121 research outputs found

    PHM12 COST-EFFECTIVENESS OF DASATINIBVS IMATINIB 800 MG/ DAY IN PATIENTS WITH IMATINIB-RESISTANT CHRONIC MYELOID LEUKEMIA IN SPAIN

    Get PDF

    Statistical analysis of coherent structures in transitional pipe flow

    Get PDF
    Numerical and experimental studies of transitional pipe flow have shown the prevalence of coherent flow structures that are dominated by downstream vortices. They attract special attention because they contribute predominantly to the increase of the Reynolds stresses in turbulent flow. In the present study we introduce a convenient detector for these coherent states, calculate the fraction of time the structures appear in the flow, and present a Markov model for the transition between the structures. The fraction of states that show vortical structures exceeds 24% for a Reynolds number of about Re=2200, and it decreases to about 20% for Re=2500. The Markov model for the transition between these states is in good agreement with the observed fraction of states, and in reasonable agreement with the prediction for their persistence. It provides insight into dominant qualitative changes of the flow when increasing the Reynolds number.Comment: 11 pages, 26 (sub)figure

    Fractal Stability Border in Plane Couette Flow

    Full text link
    We study the dynamics of localised perturbations in plane Couette flow with periodic lateral boundary conditions. For small Reynolds number and small amplitude of the initial state the perturbation decays on a viscous time scale tRet \propto Re. For Reynolds number larger than about 200, chaotic transients appear with life times longer than the viscous one. Depending on the type of the perturbation isolated initial conditions with infinite life time appear for Reynolds numbers larger than about 270--320. In this third regime, the life time as a function of Reynolds number and amplitude is fractal. These results suggest that in the transition region the turbulent dynamics is characterised by a chaotic repeller rather than an attractor.Comment: 4 pages, Latex, 4 eps-figures, submitted to Phys. Rev. Le

    Fragment Production in Non-central Collisions of Intermediate Energy Heavy Ions

    Full text link
    The defining characteristics of fragment emission resulting from the non-central collision of 114Cd ions with 92Mo target nuclei at E/A = 50 MeV are presented. Charge correlations and average relative velocities for mid-velocity fragment emission exhibit significant differences when compared to standard statistical decay. These differences associated with similar velocity dissipation are indicative of the influence of the entrance channel dynamics on the fragment production process

    Travelling waves in pipe flow

    Full text link
    A family of three-dimensional travelling waves for flow through a pipe of circular cross section is identified. The travelling waves are dominated by pairs of downstream vortices and streaks. They originate in saddle-node bifurcations at Reynolds numbers as low as 1250. All states are immediately unstable. Their dynamical significance is that they provide a skeleton for the formation of a chaotic saddle that can explain the intermittent transition to turbulence and the sensitive dependence on initial conditions in this shear flow.Comment: 4 pages, 5 figure

    Space and Time pattern of mid-velocity IMF emission in peripheral heavy-ion collisions at Fermi energies

    Full text link
    The emission pattern in the V_perp - V_par plane of Intermediate Mass Fragments with Z=3-7 (IMF) has been studied in the collision 116Sn + 93Nb at 29.5 AMeV as a function of the Total Kinetic Energy Loss of the reaction. This pattern shows that for peripheral reactions most of IMF's are emitted at mid-velocity. Coulomb trajectory calculations demonstrate that these IMF's are produced in the early stages of the reaction and shed light on geometrical details of these emissions, suggesting that the IMF's originate both from the neck and the surface of the interacting nuclei.Comment: 4 pages, 3 figures, RevTex 3.1, submitted to Phys. Rev. Letter

    How does flow in a pipe become turbulent?

    Full text link
    The transition to turbulence in pipe flow does not follow the scenario familiar from Rayleigh-Benard or Taylor-Couette flow since the laminar profile is stable against infinitesimal perturbations for all Reynolds numbers. Moreover, even when the flow speed is high enough and the perturbation sufficiently strong such that turbulent flow is established, it can return to the laminar state without any indication of the imminent decay. In this parameter range, the lifetimes of perturbations show a sensitive dependence on initial conditions and an exponential distribution. The turbulence seems to be supported by three-dimensional travelling waves which appear transiently in the flow field. The boundary between laminar and turbulent dynamics is formed by the stable manifold of an invariant chaotic state. We will also discuss the relation between observations in short, periodically continued domains, and the dynamics in fully extended puffs.Comment: for the proceedings of statphys 2

    Basin boundary, edge of chaos, and edge state in a two-dimensional model

    Full text link
    In shear flows like pipe flow and plane Couette flow there is an extended range of parameters where linearly stable laminar flow coexists with a transient turbulent dynamics. When increasing the amplitude of a perturbation on top of the laminar flow, one notes a a qualitative change in its lifetime, from smoothly varying and short one on the laminar side to sensitively dependent on initial conditions and long on the turbulent side. The point of transition defines a point on the edge of chaos. Since it is defined via the lifetimes, the edge of chaos can also be used in situations when the turbulence is not persistent. It then generalises the concept of basin boundaries, which separate two coexisting attractors, to cases where the dynamics on one side shows transient chaos and almost all trajectories eventually end up on the other side. In this paper we analyse a two-dimensional map which captures many of the features identified in laboratory experiments and direct numerical simulations of hydrodynamic flows. The analysis of the map shows that different dynamical situations in the edge of chaos can be combined with different dynamical situations in the turbulent region. Consequently, the model can be used to develop and test further characterisations that are also applicable to realistic flows.Comment: 24 pages, 9 color figure

    Charge correlations and dynamical instabilities in the multifragment emission process

    Full text link
    A new, sensitive method allows one to search for the enhancement of events with nearly equal-sized fragments as predicted by theoretical calculations based on volume or surface instabilities. Simulations have been performed to investigate the sensitivity of the procedure. Experimentally, charge correlations of intermediate mass fragments emitted from heavy ion reactions at intermediate energies have been studied. No evidence for a preferred breakup into equal-sized fragments has been found.Comment: 12 pages, TeX type, psfig, submitted to Phys. Rev. Lett, also available at http://csa5.lbl.gov/moretto/ps/zcor_pp.p

    Direct simulation of a permeable membrane

    No full text
    Cellular automata are used to compute flow thru a permeable membrane. Scattering centers constitute the membrane. This is in marked contrast to the approach of classical hydrodynamics which represents a membrane by a boundary condition. With the scattering centers we obtain different, but more plausible results indicating that simple diffusion is the dominating process in a porous layer. We have thus a case where cellular automata show superiority over the classical methods of theoretical hydrodynamics
    corecore