31 research outputs found

    Analgesic effects of alcohol: A systematic review and meta-analysis of controlled experimental studies in healthy participants

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    Despite the long-standing belief in the analgesic properties of alcohol, experimental studies have produced mixed results. This meta-analysis aimed to clarify whether alcohol produces a decrease in experimentally-induced pain and to determine the magnitude of any such effect. PubMed, PsycINFO and Embase databases were searched from inception until 21/4/2016 for controlled studies examining the effect of quantified dosages of alcohol on pain response to noxious stimulation. Eighteen studies involving 404 participants were identified providing alcohol vs. no-alcohol comparisons for 13 tests of pain threshold (N=212) and 9 tests of pain intensity ratings (N=192). Random effects meta- analysis of standardized mean differences (SMD) provided robust support for analgesic effects of alcohol. A mean blood alcohol content (BAC) of approximately 0.08% (3-4 standard drinks) produced a small elevation of pain threshold (SMD=0.35[0.17, 0.54], p=.002), and a moderate-large reduction in pain intensity ratings, (SMD=0.64[0.37, 0.91], p<.0001), or equivalently, a mean reduction of 1.25 points on a 0-10 point pain rating scale. Furthermore, increasing BAC resulted in increasing analgesia, with each .02% BAC increment producing an increase of SMD=.11 for pain threshold and SMD=.20 for reduced pain intensity. Some evidence of publication bias emerged, but statistical correction methods suggested minimal impact on effect size. Taken together, findings suggest that alcohol is an effective analgesic that delivers clinically- relevant reductions in ratings of pain intensity, which could explain alcohol misuse in those with persistent pain despite its potential consequences for long- term health. Further research is needed to corroborate these findings for clinical pain states

    Executive function predicts theory of mind but not social verbal communication in school-aged children with autism spectrum disorder

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    Background: The association between Executive Function (EF) and Theory of Mind (ToM) in Autism spectrum disorder (ASD) has been mainly investigated using false belief tasks, whilst less is known about the EF effect on other ToM facets. Furthermore, the role EF plays in social communication in ASD is mainly assessed using parent-report EF ratings rather than direct assessment. Aims: The aim of this study was to shed more light on the effect of performance-based EF measures on ToM and social communication in middle childhood in ASD relative to neurotypical controls. Methods and Procedures: Cross-sectional data were collected from 64 matched, school-aged children with and without ASD (8-12 years old), tested on measures of EF (inhibition, working memory, cognitive flexibility), ToM mental state/emotion recognition and social verbal communication. Outcomes and Results: Significant group differences were observed only in selective EF skills (inhibition & cognitive flexibility) and social verbal communication. EF working memory contributed to the explained variance of ToM but not social verbal communication in middle childhood. Conclusions and Implications: These findings suggest that EF and ToM are still associated in middle childhood and EF may be a crucial predictor of ToM across childhood in ASD. Implications are discussed regarding the social-cognitive impairment relationship in ASD

    Cool and hot executive functions at 5-years-old as predictors of physical and relational aggression between 5- and 6-years-old

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    To study the role of executive function (EF) in the early development of aggression, the role of cool and hot EF skills at 5 years-old in the development of physical and relational aggression between 5 and 6 years-old was explored. Typically-developing children (N = 80) completed tasks assessing their cool (inhibition, working memory, planning) and hot EF (affective decision making, delay of gratification) skills at 5-years-old. Longitudinal data were collected from teachers that rated children’s aggression when they were 5-, 5.5- and 6-years-old. Inhibitory control at 5-years-old predicted changes in physical and relational aggression between 5- and 6-years old. Early cool EF, but not hot EF, may therefore be associated with aggression and inhibitory control specifically with changes in aggression during early childhood

    Hot and cool executive function in children and adolescents with autism spectrum disorder: Cross-sectional developmental trajectories

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    The development of executive function (EF) in autism spectrum disorder (ASD) has only been investigated using “cool”-cognitive- EF tasks. Little is known about the development of “hot”-affective- EF and whether it follows a similar developmental pathway. This study employed a cross-sectional developmental trajectories approach to examine the developmental changes in cool (working memory, inhibition, planning) and hot EF (delay discounting, affective decision making) of ASD participants (n=79) and controls (n=91) relative to age and IQ, shedding more light on the hot-cool EF organisation. The developmental trajectories of some aspects of cool EF (working memory, planning) differed significantly as a function of age in ASD participants relative to controls. For both hot EFs no significant age-related changes were found in either group. These findings extend our understanding regarding the maturation of EF from childhood through adolescence in ASD

    Bullying and Victimization in Adolescence: Relations with Parental Style and School Climate

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    Σκοπός της έρευνας ήταν να διερευνηθούν οι αντιλήψεις - εμπειρίες εφήβων μαθητών/τριών ως προς τη σύνδεση των γονεϊκών τύπων συμπεριφοράς και του σχολικού κλίματος με την πιθανή εμπλοκή τους σε περιστατικά εκφοβισμού / θυματοποίησης. Πραγματοποιήθηκε ποσοτική έρευνα με δείγμα 198 μαθητών, της Α΄, Β΄ και Γ΄ τάξης λυκείου. Οι συμμετέχοντες μαθητές/τριες απάντησαν σε τρεις κλίμακες μέτρησης, με τις  οποίες αξιολογήθηκαν τα εξής: α) θυματοποίηση – εκφοβισμός, β) γονεϊκοί τύποι συμπεριφοράς και γ) σχολικό κλίμα. Από τη στατιστική ανάλυση των δεδομένων, όσον αφορά τους γονεϊκούς τύπους συμπεριφοράς, διαπιστώνεται σημαντική συσχέτιση του «τυραννικού γονέα» με την εμπλοκή των μαθητών στο φαινόμενο εκφοβισμού / θυματοποίησης και του «ανεκτικού γονέα» μόνο με την εκδήλωση του σχολικού εκφοβισμού. Όσον αφορά το σχολικό κλίμα παρατηρείται σημαντική σχέση με την εκδήλωση του φαινομένου για τη διάσταση της «εμπλοκής». Τέλος, διαπιστώνεται ότι συνολικά το αρνητικό σχολικό κλίμα αποτελεί ισχυρότερο προβλεπτικό παράγοντα της εμπλοκής των μαθητών/τριών σε περιστατικά εκφοβισμού / θυματοποίησης συγκριτικά με τους γονεϊκούς τύπους συμπεριφοράς. Τα αποτελέσματα σχολιάζονται υπό το πρίσμα των σύγχρονων ερευνητικών ευρημάτων και προτείνονται κατευθυντήριες γραμμές για την αξιοποίησή τους σε προγράμματα παρέμβασης για την αντιμετώπιση και πρόληψη του σχολικού εκφοβισμού.The aim of this study was to explore the associations between self-reported bullying, victimization, perceived parental styles and school climate among adolescents. A sample of 198 Greek high-school pupils completed a modified version of the Revised Olweus Bully / Victim Questionnaire, the Parenting Practices Questionnaire and the Maryland’s Safe and Supportive Schools Climate Survey. With regards to perceived parenting practices, results showed that bullying was positively associated with both authoritarianism and permissive parenting styles, whilst victimization only correlated with authoriatirianism. As far as the school climate was concerned, there was a significant relation between poor school engagement and bullying/victimization. Finally, it was found that overall negative school climate was a stronger predictor of student involvement in bullying/victimization compared to parental practices. The results of this study confirm previous findings and are discussed in terms of their implications for interventions against school bullying.
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