitch were investigated at different stages of the reproductive cycle to determine their clinical values. Results showed that red blood cell (RBC) counts were highest during anoestrus, with a mean of 5.09  0.62 x 106/µL, while lowest values were recorded during pregnancy, the difference was significant (P<0.05). White blood cell (WBC) counts, packed cell volume (PCV) and haemoglobin concentration (Hb) showed an increasing pattern from anoestrus to proestrus and then decreased with transition from proestrus to oestrus. Total WBC counts were highest during dioestrus and almost twice the value recorded in pregnancy. It appears that WBC count may be used for pregnancy diagnosis in the Nigerian Mongrel bitch

A REVIEW ON A FLASH CHROMATOGRAPHY

ABSTRACT Flash chromatography is rapid form of preparative column chromatography-preparative liquid chromatography based upon an air pressure driven hybrid of medium and short column chromatography optimized for rapid separation of organic compounds. As technology has evolved available guidelines for normal-phase flash chromatography have become less relevant. Years of experience performing chromatography with disposable columns have been condensed into simple guidelines useful for translating TLC results into either isocratic-or gradient-flash chromatography. The described studies should provide researchers with a means of selecting adequate columns and guidelines to reduce the waste of solvents, silica, time, and money. Modern flash chromatography systems are sold as pre-packed plastic cartridges and the solvent is pumped through the cartridge. These systems may also be linked with detectors and fraction collectors providing automation. The introduction of gradient pumps has resulted in quicker separations and less solvent usage

Sperm Reserves and its Relationship to Parameters of the Testis, Epididymis and Vas Deferens of Local Cocks in the Sahel Region of Nigeria

ABSTRACT The morphometry and sperm reserves of the testis, epididymis and vas deferens of 19 sexually active adult local cocks were studied. The average live weight of the cocks was 1.879±0.316 kg and that of the paired testis, epididymis, vas deferens were 12.17±4.75 g, 0.52±0.19 g and 1.36±0.56 g, respectively. The length of the testis, epididymis and vas deferens were 3.42±0.50 cm, 1.91±0.38 cm and 11.5±1.34 cm, respectively. In majority of cases, the parameters of the left organs were insignificantly greater than those of the right. The width, thickness, circumference and volume of the testis as well as the diameter and volume of the epididymis and vas deferens were recorded. There were strong positive correlation between the weight of the testis and epididymis (r=±0.82) or vas deferens (r=±0.66). The gonadal sperm reserve was 2.11±1.11 x 10 9 sperm (173.7±71.5 x 10 6 sperm g -1 ) and the extrangonadal sperm, 1.77x 10 9 sperm. The vas deferens with 89.8% of the extragonadal sperm reserved as the main storage organ of sperm for use during threading. Sperm reserve was positively correlated to body weight (r=±0.77, P = 0.000) and to the length of the testis (r=±0.55, P = 0.015). This may suggest that body weight and testicular length are indicators of fertility. The high gonadal sperm and hence reproductive potential may reflect an adaptive change in the local cocks, which have a very high mating frequency per day

Suppression of Superconductivity in YBCO/LCMO Superlattices

The competition of superconductivity and magnetism in superlattices composed of alternating YBa$_2$Cu$_3$O$_{7-d}$ and La$_{0.67}$Ca$_{0.33}$MnO$_{3}$ thin films is investigated using low-energy optical spectroscopy. The thickness of the superconducting YBCO layers is varied from 30 nm to 20 nm while the thickness of the magnetic LCMO layers is kept constant at 20 nm. We clearly observe that the superconducting condensate density in the superconducting state of superlattice is drastically reduced by the magnetic subsystem which may be connected with proximity effects that distort the gap symmetry and thus suppress superconductivity.Comment: 4 pages, 4 figure

A Novel Approach for Shadow Detection and Removal from Image

Image processing has been one region of studies that draws the interest of extensive form of researchers. Surveillance structures are in big demand specially, for their packages in public areas, consisting of airports, stations, subways, front to buildings and mass events. Shadow occurs while objects consist of light from light source. Shadows offer wealthy information about the item shapes as well as light orientations. Shadow in picture reduces the reliability of many computer imaginative and prescient algorithms. Shadow regularly degrades the visual exceptional of an image. Shadow removal in an image is pre-processing step for computer imaginative and prescient algorithm and image enhancement. Shadow detection and removal in numerous actual lifestyles situations consisting of surveillance device and laptop vision machine remained a hard project. Shadow in visitors surveillance system might also misclassify the actual item, lowering the gadget overall performance

Yield Stability in Pigeon pea Hybrids [Cajanus cajan (L.) Millsp.] Under Varying Agro-Climatic Regions

Twelve pigeonpea genotypes comprising ten hybrids and two controls were evaluated at three environments during rainy season of 2012-13, to study genotype × environment interaction for yield and related traits. Analysis of variance in each environment and on a pooled basis expressed a significant difference among genotypes for yield and yield contributing characters except for 100 seed weight. Genotype × environment (linear) interactions were found significant for days to 50% flowering, plant height, primary and secondary branches per plant, pods per plant, seeds per pod, grain yield per plant and yield (kg/ha) except days to maturity and 100 seed weight. The regression and GGE biplot methods were used for analysis. Both methods identified ICPH 2671, ICPH 2740, ICPH 3933 and ICPH 3762 as stable hybrids. The GGE biplot explained higher proportion of the mean sum of squares of the G×E interaction and was more informative with regards to environments and their genotypic performance than the regression method. Hybrids ICPH 2671, ICPH 2740, ICPH 3762 and ICPH 3933 showed stability for the yield and yield components and could be recommended for cultivation

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment.

The currently available techniques for the safety evaluation of candidate drugs are usually cost-intensive and time-consuming and are often insufficient to predict human relevant cardiotoxicity. The purpose of this study was to develop an in vitro repeated exposure toxicity methodology allowing the identification of predictive genomics biomarkers of functional relevance for drug-induced cardiotoxicity in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The hiPSC-CMs were incubated with 156 nM doxorubicin, which is a well-characterized cardiotoxicant, for 2 or 6 days followed by washout of the test compound and further incubation in compound-free culture medium until day 14 after the onset of exposure. An xCELLigence Real-Time Cell Analyser was used to monitor doxorubicin-induced cytotoxicity while also monitoring functional alterations of cardiomyocytes by counting of the beating frequency of cardiomyocytes. Unlike single exposure, repeated doxorubicin exposure resulted in long-term arrhythmic beating in hiPSC-CMs accompanied by significant cytotoxicity. Global gene expression changes were studied using microarrays and bioinformatics tools. Analysis of the transcriptomic data revealed early expression signatures of genes involved in formation of sarcomeric structures, regulation of ion homeostasis and induction of apoptosis. Eighty-four significantly deregulated genes related to cardiac functions, stress and apoptosis were validated using real-time PCR. The expression of the 84 genes was further studied by real-time PCR in hiPSC-CMs incubated with daunorubicin and mitoxantrone, further anthracycline family members that are also known to induce cardiotoxicity. A panel of 35 genes was deregulated by all three anthracycline family members and can therefore be expected to predict the cardiotoxicity of compounds acting by similar mechanisms as doxorubicin, daunorubicin or mitoxantrone. The identified gene panel can be applied in the safety assessment of novel drug candidates as well as available therapeutics to identify compounds that may cause cardiotoxicity