Process for dyeing textiles

The present invention relates to a process for dyeing textiles, in particular for dyeing textiles using enzymes. The present invention also relates to a method for producing leuco indigo and/or leuco forms of indigo derivatives. The present invention further refers to textiles obtainable through said process, to an apparatus comprising a reactor containing enzymes, and to a microbial flavin-containing monooxygenase

Process for dyeing textiles

The present invention relates to a process for dyeing textiles, in particular for dyeing textiles using enzymes. The present invention also relates to a method for producing leuco indigo and/or leuco forms of indigo derivatives. The present invention further refers to textiles obtainable through said process, to an apparatus comprising a reactor containing enzymes, and to a microbial flavin-containing monooxygenase

Evaluation of the impact of warfarin time in therapeutic range on outcomes of patients with atrial fibrillation in Turkey: Perspectives from the observational, prospective WATER Registry

Background: Warfarin is highly efficacious in reducing stroke risk in patients with atrial fibrillation (AF). However, its safety and efficacy in stroke prevention is markedly influenced by its time in therapeutic range (TTR). The quality of anticoagulant therapy varies considerably among countries. Representative data concerning the quality of anticoagulant therapy and its effects on clinical outcomes in Turkey are lacking. Methods: Warfarin in Therapeutic Range (WATER) registry is a prospective, observational study which followed 572 AF patients (mean age 67.3 ± 12 years; females 60%; 71% non-valvular AF) treated with warfarin. Results: At a median of 22-month follow-up, the mean TTR value was 42.3 ± 18% (median: 40%) for the whole population and lower in non-valvular AF su group than valvular AF subgroup (40.3 ± 18 vs. 46.9 ± 19, respectively, p < 0.001). Death, cardiac hospital­ization and minor bleeding rates were higher in the group with TTR value < 40% than the group with > 40% (3.4% vs. 5.9%; 28.6% vs. 35.4%; 36.5% vs. 41.7%, respectively, all of them p < 0.001). A correlation analysis showed a negative correlation between age and TTR value (r = –0.178, p < 0.001). Mean CHA2DS2VASc score was 3.63 ± 1.5 and mean HASBLED score was 2.38 ± 1.01 in the non-valvular AF group. A negative correlation was observed between TTR levels and CHA2DS2VASc score. Conclusions: WATER provides insight into the anticoagulation control status of AF patients in Turkey. The quality of anticoagulation was poor. Strategies should be undertaken by clinicians and patients to improve TTR. New oral anticoagulant agents may be perfect alternatives for non-valvular AF patients

Process for dyeing textiles

The present invention relates to a process for dyeing textiles, in particular for dyeing textiles using enzymes. The present invention also relates to a method for producing leuco indigo and/or leuco forms of indigo derivatives. The present invention further refers to textiles obtainable through said process, to an apparatus comprising a reactor containing enzymes, and to a microbial flavin-containing monooxygenase

Hair arsenic concentrations of residents living in Nevsehir province, Turkey

Arsenic-contaminated drinking water affects millions of people worldwide, causing substantial mortality and morbidity from cancers, and cardiovascular and respiratory diseases. Geological studies have recently shown that arsenic (As) levels in drinking water ranged from 11 μg L−1 to 500 μg L−1 in Nevsehir-province. However, little is known about the level of arsenic exposure in this area. This study as a part of ongoing molecular epidemiology research concerning carcinogenic risk related to arsenic exposure was focused on the determination of total arsenic concentration in hair of residents (n = 101) collected from two Nevşehir villages, to evaluate the extent of arsenic exposure. Arsenic concentrations in drinking water of the two villages were ranged from 52.1 μg L−1 to 256.5 μg L−1. For comparative purposes, hair samples of residents (n = 96) were also collected from that area having low levels of As (<10 μg L−1) in drinking water. The median (min–max) values for total arsenic in hair samples from residents of two contaminated villages and for control subjects were 1.17 (0.35–6.48) ppm and 0.14 (0.03–0.98) ppm, respectively (p < 0.001). Sixty-three out of 101 hair samples (62%) collected in the two villages exceeded 1.00 ppm, indicating the toxic effects. The effect of different factors, i.e. age, gender, smoking habits and residence time on arsenic levels in hair was investigated in detail. Our data indicated that arsenic concentrations of hair samples collected from residents of Nevşehir, with higher levels of arsenic in drinking water appeared to be elevated compared with lower levels, which suggested deleterious exposure to arsenic. This study was funded by The Scientific and Technological Research Council of Turkey (TUBITAK) Project No. 109S419