The effect of systematic misperception of income on the subjective poverty line

Income Distribution;macroeconomics

A simultaneous wage and labour supply model with hours restrictions

Labour Market;Production Function;labour economics

The role of epithelial-to-mesenchymal plasticity in ovarian cancer progression and therapy resistance

Ovarian cancer is the most lethal of all gynecologic malignancies and the eighth leading cause of cancer-related deaths among women worldwide. The main reasons for this poor prognosis are late diagnosis; when the disease is already in an advanced stage, and the frequent development of resistance to current chemotherapeutic regimens. Growing evidence demonstrates that apart from its role in ovarian cancer progression, epithelial-to-mesenchymal transition (EMT) can promote chemotherapy resistance. In this review, we will highlight the contribution of EMT to the distinct steps of ovarian cancer progression. In addition, we will review the different types of ovarian cancer resistance to therapy with particular attention to EMT-mediated mechanisms such as cell fate transitions, enhancement of cancer cell survival, and upregulation of genes related to drug resistance. Preclinical studies of anti-EMT therapies have yielded promising results. However, before anti-EMT therapies can be effectively implemented in clinical trials, more research is needed to elucidate the mechanisms leading to EMT-induced therapy resistance

Test your self-leadership skills. How good are you in leading yourself?

When most people think of leaders, they think of famous people like Martin Luther King, John F. Kennedy, or (when talking about toxic leaders), Adolf Hitler. But why not think about ourselves in term of a leader? Academics and professionals interested in ‘self-leadership’ chose this path. Self-leadership literature can provide important lessons for professionals. Self-leadership has been shown to result in greater career success, more job satisfaction and less stress. Read this blog to test your own self-leadership skills and improve them

Connecting public administration and change management literature

Abstract The main goal of this article is to contribute to change management literature in the public sector. A recent literature review argues that there is a gap in the literature on change management specifically using the public administration perspective. We therefore analyze resistance to change in the public sector using an interdisciplinary approach, combining insights from public administration and change management literature. From public administration, we draw on the policy alienation model, which consists of five dimensions: strategic powerlessness, tactical powerlessness, operational powerlessness, societal meaninglessness and client meaninglessness. These factors could influence resistance to change. We test this using two independent large scale samples. Based on Confirmatory Factor Analysis (CFA) and Structural Equation Modeling (SEM), we show that societal and client meaninglessness proved very influential. Furthermore, perceived autonomy (operational powerlessness) strongly influenced resistance to change, whereas strategic and tactical powerlessness were far less important. Based on the results, we nuance this impact of employee influence and participation and highlight the value of meaningful changes/policies. Implications for scholars and a future research agenda regarding change management in the public sector is shown

Street-level bureaucrats help clients, even in difficult circumstances

This policy brief presents the main findings of the Marie Curie Project “COPING: Policy implementation in stressful times: Analyzing coping strategies of civil servants”. The project combines insights from public administration and psychology to study how street-level bureaucrats (also termed frontline workers, public professionals or public service workers) cope with stress during public service delivery