Hubungan Komunikasi Dalam Keluarga Dengan Perkembangan Psikologis Anak Asia Sekolah (6-12 Tahun) Di Desa Tumaratas Dua Kecamatan Langowan Bara

: Good communication in families is very important in times of psychological development of school-aged children. The purpose of research to determine the relationship of communication in families with school-age children development. Cross sectional method, with the total sampling of as many as 40 of the respondents. The Data processed with SPSS for analysis by the method of chi-square test at 95% significance level (α= 0.05). The research results showed that respondents with a good category for communication within the family as well as the development of appropriate psychological there are a total of 16 respondents (84.2%) and respondents are categorized well for communication within the family but not in accordance with the development of the psychological as much as 3 of the respondents (15.8%). the respondents by category is bad for communication within the family but in accordance with the psychological development of school-aged children as much as 9 respondents (42,9%) and respondents who considered bad for communication within the family but did not match psychological development of as many as 12 respondents (57,1%). Conclusion there is a meaningful relationship communication in families with the psychological development of school-aged children (6-12 years) in the village of Tumaratas west of two district Langowan with value p = 0.007 and value analysis of the Odds Ratio (OR) obtained the value of 7,111

Hubungan Antara Perilaku Cuci Tangan Pakai Sabun Dengan Terjadinya Diare Pada Anak Usia Sekolah Di SD Gmim Dua Kecamatan Tareran

: Diarrhea is an objec abnormal stools with frequency of spending three times or more with a view consistent mushy, liquid, until with or without blood and mucus in the stool. Objective: to analyze the relationship between the behavior of handwashing with soap by the occurrence of diarrhea in children in elementary school elementary district Lansot Tareran GMIM 2. This research is the cross-sectional relationship mencara anatara sabub handwashing behavior with the occurrence of diarrhea in children of primary school. The population of primary school children in elementary GMIM 2 Lansot 1sampai sitting in class 6 were present and willing to be a respondent. Results: The study shows that handwashing with soap as many as 55 children (93.2%), and were not accustomed to 4 children (6.8%). Elementary school children who suffer diarrhea in the last 3bulan total of 11 children (18.6%), while children who do not suffer from diarrhea, 48 children (81.4%). Conclusion: There is a relationship between the behavior of handwashing with soap by the occurrence of diarrhea in children of primary school age in primary GMIM 2 Lansot Tareran District. With p = 0.003, this means the relationship anatara handwashing with soap is very important to prevent diseases including diarrhea

Hubungan Dukungan Keluarga Dengan Tingkat Kecemasan Akibat Hospitalisasi Pada Anak Di Usia PRA Sekolah Di Irina E Blu Rsup Prof Dr.r.d Kandou Manado

: Family is a collection of two or more people, who each other are emotionally attached to eachother, as well as the same residence in an adjacent area. Family support is an attitude, actionand acceptance of the family members. Anxiety is an individual response to a state that is notpleasant and experienced by all living things in everyday life. The purpose of this study to determine the relationship of family support with levels of anxiety due to hospitalization at preschool age children in Irina E Blu Hospital Prof. Dr. RD Kandou Manado. Methods This study is a descriptive analytic cross sectional study. Accidental sampling technique that sampling with a sample of 30 respondents.Results: The statistical test used in this study is the result of Chi Square (X2) is 4,455 with a significant level of p = 0, 035 because of p <0.05 which means that there is a relationship between the level of family support with anxiety due to hospitalization in children aged pre-school BLU Prof Dr Dr.RD Kandou Manado. Conclusion the better support provided by the family can reduce the level of anxiety in children who experienced hospitalization

Gambaran Indeks Maya Pada Rumah Penderita Demam Berdarah Dengue Di Kelurahan Kombos Barat Kecamatan Singkil Tahun 2015

: Dengue hemorrhagic fever (DHF) is a viral disease that can cause death within a very short time (a few days). The main vector of DHF is Aedes aegypti mosquito, whereas the potential vector is Aedes albopictus. In the context of prevention of DHF, environmental data associated with bionomics mosquito vector of DHF, the Maya Index, are needed. DHF is still a public health problem. And for the case that there is in the city of Manado in 2013, in this case in the district of Singkil, acquired as many as 43 cases of dengue hemorrhagic fever. This study aimed to describe the Maya Index at the houses of dengue hemorrhagic fever patients in the village of West Kombos, Singkil districts. Maya Index is based on hygiene risk index (HRI) and breeding risk index (BRI). This was a descriptive study. Samples were houses of patients with DHF in 2015 from January to December. The results showed that there were four patients during the year 2015. Observation of the four houses and calculation of the data indicated that two houses were in low category of Maya Index, one house in medium category of Maya Index, and one house in high category of Maya Index

Density limit in discharges with high internal inductance on JT-60U

High densities exceeding the Greenwald limit by a factor of 1.7 have been obtained in L-mode discharges with high internal inductances of elli as high as 2.8 in JT-60U. The internal inductance is controlled by ramping down the plasma current. In addition to the extension of the operational regime limited by disruptions, confinement performance remains as good as an H89PL factor of 1.6 even above the Greenwald limit. While an earlier high elli study has indicated core confinement improvement due to enhancement of the poloidal field, the additional improvement of the tolerance against the high density turned out to be correlated with high edge temperature. The normalized density when the detachment occurs, characterized by a decrease in the Dα signal at the divertor, is even higher in the case with no disruption than in the case with a disruption. These comparisons have indicated that the improvement in thermal and particle transport does exist in the periphery and in the edge in high elli plasmas, and the shift of the density limit towards higher densities is observed coincidently. Although the high elli discharge studied here lies outside the usual parameter space for steady-state operation of a tokamak, demonstration of a stable discharge with good confinement beyond the Greenwald limit suggests that the magnetic shear at the edge is one key parameter to uncover the physical elements of the operational density limit

Clinical laboratory reference values amongst children aged 4 weeks to 17 months in Kilifi, Kenya: A cross sectional observational study

Reference intervals for clinical laboratory parameters are important for assessing eligibility, toxicity grading and management of adverse events in clinical trials. Nonetheless, haematological and biochemical parameters used for clinical trials in sub-Saharan Africa are typically derived from industrialized countries, or from WHO references that are not region-specific. We set out to establish community reference values for haematological and biochemical parameters amongst children aged 4 weeks to 17 months in Kilifi, Kenya. We conducted a cross sectional study nested within phase II and III trials of RTS, S malaria vaccine candidate. We analysed 10 haematological and 2 biochemical parameters from 1,070 and 423 community children without illness prior to experimental vaccine administration. Statistical analysis followed Clinical and Laboratory Standards Institute EP28-A3c guidelines. 95% reference ranges and their respective 90% confidence intervals were determined using non-parametric methods. Findings were compared with published ranges from Tanzania, Europe and The United States. We determined the reference ranges within the following age partitions: 4 weeks to <6 months, 6 months to less than <12 months, and 12 months to 17 months for the haematological parameters; and 4 weeks to 17 months for the biochemical parameters. There were no gender differences for all haematological and biochemical parameters in all age groups. Hb, MCV and platelets 95% reference ranges in infants largely overlapped with those from United States or Europe, except for the lower limit for Hb, Hct and platelets (lower); and upper limit for platelets (higher) and haematocrit(lower). Community norms for common haematological and biochemical parameters differ from developed countries. This reaffirms the need in clinical trials for locally derived reference values to detect deviation from what is usual in typical children in low and middle income countries

Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in children in Sierra Leone: a randomised, double-blind, controlled trial

Background—Children account for a substantial proportion of cases and deaths from Ebola virus disease. We aimed to assess the safety and immunogenicity of a two-dose heterologous vaccine regimen, comprising the adenovirus type 26 vector-based vaccine encoding the Ebola virus glycoprotein (Ad26.ZEBOV) and the modified vaccinia Ankara vectorbased vaccine, encoding glycoproteins from the Ebola virus, Sudan virus, and Marburg virus, and the nucleoprotein from the Tai Forest virus (MVA-BN-Filo), in a paediatric population in Sierra Leone. Methods—This randomised, double-blind, controlled trial was done at three clinics in Kambia district, Sierra Leone. Healthy children and adolescents aged 1–17 years were enrolled in three age cohorts (12–17 years, 4–11 years, and 1–3 years) and randomly assigned (3:1), via computer-generated block randomisation (block size of eight), to receive an intramuscular injection of either Ad26.ZEBOV (5 × 1010 viral particles; first dose) followed by MVA-BN-Filo (1 × 108 infectious units; second dose) on day 57 (Ebola vaccine group), or a single dose of meningococcal quadrivalent (serogroups A, C, W135, and Y) conjugate vaccine (MenACWY; first dose) followed by placebo (second dose) on day 57 (control group). Study team personnel (except for those with primary responsibility for study vaccine preparation), participants, and their parents or guardians were masked to study vaccine allocation. The primary outcome was safety, measured as the occurrence of solicited local and systemic adverse symptoms during 7 days after each vaccination, unsolicited systemic adverse events during 28 days after each vaccination, abnormal laboratory results during the study period, and serious adverse events or immediate reportable events throughout the study period. The secondary outcome was immunogenicity (humoral immune response), measured as the concentration of Ebola virus glycoprotein-specific binding antibodies at 21 days after the second dose. The primary outcome was assessed in all participants who had received at least one dose of study vaccine and had available reactogenicity data, and immunogenicity was assessed in all participants who had received both vaccinations within the protocol-defined time window, had at least one evaluable post-vaccination sample, and had no major protocol deviations that could have influenced the immune response. This study is registered at ClinicalTrials.gov, NCT02509494. Findings—From April 4, 2017, to July 5, 2018, 576 eligible children or adolescents (192 in each of the three age cohorts) were enrolled and randomly assigned. The most common solicited local adverse event during the 7 days after the first and second dose was injection-site pain in all age groups, with frequencies ranging from 0% (none of 48) of children aged 1–3 years after placebo injection to 21% (30 of 144) of children aged 4–11 years after Ad26.ZEBOV vaccination. The most frequently observed solicited systemic adverse event during the 7 days was headache in the 12–17 years and 4–11 years age cohorts after the first and second dose, and pyrexia in the 1–3 years age cohort after the first and second dose. The most frequent unsolicited adverse event after the first and second dose vaccinations was malaria in all age cohorts, irrespective of the vaccine types. Following vaccination with MenACWY, severe thrombocytopaenia was observed in one participant aged 3 years. No other clinically significant laboratory abnormalities were observed in other study participants, and no serious adverse events related to the Ebola vaccine regimen were reported. There were no treatment-related deaths. Ebola virus glycoprotein-specific binding antibody responses at 21 days after the second dose of the Ebola virus vaccine regimen were observed in 131 (98%) of 134 children aged 12–17 years (9929 ELISA units [EU]/mL [95% CI 8172–12 064]), in 119 (99%) of 120 aged 4–11 years (10 212 EU/mL [8419–12 388]), and in 118 (98%) of 121 aged 1–3 years (22 568 EU/mL [18 426–27 642]). Interpretation—The Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen was well tolerated with no safety concerns in children aged 1–17 years, and induced robust humoral immune responses, suggesting suitability of this regimen for Ebola virus disease prophylaxis in children