4,913 research outputs found
EM Scattering by a Conducting Sphere Coated with a Uniaxial Layer under Arbitrary Illumination Angle in a Fixed Laboratory Frame
Under a fixed laboratory frame, the electromagnetic theory of the scattering of a plane wave of arbitrary polarizations incidence from arbitrary angles by a uniaxial anisotropic medium was obtained for the first time, and could be solved analytically from an eigensystem determined by a uniaxial anisotropic medium. By applying the boundary conditions at respective interfaces of the coated spherical structure, the unknown expansion coefficients can be obtained from the incident field and the electromagnetic fields in the anisotropic medium, and from the scattered field. Not only did the numerical results demonstrate the validity of our proposed theory but this paper shall also provide discussions in relation to some general cases (under arbitrary incident angles) of bistatic radar cross section
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Papillary Thyroid Carcinoma Variants are Characterized by Co-dysregulation of Immune and Cancer Associated Genes.
Papillary thyroid carcinoma (PTC) variants exhibit different prognosis, but critical characteristics of PTC variants that contribute to differences in pathogenesis are not well-known. This study aims to characterize dysregulated immune-associated and cancer-associated genes in three PTC subtypes to explore how the interplay between cancer and immune processes causes differential prognosis. RNA-sequencing data from The Cancer Genome Atlas (TCGA) were used to identify dysregulated genes in each variant. The dysregulation profiles of the subtypes were compared using functional pathways clustering and correlations to relevant clinical variables, genomic alterations, and microRNA regulation. We discovered that the dysregulation profiles of classical PTC (CPTC) and the tall cell variant (TCPTC) are similar and are distinct from that of the follicular variant (FVPTC). However, unique cancer or immune-associated genes are associated with clinical variables for each subtype. Cancer-related genes MUC1, FN1, and S100-family members were the most clinically relevant in CPTC, while APLN and IL16, both immune-related, were clinically relevant in FVPTC. RAET-family members, also immune-related, were clinically relevant in TCPTC. Collectively, our data suggest that dysregulation of both cancer and immune associated genes defines the gene expression landscapes of PTC variants, but different cancer or immune related genes may drive the phenotype of each variant
Effects of Two-Phase Treatment with the Herbst and Preadjusted Edgewise Appliances on the Upper Airway Dimensions
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Towards the Application of Classification Techniques to Test and Identify Faults in Multimedia Systems
The advances in computer and graphic technologies have led to the popular use of multimedia for information exchange. However, multimedia systems are difficult to test. A major reason is that these systems generally exhibit fuzziness in their temporal behaviors. The fuzziness may be caused by the existence of non-deterministic factors in their runtime environments, such as system load and network traffic. It complicates the analysis of test results. The problem is aggravated when a test involves the synchronization of different multimedia streams as well as variations in system loading.\ud
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In this paper, we conduct an empirical study on the testing and fault-identification of multimedia systems by treating the issue as a classification problem. Typical classification techniques, including Bayesian networks, k-nearest neighbor, and neural networks, are experimented with the use of X-Smiles, an open sourced multimedia authoring tool supporting the Synchronized Multimedia Integration Language (SMIL). From these experiments, we make a few interesting observations and give plausible explanations based on the geometrical properties of the test results
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The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma.
Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades. This study aims to identify the most clinically relevant long non-coding RNAs (lncRNAs) to serve as potential biomarkers and treatment targets for muscle invasive bladder cancer (MIBC). Using RNA-sequencing data from 406 patients in The Cancer Genome Atlas (TCGA) database, we identified differentially expressed lncRNAs in MIBC vs. normal tissues. We then associated lncRNA expression with patient survival, clinical variables, oncogenic signatures, cancer- and immune-associated pathways, and genomic alterations. We identified a panel of 20 key lncRNAs that were most implicated in MIBC prognosis after differential expression analysis and prognostic correlations. Almost all lncRNAs we identified are correlated significantly with oncogenic processes. In conclusion, we discovered previously undescribed lncRNAs strongly implicated in the MIBC disease course that may be leveraged for diagnostic and treatment purposes in the future. Functional analysis of these lncRNAs may also reveal distinct mechanisms of bladder cancer carcinogenesis
Scale-free user-network approach to telephone network traffic analysis
PACS number(s): 89.75.Hc, 89.75.Da, 89.75.FbAuthor name used in this publication: Chi K. TseAuthor name used in this publication: Francis C. M. Lau2005-2006 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe
MRI-conditional catheter sensor for contact force and temperature monitoring during cardiac electrophysiological procedures
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How Many Muscles? Optimal Muscles Set Search for Optimizing Myocontrol Performance
In myo-control, for computational and setup constraints, the measurement of a high number of muscles is not always possible: the choice of the muscle set to use in a myo-control strategy depends on the desired application scope and a search for a reduced muscle set, tailored to the application, has never been performed. The identification of such set would involve finding the minimum set of muscles whose difference in terms of intention detection performance is not statistically significant when compared to the original set. Also, given the intrinsic sensitivity of muscle synergies to variations of EMG signals matrix, the reduced set should not alter synergies that come from the initial input, since they provide physiological information on motor coordination. The advantages of such reduced set, in a rehabilitation context, would be the reduction of the inputs processing time, the reduction of the setup bulk and a higher sensitivity to synergy changes after training, which can eventually lead to modifications of the ongoing therapy. In this work, the existence of a minimum muscle set, called optimal set, for an upper-limb myoelectric application, that preserves performance of motor activity prediction and the physiological meaning of synergies, has been investigated. Analyzing isometric contractions during planar reaching tasks, two types of optimal muscle sets were examined: a subject-specific one and a global one. The former relies on the subject-specific movement strategy, the latter is composed by the most recurrent muscles among subjects specific optimal sets and shared by all the subjects. Results confirmed that the muscle set can be reduced to achieve comparable hand force estimation performances. Moreover, two types of muscle synergies namely “Pose-Shared” (extracted from a single multi-arm-poses dataset) and “Pose-Related” (clustering pose-specific synergies), extracted from the global optimal muscle set, have shown a significant similarity with full-set related ones meaning a high consistency of the motor primitives. Pearson correlation coefficients assessed the similarity of each synergy. The discovering of dominant muscles by means of the optimization of both muscle set size and force estimation error may reveal a clue on the link between synergistic patterns and the force task
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