Development of textile-based sodium alginate and chitosan hydrogel dressings

TURKOGLU, Gizem Ceylan/0000-0001-5809-0916WOS: 000537894500001Wound healing is a dynamic and complex mechanism. the healing process is affected by many factors, which can be local factors such as wound type, depth of the damaged tissue and bacterial contamination or systemic factors such as patient's age, diet, and diseases. Prior goals should be shortening the wound healing time, ease the pain of the patient and limiting the scar formation. Therefore, the wound should be evaluated profoundly, and the wound care process decided carefully. in this study, textile-hydrogel hybrids were designed to use in mild to moderate exudate wounds. Hydrogels were formed using natural based sodium alginate and chitosan polymers in different cross-linker (PEGDGE) concentrations. To identify the optimum formulation the mechanical properties (hardness, compressibility, adhesiveness, cohesiveness, and elasticity) was examined by texture profile analysis. the gel flow properties were determined by rheological analysis. the suitable formulations for dermal applications were formed on viscose and Tencel nonwovens. Physical features (mass and thickness), pH, absorbency characteristics, transfer properties (air and water vapor permeability), morphologic features (SEM), chemical properties (FT-IR) of textile-based hydrogel dressings were examined

Development of antibacterial textiles by cyclodextrin inclusion complexes of volatile thyme active agents

The study aims to develop wash-resistant antibacterial cotton fabrics without using synthetic chemicals. Therefore, natural active agents of thyme, thymol and carvacrol were selected. The inclusion complexes were formed with beta-cyclodextrin using kneading method which is a simple and reproducible method for the encapsulation with high production yield. Differential scanning calorimeter analysis showed that 1:1 and 1:2 beta-CD: Guest Molecule (M:M) for thymol and carvacrol from different ratios studied has the highest complexation degree as 50% and 100%, respectively. It is also revealed that the volatile agents are retained and showed better thermal stability as a result of complexation. Carvacrol inclusion complexes were found relatively more stable (Zeta potential: -28.2 mV) than thymol complexes with smaller particle sizes (204.9 nm). Chemical structures of the inclusion complexes were revealed with Fourier transform-infrared spectroscopy and nuclear magnetic resonance analyses. The optimum formulations for each active agent were applied to cotton fabrics as per the impregnation method and the capsule treated fabrics were washed 1, 10 and 20 times. The images exhibited the presence of inclusion complexes on the fabrics after 20 washing cycles. Although the antibacterial efficacy of fabrics decreased with increasing washing, the fabrics showed the antibacterial effect after 20 washes against Klebsiella pneumoniae and Staphylococcus aureus. This study showed that the developed products can be an alternative to the other products in the market as the long-lasting fragrant natural antibacterial.Ministry of Science, Industry and Technology, Republic of Turkiye; Organik Kimya Sanayi ve Tic. A.S., Republic of TurkiyeMinistry of Science, Industry and Technology, Republic of Turkiye; Organik Kimya Sanayi ve Tic. A.S., Republic of Turkiy

Micro- and nano-encapsulation of limonene and permethrin for mosquito repellent finishing of cotton textiles

TURKOGLU, Gizem Ceylan/0000-0001-5809-0916; Erkan, Gokhan/0000-0002-2239-9556WOS: 000519929100004The aim of this study was to prepare mosquito repellent textiles. To compare bio-based and synthetic mosquito repellent agents, limonene and permethrin were encapsulated with ethyl cellulose shell. Coacervation was employed, which is a simple and reproducible method for the encapsulation with high production efficiency. Morphological assessment showed that the capsules had smooth surfaces and their shape was spherical. the homogenous size distribution of the capsules was supported by laser diffraction analysis. the capsules showed narrow size distribution and the mean particle size of the optimum formulations for limonene and permethrin was 1 and 1.3 mu m, respectively. the size of the produced capsules was considered suitable for textile applications. the FTIR spectra revealed the similarity of the chemical structure of capsules with shell material. Cotton fabrics were treated separately with limonene and permethrin capsules by padding method. the presence of capsules on the fabrics was determined after 20 washing cycles. Insecticide activity was evaluated against common house mosquitoes (Culex pipiens), with respect to cone bioassay of World Health Organization (WHO). Mosquitoes were tended to stay away from treated fabrics, and mortality rates of mosquitos were noted as 41% and 54% for limonene and permethrin, respectively. Although efficacy of fabrics decreased with increasing washing, the fabrics still showed repellency after 20 washing cycles. This study showed that the developed product might be used as an alternative to the other products in the market for avoiding mosquito-borne diseases

Determination of antioxidant capacity of capsule loaded textiles

WOS: 000405059100010In this study, microcapsules containing alpha-Tocopherol (alpha-TP) have been prepared by complex coacervation technique and applied to cotton fabric by padding method. Characterization of the capsules is determined by scanning electron microscopy, thermogravimetric analysis, fourier transform infrared spectroscopy and particle size measurement. Yield of microencapsulation process is found in the range of 41.63 - 62.20%. Antioxidant capacity of capsule loaded textiles has been examined according to DPPH free radical scavenging method, and alpha-TP existence in ethyl cellulose capsules is found as 65.218 - 330.722 mu M. alpha-TP activity in capsule treated fabric is determined as 61.73 mu g. Presence of the capsules on fabric and also alpha-TP activity has been found to remain effective even after twenty washes at 40 degrees C.Organik Kimya Sanayi ve Tic. A.S. [00783.STZ.2011-1]; Ministry of Science, Industry and Technology, Republic of TurkeyMinistry of Science, Industry & Technology - Turkey [00783.STZ.2011-1]Authors thankfully acknowledge funding support (00783.STZ.2011-1) by Organik Kimya Sanayi ve Tic. A.S. and, Ministry of Science, Industry and Technology, Republic of Turkey