56,200 research outputs found

    PROSES PEMBUATAN CASING PADA MESIN PEMERAS KELAPA PARUT

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    Tujuan dari proyek akhir ini adalah untuk mengetahui cara pembuatan mesin pemeras kelapa parut, khususnya dalam pembuatan casing, yaitu metode yang digunakan dengan mengidentifikasi gambar kerja. Dari identifikasi gambar kerja, diperoleh gambaran tentang konstruksi yang akan dibuat. Proses pembuatan casing pemeras kelapa parut meliputi : Melukis bahan, pengurangan volume bahan, perakitan bahan, dan penyempurnaan permukaan. Sedangkan casing yang dibuat dapat dilakukan dengan cara / langkah-langkah sebagai berikut : Membaca gambar kerja, pengukuran, pelukisan, pemotongan, penekukan, pengeboran, perakitan, penyempurnaan permukaan dan finishing.; Sedangkan peralatan yang digunakan dalam proses pembuatan casing terdiri dari : penggores (spidol), mistar baja, mistar siku (penyiku), roll meter, mesin potong (guillotine), gunting tangan, palu, penitik, mesin bor, kikir, tang rivet, kompresor udara dan spray gun.; dan peralatan yang digunakan untuk keselamatan kerja meliputi : wear pack, kaca mata, sepatu safety, sarung tangan dan penutup telinga. Casing yang dibuat menggunakan bahan plat eysser dengan ketebalan 0,8 mm. Ukuran masing-masing casing yang di buat antara lain, yaitu: casing atas ( tutup box ) dengan ukuran 370 x 350 x 0,8 mm dan casing atas bagian dalam (stainlles steel) dengan ukuran 370 x 350 x 0,8 mm, casing bagian depan, sisi kanan dan bagian sisi kiri dengan ukuran 750 x 350 x 0,8 mm, sedangkan casing belakang bagian atas dengan ukuran 585 x 350 x 0,8 mm dan casing belakang bagian bawah tutup mesin dengan ukuran 330 x 160 x 0,8 mm. Setelah dilakukan uji kinerja di dapatkan hasil bahwa mesin pemeras kelapa parut dapat memproduksi santan sebanyak ± 6 liter/20 menit

    Authors' reply on aspirin for primary prevention.

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    Self similar sets, entropy and additive combinatorics

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    This article is an exposition of recent results on self-similar sets, asserting that if the dimension is smaller than the trivial upper bound then there are almost overlaps between cylinders. We give a heuristic derivation of the theorem using elementary arguments about covering numbers. We also give a short introduction to additive combinatorics, focusing on inverse theorems, which play a pivotal role in the proof. Our elementary approach avoids many of the technicalities in the original proof but also falls short of a complete proof. In the last section we discuss how the heuristic argument is turned into a rigorous one.Comment: 21 pages, 2 figures; submitted to Proceedings of AFRT 2012. v5: more typos correcte

    On Flux Quantization in F-Theory II: Unitary and Symplectic Gauge Groups

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    We study the quantization of the M-theory G-flux on elliptically fibered Calabi-Yau fourfolds with singularities giving rise to unitary and symplectic gauge groups. We seek and find its relation to the Freed-Witten quantization of worldvolume fluxes on 7-branes in type IIB orientifold compactifications on Calabi-Yau threefolds. By explicitly constructing the appropriate four-cycles on which to calculate the periods of the second Chern class of the fourfolds, we find that there is a half-integral shift in the quantization of G-flux whenever the corresponding dual 7-brane is wrapped on a non-spin submanifold. This correspondence of quantizations holds for all unitary and symplectic gauge groups, except for SU(3), which behaves mysteriously. We also perform our analysis in the case where, in addition to the aforementioned gauge groups, there is also a 'flavor' U(1)-gauge group.Comment: 33 pages, 4 figure

    Salivary biomarker development using genomic, proteomic and metabolomic approaches.

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    The use of saliva as a diagnostic sample provides a non-invasive, cost-efficient method of sample collection for disease screening without the need for highly trained professionals. Saliva collection is far more practical and safe compared with invasive methods of sample collection, because of the infection risk from contaminated needles during, for example, blood sampling. Furthermore, the use of saliva could increase the availability of accurate diagnostics for remote and impoverished regions. However, the development of salivary diagnostics has required technical innovation to allow stabilization and detection of analytes in the complex molecular mixture that is saliva. The recent development of cost-effective room temperature analyte stabilization methods, nucleic acid pre-amplification techniques and direct saliva transcriptomic analysis have allowed accurate detection and quantification of transcripts found in saliva. Novel protein stabilization methods have also facilitated improved proteomic analyses. Although candidate biomarkers have been discovered using epigenetic, transcriptomic, proteomic and metabolomic approaches, transcriptomic analyses have so far achieved the most progress in terms of sensitivity and specificity, and progress towards clinical implementation. Here, we review recent developments in salivary diagnostics that have been accomplished using genomic, transcriptomic, proteomic and metabolomic approaches

    Comparison of Different Boost Transformations for the Calculation of Form Factors in Relativistic Quantum Mechanics

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    The effect of different boost expressions, pertinent to the instant, front and point forms of relativistic quantum mechanics, is considered for the calculation of the ground-state form factor of a two-body system in simple scalar models. Results with a Galilean boost as well as an explicitly covariant calculation based on the Bethe-Salpeter approach are given for comparison. It is found that the present so-called point-form calculations of form factors strongly deviate from all the other ones. This suggests that the formalism which underlies them requires further elaboration. A proposition in this sense is made.Comment: Invited talk given at the 18th European Conference on Few-Body Problems in Physics, Bled, Slovenia, 8-14 Sep 2002. Submitted to Few Body Syst.Supp

    Axonal projections of Renshaw cells in the thoracic spinal cord

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    Renshaw cells are widely distributed in all segments of the spinal cord, but detailed morphological studies of these cells and their axonal branching patterns have only been made for lumbosacral segments. For these, a characteristic distribution of terminals was reported, including extensive collateralization within 1-2 mm of the soma, but then more restricted collaterals given off at intervals from the funicular axon. Previous authors have suggested that the projections close to the soma serve inhibition of motoneurons (known to be greatest for the motor nuclei providing the Renshaw cell excitation) but that the distant projections serve mainly the inhibition of other neurons. However, in thoracic segments, inhibition of motoneurons is known to occur over two to three segments (20-40 mm) from the presumed somatic locations of the Renshaw cells. Here, we report the first detailed morphological study of Renshaw cell axons outside the lumbosacral segments, which investigated whether this different distribution of motoneuron inhibition is reflected in a different pattern of Renshaw cell terminations. Four Renshaw cells in T7 or T8 segments were intracellularly labeled with neurobiotin in anesthetized cats and their axons traced for distances ≥6 mm from the somata. The only morphological difference detected within this distance in comparison with Renshaw cells in the lumbosacral cord was a minimal taper in the funicular axons, where in the lumbosacral cord this is pronounced. Patterns of termination were virtually identical to those in the lumbosacral segments, so we conclude that these patterns are unrelated to the pattern of motoneuronal inhibition

    A kinematic and computational study of leech crawling: Support for a CPG based on travelling waves of excitation.

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    Many well characterized central pattern generators (CPGs) underlie behaviors (e.g., swimming, flight, heartbeat) that require regular rhythmicity and strict phase relationships. Here, we examine the organization of a CPG for leech crawling, a behavior whose success depends more on its flexibility than on its precise coordination. We examined the organization of this CPG by first characterizing the kinematics of crawling steps in normal and surgically manipulated animals, then by exploring its features in a simple neuronal model. The behavioral observations revealed the following. (1) Intersegmental coordination varied considerably with step duration, whereas the rates of elongation and contraction within individual segments were relatively constant. (2) Steps were generated in the absence of both head and tail brains, implying that midbody ganglia contain a CPG for step production. (3) Removal of sensory feedback did not affect step coordination or timing. (4) Imposed stretch greatly lengthened transitions between elongation and contraction, indicating that sensory pathways feed back onto the CPG. A simple model reproduced essential features of the observed kinematics. This model consisted of an oscillator that initiates propagating segmental waves of activity in excitatory neuronal chains, along with a parallel descending projection; together, these pathways could produce the observed intersegmental lags, coordination between phases, and step duration. We suggest that the proposed model is well suited to be modified on a step-by-step basis and that crawling may differ substantially from other described CPGs, such as that for swimming in segmented animals, where individual segments produce oscillations that are strongly phase-locked to one another

    Associations of plasma fibrinogen and factor VII clotting activity with coronary heart disease and stroke: prospective cohort study from the screening phase of the Thrombosis Prevention Trial.

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    BACKGROUND: As with 'conventional' risk factors such as cholesterol and smoking, there is a need for large, long-term prospective studies on hemostatic factors. OBJECTIVES: To investigate the prospective relationship of fibrinogen and factor VII clotting activity (FVIIc) with risk of coronary heart disease (CHD) and stroke in a study with a large number of outcomes over a period of 15 years. PATIENTS/METHODS: A cohort of 22 715 men aged 45-69 years was screened for participation in the Thrombosis Prevention Trial. Men were followed up for fatal and non-fatal CHD and stroke events. There were 1515 CHD events (933 CHD deaths) and 391 strokes (180 stroke deaths). Hazard ratios (HRs) and 95% confidence intervals are expressed per standardized increase in log fibrinogen and log FVIIc, adjusting for age, trial treatment group, conventional CHD risk factors and regression dilution bias. RESULTS: Hazard ratios for fibrinogen were 1.52 (1.37-1.70) for all CHD events, and 1.36 (1.09-1.69) for all strokes. Exclusion of events within the first 10 years showed a persistent association between CHD and fibrinogen, with an adjusted HR of 1.93 (1.42-2.64). The HRs for FVIIc, adjusting for age and trial treatment, were 1.07 (1.01-1.12) for all CHD events and 1.07 (0.97-1.20) for all strokes, and the fully adjusted HRs were, respectively, 0.97 (0.84-1.05) and 1.07 (0.85-1.33). CONCLUSIONS: The persisting association between fibrinogen and CHD beyond 10 years may imply a causal effect. There is a small effect of FVIIc on CHD, after adjustment for age and trial treatment, but no association independent of other risk factors

    Circulating markers of arterial thrombosis and age-related maculopathy: a case-control study

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