Experimental Study on Carbonation Resistance and Water Absorbing Property of Concrete Crack with repair

Existing RC Buildings have some cracks and the repairing service might last the buildings for long life. The durability of the RC component is evaluated by several ways as like as carbonation resistance test, permeability test, water penetration test, and so on. Therefore, it need to be measured how much advantage the concrete crack with repair have for the durability. The aim of this paper is to study on advantage of repairing a crack of concrete to the carbonation resistance and the waterabsorbing property by the experimental way. The specimens were prepared in the following point. The finishing (direct finishing and mortal tile finishing), crack width (0, 0.05, 0.5, and 2mm), and choice repairing or not. All concrete specimens were formed 10 x 10 x 20cm and those W/C were 0.55. Then, the specimens were tested by the accelerated carbonation. After 4, 8 and 26weeks accelerated carbonation, the carbonation depth and the carbonation shape of the concretes were measured by 1% phenolphthalein reaction. Also, the amount of absorbed water from the bottom were measured at 1, 3, 6, 24, 48, 72 and 168h. From the results, the carbonation went rapidly located in 2cm around the crack in the case of the no-repair specimens, regardless of any finishing. But in the case of the specimens repaired, it went evenly from the exposure side. And water absorbing test results show a trend that water amount of the concrete with a crack more increase than one of the no-crack concrete

Potensi Keanekaragaman Satwaliar Untuk Pengembangan Ekowisata Di Laboratorium Lapangan Konservasi Sumberdaya Hutan Dan Ekowisata Hutan Pendidikan Unhas

This study aims to determine the potential of wildlife diversity that can be developed as an ecotourism attraction in the Field Laboratory of Forest Resources Conservation and Ecotourism, Unhas Educational Forest. The data was collected by survey method using the line transect method and concentration point count method. Data were analyzed to determine the ecological indices, ie; Richness Indices, Evenness Indices, and Diversity Indices. The results showed that Field Laboratory of Forest Resources Conservation and Ecotourism, have the wild life of mammals, birds, insects, reptiles and frogs that have the potential to be used in the development of ecotourism. The wildlife to be developed as an ecotourism attraction, are the Sulawesi Black Monkey, Tarsier, Couscous, Sulawesi Civets, Deer and Wild Boar, as well as a variety of birds, reptiles and frogs

Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy

This is an electronic version of an article published in Amyloid 2010, Vol. 17, No. 1 : Pages 32-35. Amyloid is available online at: http://informahealthcare.com/doi/pdf/10.3109/13506121003619369We report here two patients with amyloidogenic transthyretin (ATTR) Val30Met familial amyloid polyneuropathy (FAP) who developed numbness in both hands and were diagnosed as having bilateral carpal tunnel syndrome (CTS). In both patients systemic TTR amyloidosis consisting of polyneuropathy affecting both upper and lower limbs and/or autonomic dysfunction gradually appeared after surgery for CTS. Although CTS associated with TTR amyloidosis has been known as an initial symptom in some patients with ATTR non-Val30Met FAP and those with senile systemic amyloidosis, this is the first report of ATTR Val30Met FAP patients starting with upper limb neuropathy including CTS-like symptoms. It is also notable that both patients had no genealogical relationship with two Japanese endemic foci of this disease.ArticleAMYLOID. 17(1):32-35 (2010)journal articl

Study on Technical Standards of Reinforced Concrete Structures with Long Service Life when Using Blended Cement and Finishing Materials

It is very important to improve and secure durability of reinforced concrete (RC) building and housing, in order to extend the service life of it. In this study, these were studied experimentally that the contribution ratio of blended cement to the carbonation resistance of concrete when a part of OPC replaced to FA or BFS much more were used for concrete, and the effect of carbonation suppression required for an effective finishing materials when these were applied for concrete surface. As a result, we were able to obtain the knowledge that the contribution ratio to the carbonation resistance of concrete using blended cement with different mixture replacement ratio, and the effect of carbonation suppression required for 4 types of finishing materials and its specifications, from the viewpoint of securing durability and extending the service life of RC structures. Therefore, these were considered to be able to sufficiently contribute to the review of the evaluation method or technical standards concerning about the durability of RC structures prescribed in "Housing Quality Assurance Act" in Japan

Inter-individual Variations in Circadian Misalignment-induced Nafld Pathophysiology in Mice

Pathological consequences of circadian misalignment, such as shift work, show considerable individual differences, but the lack of mechanistic understanding hinders precision prevention to prevent and mitigate disease symptoms. Here, we employed an integrative approach involving physiological, transcriptional, and histological phenotypes to examine inter-individual differences in pre-symptomatic pathological progression, preceding irreversible disease onset, in wild-type mice exposed to chronic jet-lag (CJL). We observed that CJL markedly increased the prevalence of hepatic steatosis with pronounced inter-individual differences. Stratification of individual mice based on CJL-induced hepatic transcriptomic signature, validated by histopathological analysis, pinpoints dysregulation of lipid metabolism. Moreover, the period and power of intrinsic behavioral rhythms were found to significantly correlate with CJL-induced gene signatures. Together, our results suggest circadian rhythm robustness of the animals contributes to inter-individual variations in pathogenesis of circadian misalignment-induced diseases and raise the possibility that these physiological indicators may be available for predictive hallmarks of circadian rhythm disorders

A proposed core curriculum for dental English education in Japan

Background: Globalization of the professions has become a necessity among schools and universities across the world. It has affected the medical and dental professions in terms of curriculum design and student and patient needs. In Japan, where medicine and dentistry are taught mainly in the Japanese language, profession-based courses in English, known as Medical English and Dental English, have been integrated into the existing curriculum among its 83 medical and 29 dental schools. Unfortunately, there is neither a core curriculum nor a model syllabus for these courses. Methods: This report is based on a survey, two discussion forums, a workshop, and finally, the drafting of a proposed core curriculum for dental English approved by consensus of the participants from each university. Results: The core curriculum covers the theoretical aspects, including dental English terms and oral pathologies; and practical aspects, including blended learning and dentist-patient communication. It is divided into modules and is recommended to be offered for at least two semesters. Conclusions: The core curriculum is expected to guide curriculum developers in schools where dental English courses are yet to be offered or are still in their early development. It may also serve as a model curriculum to medical and dental schools in countries in Asia, Europe, Africa, and Central and South America, where English is not the medium of instruction

Prognostic value of plasminogen activator inhibitor-1 in biomarker exploration using multiplex immunoassay in patients with metastatic renal cell carcinoma treated with axitinib

Background and AimsVascular endothelial growth factor-directed therapies play a significant role in patients with metastatic renal cell carcinoma (mRCC). Biomarkers for predicting treatment efficacy and resistance are required to develop personalized medicine. We evaluated multiple serum cytokine levels in patients with mRCC treated with axitinib to explore predictive biomarkers. MethodsFrom September 2012 to October 2015, serum samples were collected from 44 patients with mRCC before treatment and 4weeks after axitinib initiation. Bio-Plex Pro Human Cancer Biomarker Panels 1 and 2 were used to measure levels of 34 serum biomarkers related to angiogenesis and cell proliferation. ResultsPatients with partial response or stable disease had significantly decreased serum plasminogen activator inhibitor-1 (PAI-1) level from pre-treatment to 4weeks after axitinib initiation compared with those with progressive disease (P = .022). The median progression-free survival (PFS) and median overall survival (OS) in patients with increased serum PAI-1 level from pre-treatment to 4weeks after axitinib initiation were significantly shorter than those with decreased serum PAI-1 level (P = .027 and P = .026, respectively). Increased serum PAI-1 level from pre-treatment to 4weeks after axitinib initiation was an independent prognostic marker for shorter PFS and OS in multivariate analyses (P = .015 and P = .032, respectively). The immunohistochemical staining intensity of PAI-1 in tumor specimens was significantly associated with Fuhrman grade and presence of distant metastasis (P = .026 and P = .010, respectively). ConclusionsThe initial change in serum PAI-1 level in the early stage of axitinib treatment could be a useful prognostic biomarker in patients with mRCC