7,558 research outputs found

    Optimal Property Management Strategies

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    This paper examines the optimal operation strategies for income properties. Specifically, the rental rate and the operating expense should be set at levels to maximize the return on investment. The results suggest that for a given demand curve of a specific rental property, there exist optimal levels of the income ratio, the operating expense ratio, and the vacancy rate. With a Cobb-Douglas demand curve, we derived closed form solutions of these optimal ratios for a given income property. The relevant local comparative statics of these ratios also are derived. These comparative statics also provide insight into the optimal building size and optimal rehabilitation decisions. An empirical case study was conducted to demonstrate how the model can be applied in real life situations.Rental Property, Vacancy Rate; Operating Strategy, Profit Optimization

    Rehabilitation of soft tissue injuries of the hip and pelvis

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    Soft tissue injuries of the hip and pelvis are common among athletes and can result in significant time loss from sports participation. Rehabilitation of athletes with injuries such as adductor strain, iliopsoas syndrome, and gluteal tendinopathy starts with identification of known risk factors for injury and comprehensive evaluation of the entire kinetic chain. Complex anatomy and overlapping pathologies often make it difficult to determine the primary cause of the pain and dysfunction. The purpose of this clinical commentary is to present an impairment-based, stepwise progression in evaluation and treatment of several common soft tissue injuries of the hip and pelvis. LEVEL OF EVIDENCE: 5

    Fertilisation and early developmental barriers to hybridisation in field crickets

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    This is the final version of the article. Available from the publisher via the DOI in this record.BACKGROUND: Post-mating interactions between the reproductive traits and gametes of mating individuals and among their genes within zygotes are invariably complex, providing multiple opportunities for reproduction to go awry. These interactions have the potential to act as barriers to gene flow between species, and may be important in the process of speciation. There are multiple post-mating barriers to interbreeding between the hybridising field crickets Gryllus bimaculatus and G. campestris. Female G. bimaculatus preferentially store sperm from conspecific males when mated to both conspecific and heterospecific partners. Additionally, conspecific males sire an even greater proportion of offspring than would be predicted from their sperm's representation in the spermatheca. The nature of these post-sperm-storage barriers to hybridisation are unknown. We use a fluorescent staining technique to determine whether barriers occur prior to, or during embryo development. RESULTS: We show that eggs laid by G. bimaculatus females mated to G. campestris males are less likely to begin embryogenesis than eggs from conspecific mating pairs. Of the eggs that are successfully fertilised and start to develop, those from heterospecific mating pairs are more likely to arrest early, prior to blastoderm formation. We find evidence for bimodal variation among egg clutches in the number of developing embryos that subsequently arrest, indicating that there is genetic variation for incompatibility between mating individuals. In contrast to the pattern of early embryonic mortality, those hybrids reaching advanced stages of embryogenesis have survival rates equal to that of embryos from conspecific mating pairs. CONCLUSIONS: Post-sperm-storage barriers to hybridisation show evidence of genetic polymorphism. They are sufficiently large, that if the species interbreed where they are sympatric, these barriers could play a role in the maintenance of reproductive isolation between them. The number of eggs that fail to develop represents a substantial cost of hybridization to G. bimaculatus females, and this cost could reinforce the evolution of barriers occurring earlier in the reproductive process.This work was supported by the European Social Fund and the Natural Environment Research Council

    Illness Severity among Non-English, Non-Spanish Speaking Patients in a Public Emergency Department

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    Background: Patients with limited English proficiency (LEP) have poor health outcomes compared to English proficient patients. Most studies on language proficiency and health disparities focus on Spanish. Objective: This study examines whether non-Spanish speaking LEP patients experience greater disparities than Spanish speaking LEP patients by comparing disease acuity and language proficiency in an emergency department. Design: This is a retrospective case-control study from November 2010 to February 2012 comparing differences between non-English non-Spanish (NENS) speaking patients to English speaking patients with differences between Spanish speaking and English speaking patients. Main outcomes: Primary endpoints include the emergency severity index (ESI) score, area of triage, days in hospital, and the rates of admission, in-hospital surgery, intensive care unit admission, and all-cause mortality. Results: Among all of the study patients, the average age was 55.1 (+/- 12.4). Comparing the NENS sample to the English sample yielded differences in surgery rates (NENS 11.3%, English 1.9%, p=0.002), admission rates (NENS 38.8%, English 24.7%, p=0.025), and days in hospital (NENS 2.49 +/-5.43, English 1.93+/-8.56, p Conclusions and relevance: We were able to demonstrate greater healthcare needs among NENS patients compared to the other two groups. The NENS patients were more likely to be admitted, have surgery, and stay longer than those speaking English or Spanish. These findings are important because they suggest further research, awareness of these disparities by healthcare providers, and public health interventions focusing on this population are warranted

    Athletic pubalgia and associated rehabilitation

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    BACKGROUND: Evaluation and treatment of groin pain in athletes is challenging. The anatomy is complex, and multiple pathologies often coexist. Different pathologies may cause similar symptoms, and many systems can refer pain to the groin. Many athletes with groin pain have tried prolonged rest and various treatment regimens, and received differing opinions as to the cause of their pain. The rehabilitation specialist is often given a non-specific referral of groin pain or sports hernia. The cause of pain could be as simple as the effects of an adductor strain, or as complex as athletic pubalgia or inguinal disruption. The term sports hernia is starting to be replaced with more specific terms that better describe the injury. Inguinal disruption is used to describe the syndromes related to the injury of the inguinal canal soft tissue environs ultimately causing the pain syndrome. The term athletic pubalgia is used to describe the disruption and/or separation of the more medial common aponeurosis from the pubis, usually with some degree of adductor tendon pathology. TREATMENT: Both non-operative and post-operative treatment options share the goal of returning the athlete back to pain free activity. There is little research available to reference for rehabilitation guidelines and creation of a plan of care. Although each surgeon has their own specific set of post-operative guidelines, some common concepts are consistent among most surgeons. Effective rehabilitation of the high level athlete to pain free return to play requires addressing the differences in the biomechanics of the dysfunction when comparing athletic pubalgia and inguinal disruption. CONCLUSION: Proper evaluation and diagnostic skills for identifying and specifying the difference between athletic pubalgia and inguinal disruption allows for an excellent and efficient rehabilitative plan of care. Progression through the rehabilitative stages whether non-operative or post-operative allows for a focused rehabilitative program. As more information is obtained through MRI imaging and the diagnosis and treatment of inguinal disruption and athletic pubalgia becomes increasingly frequent, more research is warranted in this field to better improve the evidence based practice and rehabilitation of patients. LEVELS OF EVIDENCE: 5

    Mitochondrial genomes and thousands of ultraconserved elements resolve the taxonomy and historical biogeography of the Euphonia and Chlorophonia finches (Passeriformes: Fringillidae)

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    © 2020 American Ornithological Society. Relationships of the Neotropical finches in the genera Euphonia and Chlorophonia (Fringillidae: Euphoniinae) have been clarified by recent molecular studies, but species-level relationships within this group have not been thoroughly addressed. In this study, we sampled specimens representing every recognized species of these genera, in addition to 2 outgroup taxa, and used target enrichment to sequence thousands of ultraconserved element (UCE) loci, as well as mitochondrial DNA reconstructed from off-target reads, from each specimen to infer these relationships. We constructed both concatenation and coalescent-based estimates of phylogeny from this dataset using matrices of varying levels of completeness, and we generated a time-scaled ultrametric tree using a recently published fossil-based external calibration. We found uniformly strong support for a monophyletic subfamily Euphoniinae and genus Chlorophonia, but a paraphyletic Euphonia across UCEs and mitochondrial genomes. Otherwise, our inferred relationships were largely concordant with previous studies. Our time-tree indicated a stem divergence time of 13.8 million years ago for this lineage, followed by a relatively young crown age of only 7.1 myr. Reconstructions of biogeographic history based on this tree suggest a South American origin for crown Euphoniinae, possibly resulting from a transoceanic dispersal event from the Eastern Hemisphere, followed by 2 dispersal events into the Caribbean and as many as 6 invasions of North America coinciding with recent estimates of the age at which the Isthmus of Panama had completely formed. We recommend splitting Euphonia and resurrecting the genus Cyanophonia for the 3 blue-hooded species more closely related to Chlorophonia. Based on our results, we suspect that there is undescribed species-level diversity in at least one, possibly many, widespread and phenotypically diverse species

    Evolution of Conversations in the Age of Email Overload

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    Email is a ubiquitous communications tool in the workplace and plays an important role in social interactions. Previous studies of email were largely based on surveys and limited to relatively small populations of email users within organizations. In this paper, we report results of a large-scale study of more than 2 million users exchanging 16 billion emails over several months. We quantitatively characterize the replying behavior in conversations within pairs of users. In particular, we study the time it takes the user to reply to a received message and the length of the reply sent. We consider a variety of factors that affect the reply time and length, such as the stage of the conversation, user demographics, and use of portable devices. In addition, we study how increasing load affects emailing behavior. We find that as users receive more email messages in a day, they reply to a smaller fraction of them, using shorter replies. However, their responsiveness remains intact, and they may even reply to emails faster. Finally, we predict the time to reply, length of reply, and whether the reply ends a conversation. We demonstrate considerable improvement over the baseline in all three prediction tasks, showing the significant role that the factors that we uncover play, in determining replying behavior. We rank these factors based on their predictive power. Our findings have important implications for understanding human behavior and designing better email management applications for tasks like ranking unread emails.Comment: 11 page, 24th International World Wide Web Conferenc

    Marine Evidence-based Sensitivity Assessment (MarESA) – A Guide

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    The Marine Evidence-based Sensitivity Assessment (MarESA) methodology was developed by the Marine Life Information Network (MarLIN) team at the Marine Biological Association of the UK. The following guide details the approach, its assumptions, and its application to sensitivity assessment. The guide discusses: • key terms used in sensitivity assessment; • the definitions and terms used in the MarESA approach; • its assumptions; • the definition of resistance, resilience and sensitivity; • the definition of pressures and their benchmarks; • the step by step process by which the possible sensitivity of each feature (habitat, biotope or species) to each pressure is assessed; • the interpretation and application of evidence to sensitivity assessments on a pressure by pressure basis; and • limitations in the application of sensitivity assessments in management. The MarESA methodology provides a systematic process to compile and assess the best available scientific evidence to determine each sensitivity assessment. The evidence used is documented throughout the process to provide an audit trail to explain each sensitivity assessment. Unlike other expert-based approaches, this means that the MarESA assessments can be repeated and updated. The resultant 'evidence base' is the ultimate source of information for the application of the sensitivity assessments to management and planning decisions. The MarESA dataset and MarLIN website represent the largest review of the potential effects of human activities and natural events on the marine and coastal habitats of the North East Atlantic yet undertaken

    IRAS 11590-6452 in BHR 71 - a binary protostellar system?

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    New AAT near-infrared and SEST 12CO J=2-1 observations are combined with existing ISO mid-infrared and ATCA cm radio continuum observations to examine the protostellar content of the Bok globule BHR 71. Together with observations of Herbig-Haro objects, these data show: (1) Two protostellar sources, IRS1 and IRS2, with a separation of ~17 arcsec (3400 AU) are located within BHR 71. (2) Each protostar is driving its own molecular outflow. The outflow from IRS1 is much larger in extent, is more massive, and dominates the CO emission. (3) Both protostars are associated with Herbig-Haro objects and shock excited 2.122 micron H2 v=1-0S(1) emission, which coincide spatially with their CO outflows. (4) IRS1 is associated with cm continuum emission, with a flat or rising spectrum which is consistent with free-free emission, a signpost of protostellar origin.Comment: 12 pages, 2 figures (colour), accepted by ApJ Letters. See also http://cfa-www.harvard.edu/~bourke
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