A Dedicated M-Dwarf Planet Search Using The Hobby-Eberly Telescope

We present first results of our planet search program using the 9.2 meter Hobby-Eberly Telescope (HET) at McDonald Observatory to detect planets around M-type dwarf stars via high-precision radial velocity (RV) measurements. Although more than 100 extrasolar planets have been found around solar-type stars of spectral type F to K, there is only a single M-dwarf (GJ 876, Delfosse et al. 1998; Marcy et al. 1998; Marcy et al. 2001) known to harbor a planetary system. With the current incompleteness of Doppler surveys with respect to M-dwarfs, it is not yet possible to decide whether this is due to a fundamental difference in the formation history and overall frequency of planetary systems in the low-mass regime of the Hertzsprung-Russell diagram, or simply an observational bias. Our HET M-dwarf survey plans to survey 100 M-dwarfs in the next 3 to 4 years with the primary goal to answer this question. Here we present the results from the first year of the survey which show that our routine RV-precision for M-dwarfs is 6 m/s. We found that GJ 864 and GJ 913 are binary systems with yet undetermined periods, while 5 out of 39 M-dwarfs reveal a high RV-scatter and represent candidates for having short-periodic planetary companions. For one of them, GJ 436 (rms = 20.6 m/s), we have already obtained follow-up observations but no periodic signal is present in the RV-data.Comment: 12 pages, 14 figures, accepted for publication in the Astronomical Journa

Control of Raman Lasing in the Nonimpulsive Regime

We explore coherent control of stimulated Raman scattering in the nonimpulsive regime. Optical pulse shaping of the coherent pump field leads to control over the stimulated Raman output. A model of the control mechanism is investigated.Comment: 4 pages, 5 figure

Development and Validation of a State-Based Measure of Emotion Dysregulation: The State Difficulties in Emotion Regulation Scale (S-DERS)

Existing measures of emotion dysregulation typically assess dispositional tendencies and are therefore not well suited for study designs that require repeated assessments over brief intervals. The aim of this study was to develop and validate a state-based multidimensional measure of emotion dysregulation. Psychometric properties of the State Difficulties in Emotion Regulation Scale (S-DERS) were examined in a large representative community sample of young adult women drawn from four sites (N = 484). Exploratory factor analysis suggested a four-factor solution, with results supporting the internal consistency, construct validity, and predictive validity of the total scale and the four subscales: Nonacceptance (i.e., nonacceptance of current emotions), Modulate (i.e., difficulties modulating emotional and behavioral responses in the moment), Awareness (i.e., limited awareness of current emotions), and Clarity (i.e., limited clarity about current emotions). S-DERS scores were significantly associated with trait-based measures of emotion dysregulation, affect intensity/reactivity, experiential avoidance, and mindfulness, as well as measures of substance use problems. Moreover, significant associations were found between the S-DERS and state-based laboratory measures of emotional reactivity, even when controlling for the corresponding original DERS scales. Results provide preliminary support for the reliability and validity of the S-DERS as a state-based measure of emotion regulation difficulties

A preliminary investigation of the relationship between emotion regulation difficulties and posttraumatic stress symptoms.

This study examined the relationship between posttraumatic stress (PTS) symptoms and particular aspects of emotion regulation difficulties among trauma-exposed individuals. Participants were an ethnically diverse sample of 108 undergraduates from an urban university. PTS symptom severity was found to be associated with lack of emotional acceptance, difficulty engaging in goal-directed behavior when upset, impulse-control difficulties, limited access to effective emotion regulation strategies, and lack of emotional clarity. Further, overall difficulties in emotion regulation were associated with PTS symptom severity, controlling for negative affect. Finally, individuals exhibiting PTS symptoms indicative of a PTSD diagnosis reported greater difficulties with emotion regulation than those reporting PTS symptoms at a subthreshold level. The implications of these findings for research and treatment are discussed

Conformity Motives For Alcohol Use Are Associated With Risky Sexual Behavior Among Alcohol-Dependent Patients In Residential Substance Abuse Treatment

Alcohol misuse is associated with a variety of negative outcomes, including risky sexual behavior (RSB). In an attempt to better identify the subset of individuals at greatest risk for these negative outcomes, a growing body of research has begun to examine the role of alcohol use motives in risk for alcohol use-related negative outcomes. Although the majority of research in this area has focused on coping motives, conformity motives may be particularly relevant to outcomes such as RSB. Specifically, conformity motives may operate as a proxy risk factor for RSB, reflecting the tendency to engage in interpersonally-oriented risk behaviors in order to avoid rejection, interpersonal conflict, or social ostracism. Therefore, the current study examined the relation between conformity motives for alcohol use and RSB in a sample of 94 patients in a residential substance abuse treatment center. Results indicated that conformity motives were associated with RSB above and beyond other motives for alcohol use, as well as relevant covariates. Findings support the notion that conformity motives may operate as a proxy risk factor that could assist in identifying individuals at elevated risk for engaging in RSB

Surface abundances of light elements for a large sample of early B-type stars - IV. The magnesium abundance in 52 stars - a test of metallicity

From high-resolution spectra a non-LTE analysis of the MgII 4481.2 A feature is implemented for 52 early and medium local B stars on the main sequence (MS). The influence of the neighbouring line AlIII 4479.9 A is considered. The magnesium abundance is determined; it is found that log e(Mg) = 7.67 +- 0.21 on average. It is shown that uncertainties in the microturbulent parameter Vt are the main source of errors in log e(Mg). When using 36 stars with the most reliable Vt values derived from OII and NII lines, we obtain the mean abundance log e(Mg) = 7.59 +- 0.15. The latter value is precisely confirmed for several hot B stars from an analysis of the MgII 7877 A weak line. The derived abundance log e(Mg) = 7.59 +- 0.15 is in excellent agreement with the solar magnesium abundance log e_sun(Mg) = 7.55 +- 0.02, as well as with the proto-Sun abundance log e_ps(Mg) = 7.62 +- 0.02. Thus, it is confirmed that the Sun and the B-type MS stars in our neighbourhood have the same metallicity.Comment: 9 pages, 6 figures. Has been accepted for publication at MNRA

Muscle p70S6K phosphorylation in response to soy and dairy rich meals in middle aged men with metabolic syndrome: a randomised crossover trial

The mammalian target of rapamycin (mTOR) pathway is the primary regulator of muscle protein synthesis. Metabolic syndrome (MetS) is characterized by central obesity and insulin resistance; little is known about how MetS affects the sensitivity of the mTOR pathway to feeding

MASTR-MS: A web-based collaborative laboratory information management system (LIMS) for metabolomics

Background An increasing number of research laboratories and core analytical facilities around the world are developing high throughput metabolomic analytical and data processing pipelines that are capable of handling hundreds to thousands of individual samples per year, often over multiple projects, collaborations and sample types. At present, there are no Laboratory Information Management Systems (LIMS) that are specifically tailored for metabolomics laboratories that are capable of tracking samples and associated metadata from the beginning to the end of an experiment, including data processing and archiving, and which are also suitable for use in large institutional core facilities or multi-laboratory consortia as well as single laboratory environments. Results Here we present MASTR-MS, a downloadable and installable LIMS solution that can be deployed either within a single laboratory or used to link workflows across a multisite network. It comprises a Node Management System that can be used to link and manage projects across one or multiple collaborating laboratories; a User Management System which defines different user groups and privileges of users; a Quote Management System where client quotes are managed; a Project Management System in which metadata is stored and all aspects of project management, including experimental setup, sample tracking and instrument analysis, are defined, and a Data Management System that allows the automatic capture and storage of raw and processed data from the analytical instruments to the LIMS. Conclusion MASTR-MS is a comprehensive LIMS solution specifically designed for metabolomics. It captures the entire lifecycle of a sample starting from project and experiment design to sample analysis, data capture and storage. It acts as an electronic notebook, facilitating project management within a single laboratory or a multi-node collaborative environment. This software is being developed in close consultation with members of the metabolomics research community

The Majorana Project

Building a \BBz experiment with the ability to probe neutrino mass in the inverted hierarchy region requires the combination of a large detector mass sensitive to \BBz, on the order of 1-tonne, and unprecedented background levels, on the order of or less than 1 count per year in the \BBz signal region. The MAJORANA Collaboration proposes a design based on using high-purity enriched Ge-76 crystals deployed in ultra-low background electroformed Cu cryostats and using modern analysis techniques that should be capable of reaching the required sensitivity while also being scalable to a 1-tonne size. To demonstrate feasibility, the collaboration plans to construct a prototype system, the MAJORANA DEMONSTRATOR, consisting of 30 kg of 86% enriched \Ge-76 detectors and 30 kg of natural or isotope-76-depleted Ge detectors. We plan to deploy and evaluate two different Ge detector technologies, one based on a p-type configuration and the other on n-type.Comment: paper submitted for the 2008 Carolina International Symposium on Neutrino Physic