Phase diagram at finite temperature and quark density in the strong coupling limit of lattice QCD for color SU(3)

We study the phase diagram of quark matter at finite temperature (T) and finite chemical potential (mu) in the strong coupling limit of lattice QCD for color SU(3). We derive an analytical expression of the effective free energy as a function of T and mu, including baryon effects. The finite temperature effects are evaluated by integrating over the temporal link variable exactly in the Polyakov gauge with anti-periodic boundary condition for fermions. The obtained phase diagram shows the first order phase transition at low temperatures and the second order phase transition at high temperatures separated by the tri-critical point in the chiral limit. Baryon has effects to reduce the effective free energy and to extend the hadron phase to a larger mu direction at low temperatures.Comment: 18 pages, 10 figure

Nonlinear magnetic responses at the phase boundaries around helimagnetic and skyrmion lattice phases in MnSi: Evaluation of robustness of noncollinear spin texture

The phase diagram of a cubic chiral magnet MnSi with multiple Dzyaloshinskii-Moriya (DM) vectors as a function of temperature T and dc magnetic field Hdc was investigated using intensity mapping of the odd-harmonic responses of ac magnetization (M1ω andM3ω), and the responses at phase boundaries were evaluated according to a prescription [J. Phys. Soc. Jpn. 84, 104707 (2015)]. By evaluating M3ω/M1ω appearing at phase boundaries, the robustness of noncollinear spin texture in both the helimagnetic (HM) and the skyrmion lattice (SkL) phases of MnSi was discussed. The robustness of vortices-type solitonic texture SkL in MnSi is smaller than those of both the single DM HM and chiral soliton lattice phases of a monoaxial chiral magnet Cr1/3NbS2, and furthermore the robustness of the multiple DM HM phase in MnSi is smaller than that of its SkL. Through magnetic diagnostics over the wide T -Hdc range, we found a new paramagnetic (PM) region with ac magnetic hysteresis, where spin fluctuations have been observed via electrical magnetochiral effect. The anomalies observed in the previous ultrasonic attenuation measurement correspond to the peak positions of out-of-phase M1ω. The appearance of a new PM region occurs at a characteristic magnetic field, above which indeed the SkL phase appears. It has us suppose that the new PM region could be a phase with spin fluctuation like the skyrmion gas phase

Isothermal Shock Formation in Non-Equatorial Accretion Flows around Kerr Black Holes

We explore isothermal shock formation in non-equatorial, adiabatic accretion flows onto a rotating black hole, with possible application to some active galactic nuclei (AGNs). The isothermal shock jump conditions as well as the regularity condition, previously developed for one-dimensional (1D) flows in the equatorial plane, are extended to two-dimensional (2D), non-equatorial flows, to explore possible geometrical effects. The basic hydrodynamic equations with these conditions are self-consistently solved in the context of general relativity to explore the formation of stable isothermal shocks. We find that strong shocks are formed in various locations above the equatorial plane, especially around a rapidly-rotating black hole with the prograde flows (rather than a Schwarzschild black hole). The retrograde flows are generally found to develop weaker shocks. The energy dissipation across the shock in the hot non-equatorial flows above the cooler accretion disk may offer an attractive illuminating source for the reprocessed features, such as the iron fluorescence lines, which are often observed in some AGNs.Comment: 22 pages with 11 figures, presented at 5th international conference on high energy density laboratory astrophysics in Tucson, Arizona. accepted to Ap

Iron K-alpha Fluorescent Line Profiles from Spiral Accretion Flows in AGNs

We present 6.4 keV iron K-alpha fluorescent line profiles predicted for a relativistic black hole accretion disk in the presence of a spiral motion in Kerr geometry, the work extended from an earlier literature motivated by recent magnetohydrodynamic (MHD) simulations. The velocity field of the spiral motion, superposed on the background Keplerian flow, results in a complicated redshift distribution in the accretion disk. An X-ray source attributed to a localized flaring region on the black hole symmetry axis illuminates the iron in the disk. The emissivity form becomes very steep because of the light bending effect from the primary X-ray source to the disk. The predicted line profile is calculated for various spiral waves, and we found, regardless of the source height, that: (i) a multiple-peak along with a classical double-peak structure generally appears, (ii) such a multiple-peak can be categorized into two types, sharp sub-peaks and periodic spiky peaks, (iii) a tightly-packed spiral wave tends to produce more spiky multiple peaks, whereas (iv) a spiral wave with a larger amplitude seems to generate more sharp sub-peaks, (v) the effect seems to be less significant when the spiral wave is centrally concentrated, (vi) the line shape may show a drastic change (forming a double-peak, triple-peak or multiple-peak feature) as the spiral wave rotates with the disk. Our results emphasize that around a rapidly-rotating black hole an extremely redshifted iron line profile with a noticeable spike-like feature can be realized in the presence of the spiral wave. Future X-ray observations, from {\it Astro-E2} for example, will have sufficient spectral resolution for testing our spiral wave model which exhibits unique spike-like features.Comment: 30 pages, 10 figures, submitted to ApJ, will be presented at 204th Meeting of AAS in Denve

Depletion of the histone chaperone tNASP inhibits proliferation and induces apoptosis in prostate cancer PC-3 cells

<p>Abstract</p> <p>Background</p> <p>NASP (Nuclear Autoantigenic Sperm Protein) is a histone chaperone that is present in all dividing cells. NASP has two splice variants: tNASP and sNASP. Only cancer, germ, transformed, and embryonic cells have a high level of expression of the tNASP splice variant. We examined the consequences of tNASP depletion for prostate cancer PC-3 cells.</p> <p>Methods</p> <p>tNASP was depleted from prostate cancer PC-3 cells, cervical cancer HeLa cells, and prostate epithelial PWR-1E cells using lentivirus expression of tNASP shRNA. Cell cycle changes were studied by proliferation assay with CFSE labeling and double thymidine synchronization. Gene expression profiles were detected using RT²Profiler PCR Array, Western and Northern blotting.</p> <p>Results</p> <p>PC-3 and HeLa cells showed inhibited proliferation, increased levels of cyclin-dependant kinase inhibitor p21 protein and apoptosis, whereas non-tumorigenic PWR-1E cells did not. All three cell types showed decreased levels of HSPA2. Supporting in vitro experiments demonstrated that tNASP, but not sNASP is required for activation of HSPA2.</p> <p>Conclusions</p> <p>Our results demonstrate that PC-3 and HeLa cancer cells require tNASP to maintain high levels of HSPA2 activity and therefore viability, while PWR-1E cells are unaffected by tNASP depletion. These different cellular responses most likely arise from changes in the interaction between tNASP and HSPA2 and disturbed tNASP chaperoning of linker histones. This study has demonstrated that tNASP is critical for the survival of prostate cancer cells and suggests that targeting tNASP expression can lead to a new approach for prostate cancer treatment.</p

Thermal X-Ray Pulses Resulting From Pulsar Glitches

The non-spherically symmetric transport equations and exact thermal evolution model are used to calculate the transient thermal response to pulsars. The three possible ways of energy release originated from glitches, namely the `shell', `ring' and `spot' cases are compared. The X-ray light curves resulting from the thermal response to the glitches are calculated. Only the `spot' case and the `ring' case are considered because the `shell' case does not produce significant modulative X-rays. The magnetic field ($\vec B$) effect, the relativistic light bending effect and the rotational effect on the photons being emitted in a finite region are considered. Various sets of parameters result in different evolution patterns of light curves. We find that this modulated thermal X-ray radiation resulting from glitches may provide some useful constraints on glitch models.Comment: 48 pages, 20 figures, submitted to Ap