72 research outputs found

    ANALYSIS OF THE EDGE EFFECT OF SHEAR STRESSES IN THE SHIFT OF A TWO-LAYER BEAM

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    The paper presents a system of resolving equations describing the stress-strain state of multilayer beams and allowing solving a wide range of problems, such as shear, bending, and normal separation for any number of layers. For each of the layers, hypotheses similar to the Kirchhoff - Love hypotheses are introduced. In the proposed model, the layers interact with a contact layer. The contact layer is an anisotropic medium, which can be considered as a “brush” of elastic short rods. For simplicity, it is assumed that the rods are oriented normally to the contact surface. The use of a contact layer allows such problems as infinite tangential stresses at the interface between the layers near the end of the beam and also to solve the problem of determining the concentration of the shearing stresses occurring at the boundaries between the layers and in the corner points, their variation, for example, in the creep process. The main feature of the proposed model is strict satisfaction of the boundary conditions. In view of the complexity of the resolving system of equations, we consider, as an example, the problem of shearing the layers of a double-layer beam. An analytical solution is obtained that allows qualitative analysis of the influence of mechanical and geometric characteristics on the stress-strain state of the design model, calculate the true adhesive strength, and determine the physical characteristics of the contact layer on the basis of experimental data. A numerical example is given for calculating a beam in two variants of model loading, on the basis of which a relationship was established between the true and average adhesive strength, depending on various parameters

    A qualitative study of community perception and acceptance of biological larviciding for malaria mosquito control in rural Burkina Faso

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    Background: Vector and malaria parasite’s rising resistance against pyrethroid-impregnated bed nets and antimalarial drugs highlight the need for additional control measures. Larviciding against malaria vectors is experiencing a renaissance with the availability of environmentally friendly and target species-specific larvicides. In this study,we analyse the perception and acceptability of spraying surface water collections with the biological larvicide Bacillus thuringiensis israelensis in a single health district in Burkina Faso. Methods: A total of 12focus group discussions and 12key informant interviews were performed in 10 rural villages provided with coverage of various larvicide treatments (all breeding sites treated, the most productive breeding sites treated, and untreated control). Results: Respondents’ knowledge about the major risk factors for malaria transmission was generally good. Most interviewees stated they performed personal protective measures against vector mosquitoes including the use of bed nets and sometimes mosquito coils and traditional repellents. The acceptance of larviciding in and around the villages was high and the majority of respondents reported a relief in mosquito nuisance and malarial episodes. There was high interest in the project and demand for future continuation. Conclusion: This study showed that larviciding interventions received positive resonance from the population. People showed a willingness to be involved and financially support the program. The positive environment with high acceptance for larviciding programs would facilitate routine implementation. An essential factor for the future success of such programs would be inclusion in regional or national malaria control guidelines

    Cancer predisposition in mice deficient for the metastasis-associated Mts1(S100A4) gene

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