Generating a Schr\"odinger-cat-like state via a coherent superposition of photonic operations

We propose an optical scheme to generate a superposition of coherent states with enhanced size adopting an interferometric setting at the single-photon level currently available in the laboratory. Our scheme employs a nondegenerate optical parametric amplifier together with two beam splitters so that the detection of single photons at the output conditionally implements the desired superposition of second-order photonic operations. We analyze our proposed scheme by considering realistic on-off photodetectors with nonideal efficiency in heralding the success of conditional events. A high-quality performance of our scheme is demonstrated in view of various criteria such as quantum fidelity, mean output energy, and measure of quantum interference

Quantum receiver beyond the standard quantum limit of coherent optical communication

The most efficient modern optical communication is known as coherent communication and its standard quantum limit (SQL) is almost reachable with current technology. Though it has been predicted for a long time that this SQL could be overcome via quantum mechanically optimized receivers, such a performance has not been experimentally realized so far. Here we demonstrate the first unconditional evidence surpassing the SQL of coherent optical communication. We implement a quantum receiver with a simple linear optics configuration and achieve more than 90% of the total detection efficiency of the system. Such an efficient quantum receiver will provide a new way of extending the distance of amplification-free channels, as well as of realizing quantum information protocols based on coherent states and the loophole-free test of quantum mechanics.Comment: 5 pages, 3 figure

Experiences regarding maternal age-specific risks and prenatal testing of women of advanced maternal age in Japan.

The number of pregnant women of advanced maternal age has increased worldwide. Women in this group have an increased chance of fetal abnormality. To explore Japanese women's experiences regarding maternal age-specific risks and prenatal testing, we conducted a descriptive qualitative study. Semi-structured interviews were conducted with 16 women aged 35 years or over who had given birth within the previous three months to a healthy, term infant. Thematic analysis of transcribed interview data was performed and three major themes were identified: inadequate understanding of genetic risks; insufficiently informed choice regarding prenatal testing; and need for more information from health professionals. Some participants were not aware of maternal age-specific risks to the fetus. Many took their cues from health professionals and did not raise the topic themselves, but would have considered prenatal testing if made aware of the risks. Nurses, midwives and other health professionals need to adequately inform pregnant women about the genetic risks to the fetus and offer testing at an appropriate stage early in the pregnancy

Contribution of L-type Ca2+ channels to early afterdepolarizations induced by I-Kr and I-Ks channel suppression in guinea pig ventricular myocytes

ArticleJOURNAL OF MEMBRANE BIOLOGY. 222(3): 151-166(2008)journal articl

Total Angular Momentum Conservation During Tunnelling through Semiconductor Barriers

We have investigated the electrical transport through strained p-Si/Si_{1-x}Ge_x double-barrier resonant tunnelling diodes. The confinement shift for diodes with different well width, the shift due to a central potential spike in a well, and magnetotunnelling spectroscopy demonstrate that the first two resonances are due to tunnelling through heavy hole levels, whereas there is no sign of tunnelling through the first light hole state. This demonstrates for the first time the conservation of the total angular momentum in valence band resonant tunnelling. It is also shown that conduction through light hole states is possible in many structures due to tunnelling of carriers from bulk emitter states.Comment: 4 pages, 4 figure

Einstein-Podolsky-Rosen-like correlation on a coherent-state basis and inseparability of two-mode Gaussian states

The strange property of the Einstein-Podolsky-Rosen (EPR) correlation between two remote physical systems is a primitive object on the study of quantum entanglement. In order to understand the entanglement in canonical continuous-variable systems, a pair of the EPR-like uncertainties is an essential tool. Here, we consider a normalized pair of the EPR-like uncertainties and introduce a state-overlap to a classically correlated mixture of coherent states. The separable condition associated with this state-overlap determines the strength of the EPR-like correlation on a coherent-state basis in order that the state is entangled. We show that the coherent-state-based condition is capable of detecting the class of two-mode Gaussian entangled states. We also present an experimental measurement scheme for estimation of the state-overlap by a heterodyne measurement and a photon detection with a feedforward operation.Comment: 9 pages, 5 figures. A part of the materials in Sec. VI B of previous versions was moved into another paper: Journal of Atomic, Molecular, and Optical Physics, 2012, 854693 (2012). http://www.hindawi.com/journals/jamop/2012/854693

Administration route-dependent vaccine efficiency of murine dendritic cells pulsed with antigens

 Dendritic cells (DCs) loaded with tumour antigens have been successfully used to induce protective tumour immunity in murine models and human trials. However, it is still unclear which DC administration route elicits a superior therapeutic effect. Herein, we investigated the vaccine efficiency of DC2.4 cells, a murine dendritic cell line, pulsed with ovalbumin (OVA) in the murine E.G7-OVA tumour model after immunization via various routes. After a single vaccination using 1 × 106OVA-pulsed DC2.4 cells, tumour was completely rejected in the intradermally (i.d.; three of four mice), subcutaneously (s.c.; three of four mice), and intraperitoneally (i.p.; one of four mice) immunized groups. Double vaccinations enhanced the anti-tumour effect in all groups except the intravenous (i.v.) group, which failed to achieve complete rejection. The anti-tumour efficacy of each immunization route was correlated with the OVA-specific cytotoxic T lymphocyte (CTL) activity evaluated on day 7 post-vaccination. Furthermore, the accumulation of DC2.4 cells in the regional lymph nodes was detected only in the i.d.-and s.c.-injected groups. These results demonstrate that the administration route of antigen-loaded DCs affects the migration of DCs to lymphoid tissues and the magnitude of antigen-specific CTL response. Furthermore, the immunization route affects vaccine efficiency. © 2001 Cancer Research Campaign http://www.bjcancer.co

Empirical comparison of high gradient achievement for different metals in DC and pulsed mode

For the SwissFEL project, an advanced high gradient low emittance gun is under development. Reliable operation with an electric field, preferably above 125 MV/m at a 4 mm gap, in the presence of an UV laser beam, has to be achieved in a diode configuration in order to minimize the emittance dilution due to space charge effects. In the first phase, a DC breakdown test stand was used to test different metals with different preparation methods at voltages up to 100 kV. In addition high gradient stability tests were also carried out over several days in order to prove reliable spark-free operation with a minimum dark current. In the second phase, electrodes with selected materials were installed in the 250 ns FWHM, 500 kV electron gun and tested for high gradient breakdown and for quantum efficiency using an ultra-violet laser.Comment: 25 pages, 13 figures, 5 tables. Follow up from FEL 2008 conference (Geyongju Korea 2008) New Title in JVST A (2010) : Vacuum breakdown limit and quantum efficiency obtained for various technical metals using DC and pulsed voltage source

Mapping coherence in measurement via full quantum tomography of a hybrid optical detector

Quantum states and measurements exhibit wave-like --- continuous, or particle-like --- discrete, character. Hybrid discrete-continuous photonic systems are key to investigating fundamental quantum phenomena, generating superpositions of macroscopic states, and form essential resources for quantum-enhanced applications, e.g. entanglement distillation and quantum computation, as well as highly efficient optical telecommunications. Realizing the full potential of these hybrid systems requires quantum-optical measurements sensitive to complementary observables such as field quadrature amplitude and photon number. However, a thorough understanding of the practical performance of an optical detector interpolating between these two regions is absent. Here, we report the implementation of full quantum detector tomography, enabling the characterization of the simultaneous wave and photon-number sensitivities of quantum-optical detectors. This yields the largest parametrization to-date in quantum tomography experiments, requiring the development of novel theoretical tools. Our results reveal the role of coherence in quantum measurements and demonstrate the tunability of hybrid quantum-optical detectors.Comment: 7 pages, 3 figure