catena-Poly[[bis[quinazolin-4(3H)-one-κN 1]cadmium(II)]-di-μ-chlorido]

The asymmetric unit of the title compound, [CdCl2(C8H6N2O)2]n, consists of one mol­ecule of the 3H-quinazolin-4-one ligand, one Cd2+ cation, which is located on a twofold axis, and one chlorido ligand in a general position. The latter bridges metal cations, forming a one-dimensional polymer along the b axis. The Cd⋯Cd distance along the chain is 3.7309 (7) Å. The octa­hedral coordination around the metal is completed by two ligands in a trans axial geometry which coordinate through the N atom in 1 position. Moderately strong classical N—H⋯O hydrogen bonds around crystallographic inversion centers cross-link adjacent polymeric chains

Diaqua­dichloridobis[quinazolin-4(1H)-one-κN 3]copper(II)

In the title complex, [CuCl2(C8H6N2O)2(H2O)2], the CuII ion is located on an inversion center and is octahedrally coordinated by two N atoms of the 1H-quinazolin-4-one ligand, two chloride ligands and two aqua ligands. The axial Cu—O distances are significantly longer [2.512 (2) Å], than the Cu—N [2.022 (2) Å] and Cu—Cl [2.3232 (4) Å] distances as a result of Jahn–Teller distortion. Aqua ligands are involved in intra- and inter­molecular hydrogen bonding, and N—H⋯O inter­molecular hydrogen bonds are formed between the organic ligands. In addition, weak π–π inter­actions are observed between the benzene rings of the ligand [centroid–centroid distance = 3.678 (1) Å]

TECHNOLOGY OF USING MEDIA EDUCATION IN DEVELOPING PROFESSIONAL TRAINING OF FUTURE BUILDERS-ENGINEERS

The purpose of this work is to analyze  the results obtained from researchers on media education, technology, media education its situation carried out in institutions Builders-engineers in Uzbekistan and its application in training and the development of professional training and the future implies application in activities

6,7,8,9,10,11-Hexahydro-13H-azocino[2,1-b]quinazolin-13-one

The title compound, C14H16N2O, is a synthetic analogue of quinazolone alkaloids with pyrrilo, pyrido and azopino rings. The quinazolinic part of the mol­ecule is generally planar within 0.037 (3) Å; the eight-membered ring exhibits an inter­mediate conformation between the chair and boat forms as it is typical for cyclo­octene rings. An ethyl­ene group of the azopino ring is disordered over two positions with a refined occupancy ratio of 0.910 (7):0.090 (7). In the crystal, the H atoms of the aromatic rings form weak C—H⋯O and C—H⋯N hydrogen bonds. One C—H⋯O hydrogen bond leads to the formation of a one-dimensional chain. Another C—H⋯O and a C—H⋯N bond link these chains, generating a three-dimensional network

11-(2-Oxopyrrolidin-1-ylmeth­yl)-1,2,3,4,5,6,11,11a-octa­hydro­pyrido[2,1-b]quinazolin-6-one dihydrate

In the crystal structure of the title compound, C17H21N3O2·2H2O, water mol­ecules are mutually O—H⋯O hydrogen bonded and form infinite chains propagating along the b axis. Neighboring chains are linked by the quinazoline mol­ecules by means of O—H⋯O=C hydrogen bonds, forming a two–dimensional network

Modeling of stress-deformed conditions of heavy loaded elements of new equipment of metal injection molding technologies

For the production of Metal Injection Molding (MIM) with the technology of long profiles, a pressing device and a multi-roll mill of a new design are proposed. The analysis of the results of mathematical modeling of the stress-strain state (SSS) of heavily loaded elements of new equipment for powder metallurgy using the finite element method and the deformation model of metal strength is presented. The influence of changes in the content of the binder of metal powders obtained in the screw assembly, as well as the size of the initial powder, on the stress-strain state of the heavily loaded elements of the pressing device and the multi-roll mill, respectively, was determined

Diaqua­dichloridobis[quinazolin-4(1H)-one-κN 3]nickel(II)

In the title complex, [NiCl2(C8H6N2O)2(H2O)2], the NiII ion is located on an inversion center and is six-coordinated by two N atoms of 1H-quinazolin-4-one ligands, two chloride ions and two water mol­ecules. The water mol­ecules are involved in intra- and inter­molecular O—H⋯O and O—H⋯Cl hydrogen bonding. Inter­molecular N—H⋯O and N—H⋯Cl hydrogen bonds are formed between ligands. In addition, weak π–π inter­actions are observed between the benzene rings of the ligands [centroid–centroid distance = 3.580 (3) Å]. The inter­molecular hydrogen bonds and π–π inter­actions lead to the formation of a three-dimensional supra­molecular network

Modeling of stress-deformed conditions of heavy loaded elements of new equipment of metal injection molding technologies

For the production of Metal Injection Molding (MIM) with the technology of long profiles, a pressing device and a multi-roll mill of a new design are proposed. The analysis of the results of mathematical modeling of the stress-strain state (SSS) of heavily loaded elements of new equipment for powder metallurgy using the finite element method and the deformation model of metal strength is presented. The influence of changes in the content of the binder of metal powders obtained in the screw assembly, as well as the size of the initial powder, on the stress-strain state of the heavily loaded elements of the pressing device and the multi-roll mill, respectively, was determined

Methods for Producing High-Temperature Superconductors

This paper presents technologies for obtaining high-temperature superconducting materials

The role of intestinal translocation of E.coli in the development of acute obstructive pyelonephritis in an experiment

Aim: To study the role of E. coli intestinal translocation in the development of acute obstructive pyelonephritis in an experiment. Material and methods: An experimental study was conducted on 60 male rabbits weighing 3000±500 g. The animals were divided into 3 groups of 20 animals each: experimental, control and intermediate control group. The acute obstructive pyelonephritis with the ureter blocking by laparotomy and introduction of the strain into the intestine were simulated in the animals of the experimental group. In the control group, the model was performed anologically as in the experimental group, but without the ureter blocking. In the intermediate control group, laparotomy was performed, the ureter was isolated without blocking and without the introduction of a bacterial strain. 10 animals of each group were removed from the experiment on the 3rd and 5th days, kidney tissue and urine were intake. As a reference marker strain, the laboratory strain E. coli No. 49579 was used, which was obtained from a patient with a urological infection and had resistance to cefepime, ciprofloxacin and tetracycline. Biomaterials were studied by microbiological examination and subspecific typing of strains using the MALDI-TOF MS method, antibiotic sensitivity was determined. Results: E. coli strain was isolated in all animals of the experimental group and in 2 animals of the control group on the 5th day. During subspecific typing by the MALDI-TOF MS method, the isolated strains were identical in ribosomal proteins, and also had the same sensitivity to the said antibiotics. When analyzing the amount of lg CFU E.coli in urine after the experiment between the experimental and control group, we found that, on day 3, there were statistically significant differences between the groups (p=0.005), and on day 5, the amount of lg CFU E.coli was 13 times greater (p=0.004).A comparative analysis of the lg CFU E.coli index in kidney tissue on 3 (p=0.004) and 5 (p=0.003) days revealed statistically significant differences between the experimental group and the control group. Conclusion: The results of identification and subspecific typing of isolated microorganisms confirmed that the strains isolated from the urinary tract were identical to the reference strain introduced into the gastrointestinal tract during the experiment, which confirms the role of translocation of intestinal microorganisms in the development of acute obstructive pyelonephritis