Restoring Trust Relationships within Collaborative Digital Preservation Federations

4th International Conference on Open RepositoriesThis presentation was part of the session : Conference PresentationsDate: 2009-05-19 01:00 PM – 02:30 PMThe authors extend their process for creating and establishing trust relationships to include steps for restoring trust relationships after catastrophic events. Part of this model will include best practices for business continuity relationships and will integrate trust models from Holland and Lockett (1998) and Ring and Van de Ven (1994) and how they can be applied to a process for trust restoration after periods of disaster or critical data loss. These models provide key frameworks for understanding how trust can be utilized for collaborative start points as well as for collaborative recovery points from physical natural disaster or critical data loss

Addressing the challenges of modeling the scattering from bottlebrush polymers in solution

Small‐angle scattering measurements of complex macromolecules in solution are used to establish relationships between chemical structure and conformational properties. Interpretation of the scattering data requires an inverse approach where a model is chosen and the simulated scattering intensity from that model is iterated to match the experimental scattering intensity. This raises challenges in the case where the model is an imperfect approximation of the underlying structure, or where there are significant correlations between model parameters. We examine three bottlebrush polymers (consisting of polynorbornene backbone and polystyrene side chains) in a good solvent using a model commonly applied to this class of polymers: the flexible cylinder model. Applying a series of constrained Monte‐Carlo Markov Chain analyses demonstrates the severity of the correlations between key parameters and the presence of multiple close minima in the goodness of fit space. We demonstrate that a shape‐agnostic model can fit the scattering with significantly reduced parameter correlations and less potential for complex, multimodal parameter spaces. We provide recommendations to improve the analysis of complex macromolecules in solution, highlighting the value of Bayesian methods. This approach provides richer information for understanding parameter sensitivity compared to methods which produce a single, best fit

Laser-induced fluorescence studies of HfF+ produced by autoionization

Autoionization of Rydberg states of HfF, prepared using the optical-optical double resonance (OODR) technique, holds promise to create HfF+ in a particular Zeeman level of a rovibronic state for an electron electric dipole moment (eEDM) search. We characterize a vibronic band of Rydberg HfF at 54 cm-1 above the lowest ionization threshold and directly probe the state of the ions formed from this vibronic band by performing laser-induced fluorescence (LIF) on the ions. The Rydberg HfF molecules show a propensity to decay into only a few ion rotational states of a given parity and are found to preserve their orientation qualitatively upon autoionization. We show empirically that we can create 30% of the total ion yield in a particular |J+,M+> state and present a simplified model describing autoionization from a given Rydberg state that assumes no angular dynamics.Comment: 8 pages, 5 figure

CM5, a pre-Swarm comprehensive geomagnetic field model derived from over 12yr of CHAMP, Ørsted, SAC-C and observatory data

A comprehensive magnetic field model named CM5 has been derived from CHAMP, Ørsted and SAC-C satellite and observatory hourly-means data from 2000 August to 2013 January using the Swarm Level-2 Comprehensive Inversion (CI) algorithm. Swarm is a recently launched constellation of three satellites to map the Earth's magnetic field. The CI technique includes several interesting features such as the bias mitigation scheme known as Selective Infinite Variance Weighting (SIVW), a new treatment for attitude error in satellite vector measurements, and the inclusion of 3-D conductivity for ionospheric induction. SIVW has allowed for a much improved lithospheric field recovery over CM4 by exploiting CHAMP along-track difference data yielding resolution levels up to spherical harmonic degree 107, and has allowed for the successful extraction of the oceanic M2 tidal magnetic field from quiet, nightside data. The 3-D induction now captures anomalous Solar-quiet features in coastal observatory daily records. CM5 provides a satisfactory, continuous description of the major magnetic fields in the near-Earth region over this time span, and its lithospheric, ionospheric and oceanic M2 tidal constituents may be used as validation tools for future Swarm Level-2 products coming from the CI algorithm and other dedicated product algorithm

Sustainability Models for Digital Preservation Federations

The Library of Congress&rsquo;s National Digital Information Infrastructure and Preservation Program (NDIIPP &ndash; www.digitalpreservation.gov) has brought together a variety of partners over the last few years (2004-2007) to take an in-depth look at various digital preservation technologies and the organizational strategies to implement digital preservation programs (LeFurgy, 2005). This national program has been a success and the Library of Congress plans to extend it through 2010 to develop these partnerships and solidify the sustainability of the preservation initiatives that have emerged. Like many such national programs, NDIIPP is both a benefactor and catalyst of applied and theoretical work on digital preservation being conducted in the United States. This paper will present the sustainability models that have emerged at the international, national, state/regional, and local levels and contrast those with models that have emerged out of the work of the NDIIPP partnership known as the MetaArchiveCooperative (www.metaarchive.org). This overview will address governance issues for federated digital preservation programs that span across unilateral institutional governance.</p

Gp91ds-tat, a Selective NADPH Oxidase Peptide Inhibitor, Increases Blood Nitric Oxide (NO) Bioavailability in Bind Limb Ischemia and Reperfusion (I/R)

I/R injury induces cell death and organ dysfunction in part due to a burst of reactive oxygen species that occurs upon the reintroduction of oxygen into the ischemic area, leading to endothelial dysfunction: decreased blood NO and increased hydrogen peroxide (H2O2 ) levels. We’ve previously shown in isolated rat hearts subjected to I/R injury, gp91ds-tat attenuated cardiac contractile dysfunction and reduced infarct size compared to controls presumably by the inhibition of NADPH oxidase induced superoxide release. Superoxide can quench NO via the formation of peroxynitrite and also be converted to H2O2 in blood. We attempted to confirm this hypothesis using a rat hind limb I/R model that permitted real time measurements of changes in blood NO and H2O2. NO or H2O2 microsensors were inserted into both femoral veins in anesthetized male rats. One limb’s femoral artery/vein is subjected to I(30min)/R(45min) while the other served as a non-ischemic sham. Preliminary results show blood NO release significantly increased by the end of reperfusion in gp91ds-tat treated rats (1.2 mg/kg, MW 2452g/mol, n=5) compared to saline treated rats (n=3;