Parents' views of self-management for children with moderate to severe persistent asthma

AbstractObjectivesChildren with moderate to severe persistent asthma, including those with asthma attacks more than once daily, asthma symptoms at night more than once a week, or asthma attacks that affect activities and sleep, may have irregular and recurrent symptoms until adolescence. Such symptoms may affect quality of life and even cause death. This study explored the self-management experiences of children with asthma in Hualien City, Taiwan, based on the views expressed by their parents.Materials and methodsThis study used a qualitative inquiry of 15 parents of children with asthma, in order to understand the children's self-management experiences.ResultsThe findings from this study, as derived from content analysis, showed the following six domains of self-management: (1) knowledge of asthma; (2) use of asthma medications; (3) issues related to physical exercise; (4) self-care in daily life; (5) prevention and handling of asthmatic episodes; and (6) other issues related to asthma.ConclusionThe results of the study can help health professionals understand the self-management experiences of families who have a child with persistent asthma, which in turn could provide appropriate guidelines and valuable information for development of self-management programs for children with asthma

SOHSite: incorporating evolutionary information and physicochemical properties to identify protein S-sulfenylation sites

Distribution of KEGG pathway annotations for S-sulfenylated proteins. (DOCX 15 kb

Machine Learning-based Indoor Positioning Systems Using Multi-Channel Information

The received signal strength indicator (RSSI) is a metric of the power measured by a sensor in a receiver. Many indoor positioning technologies use RSSI to locate objects in indoor environments. Their positioning accuracy is significantly affected by reflection and absorption from walls, and by non-stationary objects such as doors and people. Therefore, it is necessary to increase transceivers in the environment to reduce positioning errors. This paper proposes an indoor positioning technology that uses the machine learning algorithm of channel state information (CSI) combined with fingerprinting. The experimental results showed that the proposed method outperformed traditional RSSI-based localization systems in terms of average positioning accuracy up to 6.13% and 54.79% for random forest (RF) and back propagation neural networks (BPNN), respectively

Machine Learning-based Indoor Positioning Systems Using Multi-Channel Information

The received signal strength indicator (RSSI) is a metric of the power measured by a sensor in a receiver. Many indoor positioning technologies use RSSI to locate objects in indoor environments. Their positioning accuracy is significantly affected by reflection and absorption from walls, and by non-stationary objects such as doors and people. Therefore, it is necessary to increase transceivers in the environment to reduce positioning errors. This paper proposes an indoor positioning technology that uses the machine learning algorithm of channel state information (CSI) combined with fingerprinting. The experimental results showed that the proposed method outperformed traditional RSSI-based localization systems in terms of average positioning accuracy up to 6.13% and 54.79% for random forest (RF) and back propagation neural networks (BPNN), respectively

THE STUDY OF SHOULDER INTERNAL AND EXTERNAL ROTATION STRENGTH IN COLLEGE BASEBALL PLAYERS

The purpose of this study was to investigate the different of dominant arm shoulder rotation torque between the baseball pitchers, infielders, and ouffielders. Participants were 27 first-level collegiate baseball players, including 9 pitchers, 10 infielders, 8 outfielders. A Biodex lsokinetic Dynamometer was used for estimation of shoulder muscle strength. This system's test velocity was set at 60 "Is and the range of motion of dominant arm shoulder in flexion, abduction, 90' of abduction with external rotation, and 90" abduction with internal rotation. The results indicated that there was no significant different in internal rotation peak torque and ERllR ratio between pitchers, infielders, and outfielders. There was significantly different in external rotation peak torque. The infielders and ouffielders possess greater external rotation peak torque than pitchers

The incidence of symptomatic venous thromboembolism following hip fractures with or without surgery in Taiwan

AbstractBackgroundInformation on the incidence of venous thromboembolism (VTE) following hip fractures in Asia is rare. This study will investigate the epidemiology of symptomatic VTE in Taiwanese patients experiencing hip fractures.Methods and resultsWe used Taiwan's National Health Insurance Research Database to retrospectively identify patients (≧45years) who experienced hip fractures from 1998 to 2007 and were followed up for 3months after the discharge. Logistic regression analysis determined the independent risk factors of symptomatic VTE after the fractures. We identified 134,034 patients (mean age: 76.2±9.7years; female: 57.8%) who experienced hip fractures, 83.2% of whom underwent hip surgery. The overall pharmacological thromboprophylaxis rate was 2.7%. The mean length of stay was 11.3±7.9days. The 3-month cumulative incidence of symptomatic VTE was 77 events per 10,000 persons. Multivariate analysis showed that previous DVT, previous PE, varicose veins, cancer, heart failure, renal insufficiency, and older age were independent risk factors of developing VTE.ConclusionsThe incidence of symptomatic VTE after hip fractures is low in Taiwan. Patients rarely received pharmacological thromboprophylaxis following hip fractures. Universal thromboprophylaxis for patients experiencing hip fractures was not necessary in Taiwan, but it should be considered in high-risk populations

Isolated tracheal injury after whiplash

AbstractWhiplash, a sudden acceleration–deceleration movement that can cause diverse symptoms such as neck pain, cervicogenic headache, restricted neck movement, tingling of the arms (central cord syndrome), and dizziness. However, laryngotracheal injuries after whiplash are extremely rare. We report the case of a 25-year-old Taiwanese female who presented to the emergency department with severe posterior midline neck pain after a rear-end motorcycle collision. Her C-spine X-ray showed no definite fracture; furthermore, her neck noncontrast-enhanced CT scan revealed paratracheal free air. She was discharged uneventfully after a 12-h observation period. Laryngotracheal injuries after whiplash, a hyperextension–hyperflexion movement, are potentially life-threatening and could lead to airway obstruction. Such injuries should not be overlooked. To the best of our knowledge, this is the first case report of isolated laryngotracheal injury after whiplash

Efficacy of a paper-based interleukin-6 test strip combined with a spectrum-based optical reader for sequential monitoring and early recognition of respiratory failure in elderly pneumonia—a pilot study

Introduction: Community-acquired pneumonia (CAP) is lethal in elderly individuals who are more vulnerable to respiratory failure and require more emergency ventilation support than younger individuals. Interleukin-6 (IL-6) plays a crucial role and has predictive value in CAP; high serum IL-6 concentrations in adults are associated with high respiratory failure and mortality rates. Early detection of IL-6 concentrations can facilitate the timely stratification of patients at risk of acute respiratory failure. However, conventional enzyme-linked immunosorbent assay (ELISA) IL-6 measurement is laborious and time-consuming.Methods: The IL-6 rapid diagnostic system combined with a lateral flow immunoassay-based (LFA-based) IL-6 test strip and a spectrum-based optical reader is a novel tool developed for rapid and sequential bedside measurements of serum IL-6 concentrations. Here, we evaluated the correlation between the IL-6 rapid diagnostic system and the ELISA and the efficacy of the system in stratifying high-risk elderly patients with CAP. Thirty-six elderly patients (median age: 86.5 years; range: 65–97 years) with CAP were enrolled. CAP diagnosis was established based on the Infectious Diseases Society of America (IDSA) criteria. The severity of pneumonia was assessed using the CURB-65 score and Pneumonia Severity Index (PSI). IL-6 concentration was measured twice within 24 h of admission.Results: The primary endpoint variable was respiratory failure requiring invasive mechanical or non-invasive ventilation support after admission. IL-6 rapid diagnostic readouts correlated with ELISA results (p < 0.0001) for 30 samples. Patients were predominantly male and bedridden (69.4%). Ten patients (27.7%) experienced respiratory failure during admission, and five (13.9%) died of pneumonia. Respiratory failure was associated with a higher mortality rate (p = 0.015). Decreased serum IL-6 concentration within 24 h after admission indicated a lower risk of developing respiratory failure in the later admission course (Receiver Operating Characteristic [ROC] curve = 0.696).Conclusion: Sequential IL-6 measurements with the IL-6 rapid diagnostic system might be useful in early clinical risk assessment and severity stratification of elderly patients with pneumonia. This system is a potential point-of-care diagnostic device for sequential serum IL-6 measurements that can be applied in variable healthcare systems