276 research outputs found
Nucleon axial charge in 2+1 flavor dynamical lattice QCD with domain wall fermions
We present results for the nucleon axial charge g_A at a fixed lattice
spacing of 1/a=1.73(3) GeV using 2+1 flavors of domain wall fermions on size
16^3x32 and 24^3x64lattices (L=1.8 and 2.7 fm) with length 16 in the fifth
dimension. The length of the Monte Carlo trajectory at the lightest m_\pi is
7360 units, including 900 for thermalization. We find finite volume effects are
larger than the pion mass dependence at m_\pi= 330 MeV. We also find that g_A
exhibits a scaling with the single variable m_\pi L which can also be seen in
previous two-flavor domain wall and Wilson fermion calculati ons. Using this
scaling to eliminate the finite-volume effect, we obtain g_A = 1.20(6)(4) at
the physical pion mass, m_\pi = 135 MeV, where the first and second errors are
statistical and systematic. The observed finite-volume scaling also appears in
similar quenched simulations, but disappear when V\ge (2.4 fm)^3. We argue this
is a dynamical quark effect.Comment: 4 pages and 3 figure
First results from 2+1-Flavor Domain Wall QCD: Mass Spectrum, Topology Change and Chiral Symmetry with
We present results for the static interquark potential, light meson and
baryon masses, and light pseudoscalar meson decay constants obtained from
simulations of domain wall QCD with one dynamical flavour approximating the
quark, and two degenerate dynamical flavours with input bare masses ranging
from to approximating the and quarks. We compare these
quantities obtained using the Iwasaki and DBW2 improved gauge actions, and
actions with larger rectangle coefficients, on lattices. We seek
parameter values at which both the chiral symmetry breaking residual mass due
to the finite lattice extent in the fifth dimension and the Monte Carlo time
history for topological charge are acceptable for this set of quark masses at
lattice spacings above 0.1 fm. We find that the Iwasaki gauge action is best,
demonstrating the feasibility of using QCDOC to generate ensembles which are
good representations of the QCD path integral on lattices of up to 3 fm in
spatial extent with lattice spacings in the range 0.09-0.13 fm. Despite large
residual masses and a limited number of sea quark mass values with which to
perform chiral extrapolations, our results for light hadronic physics scale and
agree with experimental measurements within our statistical uncertainties.Comment: RBC and UKQCD Collaborations. 82 pages, 34 figures Typos correcte
Acceleressence: Dark Energy from a Phase Transition at the Seesaw Scale
Simple models are constructed for "acceleressence" dark energy: the latent
heat of a phase transition occurring in a hidden sector governed by the seesaw
mass scale v^2/M_Pl, where v is the electroweak scale and M_Pl the
gravitational mass scale. In our models, the seesaw scale is stabilized by
supersymmetry, implying that the LHC must discover superpartners with a
spectrum that reflects a low scale of fundamental supersymmetry breaking.
Newtonian gravity may be modified by effects arising from the exchange of
fields in the acceleressence sector whose Compton wavelengths are typically of
order the millimeter scale. There are two classes of models. In the first class
the universe is presently in a metastable vacuum and will continue to inflate
until tunneling processes eventually induce a first order transition. In the
simplest such model, the range of the new force is bounded to be larger than 25
microns in the absence of fine-tuning of parameters, and for couplings of order
unity it is expected to be \approx 100 microns. In the second class of models
thermal effects maintain the present vacuum energy of the universe, but on
further cooling, the universe will "soon" smoothly relax to a matter dominated
era. In this case, the range of the new force is also expected to be of order
the millimeter scale or larger, although its strength is uncertain. A firm
prediction of this class of models is the existence of additional energy
density in radiation at the eV era, which can potentially be probed in
precision measurements of the cosmic microwave background. An interesting
possibility is that the transition towards a matter dominated era has occurred
in the very recent past, with the consequence that the universe is currently
decelerating.Comment: 10 pages, references adde
Discovery of mating in the major African livestock pathogen Trypanosoma congolense
The protozoan parasite, Trypanosoma congolense, is one of the most economically important pathogens of livestock in Africa and, through its impact on cattle health and productivity, has a significant effect on human health and well being. Despite the importance of this parasite our knowledge of some of the fundamental biological processes is limited. For example, it is unknown whether mating takes place. In this paper we have taken a population genetics based approach to address this question. The availability of genome sequence of the parasite allowed us to identify polymorphic microsatellite markers, which were used to genotype T. congolense isolates from livestock in a discrete geographical area of The Gambia. The data showed a high level of diversity with a large number of distinct genotypes, but a deficit in heterozygotes. Further analysis identified cryptic genetic subdivision into four sub-populations. In one of these, parasite genotypic diversity could only be explained by the occurrence of frequent mating in T. congolense. These data are completely inconsistent with previous suggestions that the parasite expands asexually in the absence of mating. The discovery of mating in this species of trypanosome has significant consequences for the spread of critical traits, such as drug resistance, as well as for fundamental aspects of the biology and epidemiology of this neglected but economically important pathogen
Baryon Number in Warped GUTs : Model Building and (Dark Matter Related) Phenomenology
In the past year, a new non-supersymmetric framework for electroweak symmetry
breaking (with or without Higgs) involving SU(2)_L * SU(2)_R * U(1)_{B-L} in
higher dimensional warped geometry has been suggested. In this work, we embed
this gauge structure into a GUT such as SO(10) or Pati-Salam. We showed
recently (in hep-ph/0403143) that in a warped GUT, a stable Kaluza-Klein
fermion can arise as a consequence of imposing proton stability. Here, we
specify a complete realistic model where this particle is a weakly interacting
right-handed neutrino, and present a detailed study of this new dark matter
candidate, providing relic density and detection predictions. We discuss
phenomenological aspects associated with the existence of other light (<~ TeV)
KK fermions (related to the neutrino), whose lightness is a direct consequence
of the top quark's heaviness. The AdS/CFT interpretation of this construction
is also presented. Most of our qualitative results do not depend on the nature
of the breaking of the electroweak symmetry provided that it happens near the
TeV brane.Comment: 61 pages, 12 figures; v2: minor changes; v3: Two additional diagrams
in Fig. 10; a numerical factor corrected in section 16.1 (baryogenesis
section), corresponding discussion slightly modified but qualitative results
unchange
Observation of Parity Nonconservation in Moller Scattering
We report a measurement of the parity-violating asymmetry in fixed target
electron-electron (Moller) scattering: A_PV = -175 +/- 30 (stat.) +/- 20
(syst.) parts per billion. This first direct observation of parity
nonconservation in Moller scattering leads to a measurement of the electron's
weak charge at low energy Q^e_W = -0.053 +/- 0.011. This is consistent with the
Standard Model expectation at the current level of precision:
sin^2\theta_W(M_Z)_MSbar = 0.2293 +/- 0.0024 (stat.) +/- 0.0016 (syst.) +/-
0.0006 (theory).Comment: Version 3 is the same as version 2. These versions contain minor text
changes from referee comments and a change in the extracted value of Q^e_W
and sin^2\theta_W due to a change in the theoretical calculation of the
bremsstrahulung correction (ref. 16
Jet Substructure at the Tevatron and LHC: New results, new tools, new benchmarks
In this report we review recent theoretical progress and the latest
experimental results in jet substructure from the Tevatron and the LHC. We
review the status of and outlook for calculation and simulation tools for
studying jet substructure. Following up on the report of the Boost 2010
workshop, we present a new set of benchmark comparisons of substructure
techniques, focusing on the set of variables and grooming methods that are
collectively known as "top taggers". To facilitate further exploration, we have
attempted to collect, harmonise, and publish software implementations of these
techniques.Comment: 53 pages, 17 figures. L. Asquith, S. Rappoccio, C. K. Vermilion,
editors; v2: minor edits from journal revision
A Cytosine Methyltransferase Homologue Is Essential for Sexual Development in Aspergillus nidulans
Background: The genome defense processes RIP (repeat-induced point mutation) in the filamentous fungus Neurospora crassa, and MIP (methylation induced premeiotically) in the fungus Ascobolus immersus depend on proteins with DNA methyltransferase (DMT) domains. Nevertheless, these proteins, RID and Masc1, respectively, have not been demonstrated to have DMT activity. We discovered a close homologue in Aspergillus nidulans, a fungus thought to have no methylation and no genome defense system comparable to RIP or MIP. Principal Findings: We report the cloning and characterization of the DNA methyltransferase homologue A (dmtA) gene from Aspergillus nidulans. We found that the dmtA locus encodes both a sense (dmtA) and an anti-sense transcript (tmdA). Both transcripts are expressed in vegetative, conidial and sexual tissues. We determined that dmtA, but not tmdA, is required for early sexual development and formation of viable ascospores. We also tested if DNA methylation accumulated in any of the dmtA/tmdA mutants we constructed, and found that in both asexual and sexual tissues, these mutants, just like wild-type strains, appear devoid of DNA methylation. Conclusions/Significance: Our results demonstrate that a DMT homologue closely related to proteins implicated in RIP and MIP has an essential developmental function in a fungus that appears to lack both DNA methylation and RIP or MIP. It remains formally possible that DmtA is a bona fide DMT, responsible for trace, undetected DNA methylation that i
Noncanonical Compensation of Zygotic X Transcription in Early Drosophila melanogaster Development Revealed through Single-Embryo RNA-Seq
Mmany genes from the X chromosome are expressed at the same level in female and male embryos during early Drosophila development, prior to the establishment of MSL-mediated dosage compensation, suggesting the existence of a novel mechanism
Gradual transition from mosaic to global DNA methylation patterns during deuterostome evolution
<p>Abstract</p> <p>Background</p> <p>DNA methylation by the Dnmt family occurs in vertebrates and invertebrates, including ascidians, and is thought to play important roles in gene regulation and genome stability, especially in vertebrates. However, the global methylation patterns of vertebrates and invertebrates are distinctive. Whereas almost all CpG sites are methylated in vertebrates, with the exception of those in CpG islands, the ascidian genome contains approximately equal amounts of methylated and unmethylated regions. Curiously, methylation status can be reliably estimated from the local frequency of CpG dinucleotides in the ascidian genome. Methylated and unmethylated regions tend to have few and many CpG sites, respectively, consistent with our knowledge of the methylation status of CpG islands and other regions in mammals. However, DNA methylation patterns and levels in vertebrates and invertebrates have not been analyzed in the same way.</p> <p>Results</p> <p>Using a new computational methodology based on the decomposition of the bimodal distributions of methylated and unmethylated regions, we estimated the extent of the global methylation patterns in a wide range of animals. We then examined the epigenetic changes <it>in silico </it>along the phylogenetic tree. We observed a gradual transition from fractional to global patterns of methylation in deuterostomes, rather than a clear demarcation between vertebrates and invertebrates. When we applied this methodology to six piscine genomes, some of which showed features similar to those of invertebrates.</p> <p>Conclusions</p> <p>The mammalian global DNA methylation pattern was probably not acquired at an early stage of vertebrate evolution, but gradually expanded from that of a more ancient organism.</p
- β¦