31 research outputs found
Maternal Anxiety Associated with Newborn Hearing Screening
The purpose of this study was to determine if newborn hearing screening increases maternal anxiety. Mothers whose infants were screened for hearing were asked how worried they were prior to hospital discharge and again six weeks later. They were also asked if they were more concerned about their babyâs hearing than they were about other aspects of the infantâs health and behavior.
Results showed that mothers worried as much or more about many other aspects of their infantsâ health and behavior as about hearing. Mothers whose infants had a false positive screening result were initially more worried about hearing than other aspects of their infantâs health, but this effect disappeared within six weeks. There were no significant differences at Time 1 or Time 2 for maternal anxiety as measured by the State Trait Anxiety Inventory between mothers whose infants had a false positive hearing screen compared to mothers of infants who passed their initial hearing screen.
Participation in newborn hearing screening is not associated with undue worry among mothers of newborns
Nonthermal Hard X-ray Emission and Iron Kalpha Emission from a Superflare on II Pegasi
We report on an X-ray flare detected on the active binary system II~Pegasi
with the Swift telescope. The trigger had a 10-200 keV luminosity of
2.2 erg s-- a superflare, by comparison with energies of
typical stellar flares on active binary systems. The trigger spectrum indicates
a hot thermal plasma with T180 K. X-ray spectral analysis
from 0.8--200 keV with the X-Ray Telescope and BAT in the next two orbits
reveals evidence for a thermal component (T80 K) and Fe K 6.4
keV emission. A tail of emission out to 200 keV can be fit with either an
extremely high temperature thermal plasma (TK) or power-law
emission. Based on analogies with solar flares, we attribute the excess
continuum emission to nonthermal thick-target bremsstrahlung emission from a
population of accelerated electrons. We estimate the radiated energy from
0.01--200 keV to be erg, the total radiated energy over
all wavelengths erg, the energy in nonthermal electrons above 20
keV erg, and conducted energy erg. The
nonthermal interpretation gives a reasonable value for the total energy in
electrons 20 keV when compared to the upper and lower bounds on the thermal
energy content of the flare. This marks the first occasion in which evidence
exists for nonthermal hard X-ray emission from a stellar flare. We investigate
the emission mechanism responsible for producing the 6.4 keV feature, and find
that collisional ionization from nonthermal electrons appears to be more
plausible than the photoionization mechanism usually invoked on the Sun and
pre-main sequence stars.Comment: 41 pages, 7 figures, accepted for publication in the Astrophysical
Journa
The Implementation and Sustainment Facilitation Strategy Improved Implementation Effectiveness and Intervention Effectiveness: Results from a Cluster-Randomized, Type 2 Hybrid Trial
Background: Substance use disorders (SUDs) among people with HIV are both prevalent and problematic. The Substance Abuse Treatment to HIV care project was funded to test the Implementation and Sustainment Facilitation (ISF) strategy as an adjunct to the Addiction Technology Transfer Center (ATTC) strategy for integrating a motivational interviewing-based brief intervention (MIBI) for SUDs within HIV community-based organizations. Methods: Using a cluster-randomized, type 2 hybrid trial design, 39 HIV organizations were randomized to either (1) ATTC (n = 19) or (2) ATTC + ISF (n = 20). Each HIV organization identified two staff members to be prepared to implement the MIBI (N = 78). Subsequently, during the implementation phase, HIV organizations in each condition randomized client participants (N = 824) to one of the two intervention conditions: usual care (UC; n = 415) or UC + MIBI (n = 409). Both staff-level outcomes and client-level outcomes were examined. Results: The ISF strategy had a significant impact on the implementation effectiveness (i.e., the consistency and the quality of implementation; ÎČ = .65, p = .01) but not on time-to-proficiency (ÎČ = â.02) or level-of-sustainment (ÎČ = .09). In addition, the ISF strategy was found to have a significant impact on the intervention effectiveness (the effectiveness of the MIBI), at least in terms of significantly decreasing the odds (odds ratio = 0.11, p = .02) of clients using their primary substance daily during follow-up. Conclusion: The ISF strategy was found to be an effective adjunct to the ATTC strategy in terms of implementation effectiveness and intervention effectiveness. It is recommended that future efforts to integrate the projectâs MIBI for SUD within HIV organizations use the ATTC + ISF strategy. However, given the ISF strategy did not have a significant impact on level-of-sustainment, implementation research testing the extent to which the ATTC + ISF strategy can be significantly enhanced through effective sustainment strategies is warranted.
Substance use among people living with HIV is associated with increased mental health problems, worse medication adherence, and worse HIV viral suppression. Increasing substance use-related services in HIV community-based organizations is an important public health need. The Substance Abuse Treatment to HIV care project tested two strategies for helping HIV organizations implement a brief intervention (BI) designed to motivate clients to decrease their substance use. The project also tested if receiving a BI improved clientsâ outcome. Two staff from each of the 39 participating organizations were taught how to deliver the BI using the Addiction Technology Transfer Center (ATTC) training strategy (online and in-person training, monthly feedback, and coaching). Half of the organizations also received the Implementation and Sustainment Facilitation (ISF) strategy, which included monthly meetings with an ISF coach for the two BI staff and one or more leadership staff from the organization. Organizations that received both the ATTC and ISF strategies delivered more BIs and higher quality BIs than organizations that only received the ATTC strategy. In addition, clients receiving BIs at organizations that received both strategies were more likely to decrease their substance use. However, receiving both strategies did not improve how quickly staff learned to deliver the BI or improve the number of BIs delivered during the projectâs 6-month sustainment phase. Future research focused on implementing BIs within HIV organizations should consider using the ATTC and ISF strategies while also seeking to enhance the strategies to improve sustainment
Drug and alcohol trajectories among adults with schizophrenia: Data from the CATIE study
The primary aim is to describe drug and alcohol trajectories in adults with schizophrenia
Unveiling the nature of INTEGRAL objects through optical spectroscopy. VIII. Identification of 44 newly detected hard X-ray sources
(abridged) Hard X-ray surveys performed by the INTEGRAL satellite have
discovered a conspicuous fraction (up to 30%) of unidentified objects among the
detected sources. Here we continue our identification program by selecting
probable optical candidates using positional cross-correlation with soft X-ray,
radio, and/or optical archives, and performing optical spectroscopy on them. As
a result, we identified or more accurately characterized 44 counterparts of
INTEGRAL sources: 32 active galactic nuclei, with redshift 0.019 < z < 0.6058,
6 cataclysmic variables (CVs), 5 high-mass X-ray binaries (2 of which in the
Small Magellanic Cloud), and 1 low-mass X-ray binary. This was achieved by
using 7 telescopes of various sizes and archival data from two online
spectroscopic surveys. The main physical parameters of these hard X-ray sources
were also determined using the available multiwavelength information. AGNs are
the most abundant population among hard X-ray objects, and our results confirm
this tendency when optical spectroscopy is used as an identification tool. The
deeper sensitivity of recent INTEGRAL surveys enables one to begin detecting
hard X-ray emission above 20 keV from sources such as LINER-type AGNs and
non-magnetic CVs.Comment: 22 pages, 14 figures, 6 tables, accepted for publication on A&A, main
journa
Unveiling the nature of INTEGRAL objects through optical spectroscopy. IX. 22 more identifications, and a glance into the far hard X-ray Universe
(Abridged) Since its launch in October 2002, the INTEGRAL satellite has
revolutionized our knowledge of the hard X-ray sky thanks to its unprecedented
imaging capabilities and source detection positional accuracy above 20 keV.
Nevertheless, many of the newly-detected sources in the INTEGRAL sky surveys
are of unknown nature. The combined use of available information at longer
wavelengths (mainly soft X-rays and radio) and of optical spectroscopy on the
putative counterparts of these new hard X-ray objects allows us to pinpoint
their exact nature. Continuing our long-standing program that has been running
since 2004, and using 6 different telescopes of various sizes, we report the
classification through optical spectroscopy of 22 more unidentified or poorly
studied high-energy sources detected with the IBIS instrument onboard INTEGRAL.
We found that 16 of them are active galactic nuclei (AGNs), while the remaining
6 objects are within our Galaxy. Among the identified extragalactic sources, 14
are Type 1 AGNs; of these, 6 lie at redshift larger than 0.5 and one has z =
3.12, which makes it the second farthest object detected in the INTEGRAL
surveys up to now. The remaining AGNs are of type 2, and one of them is a pair
of interacting Seyfert 2 galaxies. The Galactic objects are identified as two
cataclysmic variables, one high-mass X-ray binary, one symbiotic binary and two
chromospherically active stars. We thus still find that AGNs are the most
abundant population among hard X-ray objects identified through optical
spectroscopy. Moreover, we note that the higher sensitivity of the more recent
INTEGRAL surveys is now enabling the detection of high-redshift AGNs, thus
allowing the exploration of the most distant hard X-ray emitting sources and
possibly of the most extreme blazars.Comment: 18 pages, 9 figures, 8 tables, accepted for publication on Astronomy
& Astrophysics, main journa
Jail-to-community treatment continuum for adults with co-occurring substance use and mental disorders: study protocol for a pilot randomized controlled trial
Abstract Background Adults with co-occurring mental and substance use disorders (CODs) are overrepresented in jails. In-custody barriers to treatment, including a lack of evidence-based treatment options and the often short periods of incarceration, and limited communication between jails and community-based treatment agencies that can hinder immediate enrollment into community care once released have contributed to a cycle of limited treatment engagement, unaddressed criminogenic risks, and (re)arrest among this vulnerable and high-risk population. This paper describes a study that will develop research and communication protocols and adapt two evidence-based treatments, dual-diagnosis motivational interviewing (DDMI) and integrated group therapy (IGT), for delivery to adults with CODs across a jail-to-community treatment continuum. Methods/design Adaptations to DDMI and IGT were guided by the Risk-Need-Responsivity model and the National Institute of Correctionsâ implementation competencies; the development of the implementation framework and communication protocols were guided by the Evidence-Based Interagency Implementation Model for community corrections and the Inter-organizational Relationship model, respectively. Implementation and evaluation of the protocols and adapted interventions will occur via an open trial and a pilot randomized trial. The clinical intervention consists of two in-jail DDMI sessions and 12 in-community IGT sessions. Twelve adults with CODs and four clinicians will participate in the open trial to evaluate the acceptability and feasibility of, and fidelity to, the interventions and research and communication protocols. The pilot controlled trial will be conducted with 60 inmates who will be randomized to either DDMI-IGT or treatment as usual. A baseline assessment will be conducted in jail, and four community-based assessments will be conducted during a 6-month follow-up period. Implementation, clinical, public health, and treatment preference outcomes will be evaluated. Discussion Findings have the potential to improve both jail- and community-based treatment services for adults with CODs as well as inform methods for conducting rigorous pilot implementation and evaluation research in correctional settings and as inmates re-enter the community. Findings will contribute to a growing area of work focused on interrupting the cycle of limited treatment engagement, unaddressed criminogenic risks, and (re)arrest among adults with CODs. Trial registration ClinicalTrials.gov, NCT02214667 . Registered on 10 August 2014
Proceedings of the 3rd Biennial Conference of the Society for Implementation Research Collaboration (SIRC) 2015: advancing efficient methodologies through community partnerships and team science
It is well documented that the majority of adults, children and families in need of evidence-based behavioral health interventionsi do not receive them [1, 2] and that few robust empirically supported methods for implementing evidence-based practices (EBPs) exist. The Society for Implementation Research Collaboration (SIRC) represents a burgeoning effort to advance the innovation and rigor of implementation research and is uniquely focused on bringing together researchers and stakeholders committed to evaluating the implementation of complex evidence-based behavioral health interventions. Through its diverse activities and membership, SIRC aims to foster the promise of implementation research to better serve the behavioral health needs of the population by identifying rigorous, relevant, and efficient strategies that successfully transfer scientific evidence to clinical knowledge for use in real world settings [3]. SIRC began as a National Institute of Mental Health (NIMH)-funded conference series in 2010 (previously titled the âSeattle Implementation Research Conferenceâ; $150,000 USD for 3 conferences in 2011, 2013, and 2015) with the recognition that there were multiple researchers and stakeholdersi working in parallel on innovative implementation science projects in behavioral health, but that formal channels for communicating and collaborating with one another were relatively unavailable. There was a significant need for a forum within which implementation researchers and stakeholders could learn from one another, refine approaches to science and practice, and develop an implementation research agenda using common measures, methods, and research principles to improve both the frequency and quality with which behavioral health treatment implementation is evaluated. SIRCâs membership growth is a testament to this identified need with more than 1000 members from 2011 to the present.ii SIRCâs primary objectives are to: (1) foster communication and collaboration across diverse groups, including implementation researchers, intermediariesi, as well as community stakeholders (SIRC uses the term âEBP championsâ for these groups) â and to do so across multiple career levels (e.g., students, early career faculty, established investigators); and (2) enhance and disseminate rigorous measures and methodologies for implementing EBPs and evaluating EBP implementation efforts. These objectives are well aligned with Glasgow and colleaguesâ [4] five core tenets deemed critical for advancing implementation science: collaboration, efficiency and speed, rigor and relevance, improved capacity, and cumulative knowledge. SIRC advances these objectives and tenets through in-person conferences, which bring together multidisciplinary implementation researchers and those implementing evidence-based behavioral health interventions in the community to share their work and create professional connections and collaborations
Effects of sample size and distributional assumptions on competing models of the factor structure of the PANSS and BPRS
Factor analytic work on the Positive and Negative Syndrome Scale (PANSS) and Brief Psychiatric Rating Scale (BPRS) has yielded varied and conflicting results. The current study explored potential causes of these discrepancies. Prior research has been limited by small sample sizes and an incorrect assumption that the items are normally distributed when in practice responses are highly skewed ordinal variables. Using simulation methodology, we examined the effects of sample size, (in)correctly specifying item distributions, collapsing rarely endorsed response categories, and four factor analytic models. The first is the model of Van Dorn et al., developed using a large integrated data set, specified the item distributions as multinomial, and used cross-validation. The remaining models were developed specifying item distributions as normal: the commonly used pentagonal model of White et al.; the model of Van der Gaag et al. developed using extensive cross-validation methods; and the model of Shafer developed through meta-analysis. Our simulation results indicated that incorrectly assuming normality led to biases in model fit and factor structure, especially for small sample size. Collapsing rarely used response options had negligible effects
The Implementation and Sustainment Facilitation Strategy Improved Implementation Effectiveness and Intervention Effectiveness: Results from a Cluster-Randomized, Type 2 Hybrid Trial
Background: Substance use disorders (SUDs) among people with HIV are both prevalent and problematic. The Substance Abuse Treatment to HIV care project was funded to test the Implementation and Sustainment Facilitation (ISF) strategy as an adjunct to the Addiction Technology Transfer Center (ATTC) strategy for integrating a motivational interviewing-based brief intervention (MIBI) for SUDs within HIV community-based organizations. Methods: Using a cluster-randomized, type 2 hybrid trial design, 39 HIV organizations were randomized to either (1) ATTC (n = 19) or (2) ATTC + ISF (n = 20). Each HIV organization identified two staff members to be prepared to implement the MIBI (N = 78). Subsequently, during the implementation phase, HIV organizations in each condition randomized client participants (N = 824) to one of the two intervention conditions: usual care (UC; n = 415) or UC + MIBI (n = 409). Both staff-level outcomes and client-level outcomes were examined. Results: The ISF strategy had a significant impact on the implementation effectiveness (i.e., the consistency and the quality of implementation; ÎČ = .65, p = .01) but not on time-to-proficiency (ÎČ = â.02) or level-of-sustainment (ÎČ = .09). In addition, the ISF strategy was found to have a significant impact on the intervention effectiveness (the effectiveness of the MIBI), at least in terms of significantly decreasing the odds (odds ratio = 0.11, p = .02) of clients using their primary substance daily during follow-up. Conclusion: The ISF strategy was found to be an effective adjunct to the ATTC strategy in terms of implementation effectiveness and intervention effectiveness. It is recommended that future efforts to integrate the projectâs MIBI for SUD within HIV organizations use the ATTC + ISF strategy. However, given the ISF strategy did not have a significant impact on level-of-sustainment, implementation research testing the extent to which the ATTC + ISF strategy can be significantly enhanced through effective sustainment strategies is warranted.
Substance use among people living with HIV is associated with increased mental health problems, worse medication adherence, and worse HIV viral suppression. Increasing substance use-related services in HIV community-based organizations is an important public health need. The Substance Abuse Treatment to HIV care project tested two strategies for helping HIV organizations implement a brief intervention (BI) designed to motivate clients to decrease their substance use. The project also tested if receiving a BI improved clientsâ outcome. Two staff from each of the 39 participating organizations were taught how to deliver the BI using the Addiction Technology Transfer Center (ATTC) training strategy (online and in-person training, monthly feedback, and coaching). Half of the organizations also received the Implementation and Sustainment Facilitation (ISF) strategy, which included monthly meetings with an ISF coach for the two BI staff and one or more leadership staff from the organization. Organizations that received both the ATTC and ISF strategies delivered more BIs and higher quality BIs than organizations that only received the ATTC strategy. In addition, clients receiving BIs at organizations that received both strategies were more likely to decrease their substance use. However, receiving both strategies did not improve how quickly staff learned to deliver the BI or improve the number of BIs delivered during the projectâs 6-month sustainment phase. Future research focused on implementing BIs within HIV organizations should consider using the ATTC and ISF strategies while also seeking to enhance the strategies to improve sustainment