1,822 research outputs found

    Joint Stability And Proprioception Training To Reduce Chronic Pain For A Female Patient With Hypermobile Ehlers-Danlos Syndrome: A Case Report

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    Ehlers-Danlos Syndrome (EDS) is a heritable connective tissue disorder with many subtypes. Hypermobile EDS (hEDS), the most common subtype, is characterized by generalized joint hypermobility, musculoskeletal impairments, systemic involvement, and a familial history of EDS. Due to the many subtypes of EDS, and general hypermobility, a categorization of all terms was created called the Hypermobility Spectrum Disorder. Patients present with physical, psychological, and central nervous system impairments reducing their quality of life (QoL). The purpose of this case report was to describe the interventions utilized for a 28-year-old female with hEDS and chronic pain with the intention of reducing symptoms and promoting return to work.https://dune.une.edu/pt_studcrposter/1188/thumbnail.jp

    Charting Success and Navigating the Challenges in the PSI world

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    Algebraic conditions on Banach algebras.

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    First paragraph: The basic mathematical structure to be studied in this thesis is that of the complex Banach algebra. We shall impose certain algebraic conditions on this structure, in addition to those it already possesses, and investigate the properties which the resulting structure possesses

    Thermochemistry of Amino Acids and Constrained Diamines

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    The gas-phase proton affinities of several highly basic amino acids and diamines were determined using the extended kinetic method in an ESI-quadrupole ion trap instrument. The non-protein amino acid L-canavanine is structurally related to L-arginine with an oxygen substituted for the terminal methylene group of L-arginine and is highly toxic to humans. The proton affinity of L-arginine, a protein amino acid, was determined to be 1036 kJ mol -1, whereas the proton affinity of L-canavanine was determined to be 1005 kJ mol-1. Thus, substitution of an oxyguanidino group for the guanidine group in L-arginine results in a large decrease in basicity. This decrease in basicity mirrors the solution behavior of these two amino acids in which the oxygen atom substitution causes a 5 pKa unit drop in basicity of L-canavanine relative to L-arginine. In addition, the proton affinities of the NPAAs L-canaline and L-citrulline were determined to be 952 kJ mol-1 and 990 kJ mol-1, respectively. The proton affinity values presented here for the NPAAs L-canavanine, L-canaline, and L-citrulline represent the first measurements for these compounds. Experiments were complemented by high-level hybrid density functional theory calculations. Theory values obtained for proton affinities were consistent with the theoretical findings except for L-arginine, which was higher than the experimentally determined value. This may be due to the small number of reference bases in the high basicity range used to determine the experimental value.;The proton affinities of the highly basic diamines cis-1,5-diaminocyclooctane, tetramethylcadaverine, and hexamethylcadaverine were determined to be 1002 kJ mol-1, 1013 kJ mol-1, and 1031 kJ mol-1, respectively. These values are consistent with the theory that diamines display increased basicity due to the stabilization that intramolecular hydrogen bonding provides

    Assessing the Intensity of Late Holocene Montane Settlement and Subsistence Strategies in the Northern Sierra Nevada, California

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    This thesis investigates the precontact settlement patterns of the Nisenan in the northern Sierra Nevada and compares these patterns to studies of Mono and Miwok settlement patterns in the central and southern Sierra Nevada. I assess the degree to which Nisenan settlement and subsistence strategies in the montane environment of the Sierra Nevada differs from other groups occupying similar environments in the Sierra. I predicted the Nisenan would share a similar settlement and subsistence strategy to the Miwok based on both groups sharing similar population densities and culture histories in broadly similar environments. The Nisenan, however, use a settlement pattern that more closely resembles the Mono in intensity but differs in important ways. The Nisenan primarily occupied lower elevation ecozones and relied on lower intensity logistical mobility in the montane ecozones above snowline. Comparatively the Mono were more residentially mobile above snowline and the Miwok use a much more intensive residentially mobile strategy above and below snowline. This study indicates that population density and occupational time depth alone are not sufficient predictors of montane settlement and subsistence strategies. Factors like climate, environment, sociopolitical structures, territoriality, culture history, and seasonal resource availability likely also influence hunter-gatherer decision making when it comes to settlement and subsistence. The Nisenan appear to be a group that was more oriented toward the valley margin and foothills of the Sierra Nevada than montane environments. Additionally, montane environments within the study area may have been used by the Nisenan and the Washoe of the Tahoe region as backup resource patches during times of scarcity in lower elevation environments. This project contributes to our understanding of human adaptations in montane environments and the factors that contribute to group decision-making when it comes to determining settlement and subsistence strategies

    COVID-19 Deaths Linked to Restrictions Stringency Lag: A G7 and Global Analysis, Implications for Public Policy

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    This study focuses on the results of the G7 countries from the analysis of daily data from 184 countries of the world during the COVID-19 epidemic. After an increase in restrictions, there is an increase in new COVID-19 deaths. To understand the influences on number of deaths by country, the analysis reveals that per capita income is significantly positively correlated with mortality from COVID-19. This suggests that the epidemic first hit rich countries the hardest through the correlation to the human development index. This finding was contrary to what was predicted by the Global Health Security Index on pre-pandemic preparedness. Within affluent countries, deaths and cases were higher among socio-economic challenged populations. This was supported by the number of deaths that are positively influenced by the GINI index that is an indicator of disparity of income and wealth. The research indicates that after an increase in restrictions, there is an increase in new COVID-19 deaths and cases. This along with the finding on the stringency index, correlated with the stringency lag, point to the effectiveness of policies being negatively correlated due to a lag in implementation and partial application. Moreover, the uncertainty or the variability of the stringency index has a negative impact on mortality. The “Power Distance” by was used to understand individual’s reaction to restrictions indicated by the stringency index and the stringency lag, COVID-19 death numbers were also found to be positively influenced by a countries “Power Distance”. These findings are key to the improve policy management of the virus. The Delta plus and Lambda variant’s increased transmissibility and potential vaccine resistance increases the urgency for policy makers to understand and immediately enforce the stringency of regulations in consideration of their countries Power Balance index, and to reduce the stringency lag of their policies to increase the effectiveness in reducing the transmission of COVID-19

    Unlocking the potential of public sector information with Semantic Web technology

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    Governments often hold very rich data and whilst much of this information is published and available for re-use by others, it is often trapped by poor data structures, locked up in legacy data formats or in fragmented databases. One of the great benefits that Semantic Web (SW) technology offers is facilitating the large scale integration and sharing of distributed data sources. At the heart of information policy in the UK, the Office of Public Sector Information (OPSI) is the part of the UK government charged with enabling the greater re-use of public sector information. This paper describes the actions, findings, and lessons learnt from a pilot study, involving several parts of government and the public sector. The aim was to show to government how they can adopt SW technology for the dissemination, sharing and use of its data

    Ride of the Waelcyrges : Combating Notions of Feminine Passivity and Monstrous Deviance in Anglo-Saxon Literature

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    This paper endeavors to trace the Anglo-Saxon literary figure of the waelcyrge through all twelve references to her throughout the Anglo-Saxon corpus, and culminates in an application of the waelcyrge trope to two problematic heroines in Beowulf, Modthryth and Hygd. Given the critical history associated with the waelcyrge, this paper attempts to write against the dominant assumption in Anglo-Saxon scholarship that the waelcyrge is a derivative of the Norse valkyrie. Instead, this paper is predicated on the notion that the waelcyrge represents uniquely Anglo-Saxon values that volley between the cultural shift that occurs in the mid-ninth century through the emergence of the comitatus. Throughout the various analyses of the waelcyrge source material and, also, its application to Beowulf, one sees an emergence of feminine mythological constructs, in which the waelcyrge demonstrates tremendous elasticity. Throughout these texts, we see an amalgamation of the warrior woman motif with supernatural tethering to nature. We also see a symbolic veneration of gynecological and obstetric biological processes, including menstruation, conception, and birth, through the incorporation of warrior and military metaphors. To this end, the waelcyrge emerges as a complex didacticism regarding feminine bodily autonomy, and the various anxieties associated with sexual freedom and repression. This paper concludes with the suggestion that the readings of the Anglo-Saxon woman as relegated to one end of a peaceweaving/monstrous binary need not exist. The waelcyrge demonstrates, throughout her sources, the subjective and elastic fidelity to real-life female experiences. For this reason, the paper concludes with a discussion on Beowulf\u27s problematic heroines. Hygd is frequently interpreted as the ideal-queen, whose peaceweaving passivity ensures the survival of her tribe. Modthryth, conversely, is associated with feminine monstrosity and wanton violence. Examining these women within the context of the waelcyrge illuminates the lack of polarity in these figures, and the way in which both demonstrate political and militaristic cunning that greatly exceeds their male counterparts
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