The PL calibration for Milky Way Cepheids and its implications for the distance scale

The rationale behind recent calibrations of the Cepheid PL relation using the Wesenheit formulation is reviewed and reanalyzed, and it is shown that recent conclusions regarding a possible change in slope of the PL relation for short-period and long-period Cepheids are tied to a pathological distribution of HST calibrators within the instability strip. A recalibration of the period-luminosity relation is obtained using Galactic Cepheids in open clusters and groups, the resulting relationship, described by log L/L_sun = 2.415(+-0.035) + 1.148(+-0.044)log P, exhibiting only the moderate scatter expected from color spread within the instability strip. The relationship is confirmed by Cepheids with HST parallaxes, although without the need for Lutz-Kelker corrections, and in general by Cepheids with revised Hipparcos parallaxes, albeit with concerns about the cited precisions of the latter. A Wesenheit formulation of Wv = -2.259(+-0.083) - 4.185(+-0.103)log P for Galactic Cepheids is tested successfully using Cepheids in the inner regions of the galaxy NGC 4258, confirming the independent geometrical distance established for the galaxy from OH masers. Differences between the extinction properties of interstellar and extragalactic dust may yet play an important role in the further calibration of the Cepheid PL relation and its application to the extragalactic distance scale.Comment: Accepted for Publication (Astrophysics & Space Science

The spectroscopic parameters of sodium cyanide, NaCN (X 1A'), revisited

The study of the rotational spectrum of NaCN (X $^1$A') has recently been extended in frequency and in quantum numbers. Difficulties have been encountered in fitting the transition frequencies within experimental uncertainties. Various trial fits traced the difficulties to the incomplete diagonalization of the Hamiltonian. Employing fewer spectroscopic parameters than before, the transition frequencies could be reproduced within experimental uncertainties on average. Predictions of $a$-type $R$-branch transitions with $K_a \le 7$ up to 570 GHz should be reliable to better than 1 MHz. In addition, modified spectroscopic parameters have been derived for the 13C isotopic species of NaCN.Comment: 5 pages, no figure, J. Mol. Spectrosc., appeared; CDMS links update

The Tensor to Scalar Ratio of Phantom Dark Energy Models

We investigate the anisotropies in the cosmic microwave background in a class of models which possess a positive cosmic energy density but negative pressure, with a constant equation of state w = p/rho < -1. We calculate the temperature and polarization anisotropy spectra for both scalar and tensor perturbations by modifying the publicly available code CMBfast. For a constant initial curvature perturbation or tensor normalization, we have calculated the final anisotropy spectra as a function of the dark energy density and equation of state w and of the scalar and tensor spectral indices. This allows us to calculate the dependence of the tensor-to-scalar ratio on w in a model with phantom dark energy, which may be important for interpreting any future detection of long-wavelength gravitational waves.Comment: 5 pages, 4 figure

Cooperation and Self-Regulation in a Model of Agents Playing Different Games

A simple model for cooperation between "selfish" agents, which play an extended version of the Prisoner's Dilemma(PD) game, in which they use arbitrary payoffs, is presented and studied. A continuous variable, representing the probability of cooperation, $p_k(t) \in$ [0,1], is assigned to each agent $k$ at time $t$. At each time step $t$ a pair of agents, chosen at random, interact by playing the game. The players update their $p_k(t)$ using a criteria based on the comparison of their utilities with the simplest estimate for expected income. The agents have no memory and use strategies not based on direct reciprocity nor 'tags'. Depending on the payoff matrix, the systems self-organizes - after a transient - into stationary states characterized by their average probability of cooperation $\bar{p}_{eq}$ and average equilibrium per-capita-income $\bar{p}_{eq},\bar{U}_\infty$. It turns out that the model exhibit some results that contradict the intuition. In particular, some games which - {\it a priory}- seems to favor defection most, may produce a relatively high degree of cooperation. Conversely, other games, which one would bet that lead to maximum cooperation, indeed are not the optimal for producing cooperation.Comment: 11 pages, 3 figures, keybords: Complex adaptive systems, Agent-based models, Social system

Renal pericytes: regulators of medullary blood flow

Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli. DVR are composed of a continuous endothelium, intercalated with smooth muscle-like cells called pericytes. Pericytes have been shown to alter the diameter of isolated and in situ DVR in response to vasoactive stimuli that are transmitted via a network of autocrine and paracrine signalling pathways. Vasoactive stimuli can be released by neighbouring tubular epithelial, endothelial, red blood cells and neuronal cells in response to changes in NaCl transport and oxygen tension. The experimentally described sensitivity of pericytes to these stimuli strongly suggests their leading role in the phenomenon of MBF autoregulation. Because the debate on autoregulation of MBF fervently continues, we discuss the evidence favouring a physiological role for pericytes in the regulation of MBF and describe their potential role in tubulo-vascular cross-talk in this region of the kidney. Our review also considers current methods used to explore pericyte activity and function in the renal medulla

Urinary Deoxynivalenol Is Correlated with Cereal Intake in Individuals from the United Kingdom

Background Deoxynivalenol (DON) is a toxic fungal metabolite that frequently contaminates cereal crops. DON is toxic to animals, but the effects on humans are poorly understood, in part because exposure estimates are of limited precision. Objectives In this study we used the U.K. adult National Diet and Nutrition Survey to compare 24-hr urinary DON excretion with cereal intake. Methods One hundred subjects were identified for each of the following cereal consumption groups: low (mean, 107 g cereal/day; range, 88–125), medium (mean, 179 g/day; range, 162–195) and high (mean, 300 g/day; range, 276–325). DON was analyzed in 24-hr urine samples by liquid chromatography–mass spectrometry after purification on immunoaffinity columns. Results DON was detected in 296 of 300 (98.7%) urine samples. Cereal intake was significantly associated with urinary DON (p < 0.0005), with the geometric mean urinary levels being 6.55 μg DON/day [95% confidence interval (CI), 5.71–7.53]; 9.63 μg/day (95% CI, 8.39–11.05); and 13.24 μg/day (95% CI, 11.54–15.19) for low-, medium-, and high-intake groups, respectively. In multivariable analysis, wholemeal bread (p < 0.0005), white bread (p < 0.0005), “other” bread (p < 0.0005), buns/cakes (p = 0.003), high-fiber breakfast cereal (p = 0.016), and pasta (p = 0.017) were significantly associated with urinary DON. Wholemeal bread was associated with the greatest percent increase in urinary DON per unit of consumption, but white bread contributed approximately twice as much as wholemeal bread to the urinary DON levels because it was consumed in higher amounts. Conclusion The majority of adults in the United Kingdom appear to be exposed to DON, and on the basis of the urinary levels, we estimate that some individuals may exceed the European Union (EU) recommended maximum tolerable daily intake of 1,000 ng DON/kg (bw). This exposure biomarker will be a valuable tool for biomonitoring as part of surveillance strategies and in etiologic studies of DON and human disease risk

A model of the Universe including Dark Energy accounted for by both a Quintessence Field and a (negative) Cosmological Constant

In this work we present a model of the universe in which dark energy is modelled explicitely with both a dynamical quintessence field and a cosmological constant. Our results confirm the possibility of a future collapsing universe (for a given region of the parameter space), which is necessary for a consistent formulation of string theory and quantum field theory. We have also reproduced the measurements of modulus distance from supernovae with good accuracy.Comment: 11 pages, 4 figures, only the results for the single exponential potential are preserved. One author added. Some changes in the reference section. Submitted to Physical Review

Axion-photon Couplings in Invisible Axion Models

We reexamine the axion-photon couplings in various invisible axion models motivated by the recent proposal of using optical interferometry at the ASST facility in the SSCL to search for axion. We illustrate that the assignment of $U(1)_{PQ}$ charges for the fermion fields plays an important role in determining the couplings. Several simple non-minimal invisible axion models with suppressed and enhanced axion-photon couplings are constructed, respectively. We also discuss the implications of possible new experiments to detect solar axions by conversion to $X$-rays in a static magnetic apparatus tracking the sun.Comment: 14 pages, LaTeX fil

Is the Universe Inflating? Dark Energy and the Future of the Universe

We consider the fate of the observable universe in the light of the discovery of a dark energy component to the cosmic energy budget. We extend results for a cosmological constant to a general dark energy component and examine the constraints on phenomena that may prevent the eternal acceleration of our patch of the universe. We find that the period of accelerated cosmic expansion has not lasted long enough for observations to confirm that we are undergoing inflation; such an observation will be possible when the dark energy density has risen to between 90% and 95% of the critical. The best we can do is make cosmological observations in order to verify the continued presence of dark energy to some high redshift. Having done that, the only possibility that could spoil the conclusion that we are inflating would be the existence of a disturbance (the surface of a true vacuum bubble, for example) that is moving toward us with sufficiently high velocity, but is too far away to be currently observable. Such a disturbance would have to move toward us with speed greater than about 0.8c in order to spoil the late-time inflation of our patch of the universe and yet avoid being detectable.Comment: 7 pages, 7 figure

Limits on the gravity wave contribution to microwave anisotropies

We present limits on the fraction of large angle microwave anisotropies which could come from tensor perturbations. We use the COBE results as well as smaller scale CMB observations, measurements of galaxy correlations, abundances of galaxy clusters, and Lyman alpha absorption cloud statistics. Our aim is to provide conservative limits on the tensor-to-scalar ratio for standard inflationary models. For power-law inflation, for example, we find T/S<0.52 at 95% confidence, with a similar constraint for phi^p potentials. However, for models with tensor amplitude unrelated to the scalar spectral index it is still currently possible to have T/S>1.Comment: 23 pages, 7 figures, accepted for publication in Phys. Rev. D. Calculations extended to blue spectral index, Fig. 6 added, discussion of results expande