Kemampuan Karbon Aktif Tempurung Kelapa dan Kulit Singkong dalam menurunkan Kadar Logam Berat Kadmium (Cd)pada Limbah Industri Tekstil PT APACINTI CORPORA

industri tekstil merupakan satu dari industri yang menghasilkan limbah dengan kadar Kadmium yang tinggi. kadar Kadmium dalam limbah industri tekstil adalah sebesar 0,7343 mg/L, sedangkan kadar Kadmium menurut KepMenLH no 51 Tahun 1995 tentang Baku Mutu Limbah Cair bagi Limbah Industri adalah 0,05 mg/L. penelitian ini bertujuan untuk mengetahui kemampuan karbon aktif tempurung kelapa dan kulit simgkong sebagai adsorben dalam menurunkan kadar Kadmium pada limbah industri tekstil. jenis penelitian yang digunakan adalah Quasi Experimentaldengan Control group Pretest-postest Design. populasi dalam penelitian ini adalah limbah cair industri tekstil, kemudian sampel yang diambil dari bak penampungan setelah secondary treatment pada Intalasi Pengolahan Air Limbah di industri tekstil tersebut. Test Homogenity of Variancses di dapatkan bahwa levene test 0,52 dengan nilai p value = 0,601, karena nilai p> 0,05 maka ketiga varian adalah sama. analisis data menggunakan analisis Kruskal Wallis. Hasil pada penelitian ini menunjukkan nilai p= 0,0001. karena nilai p<0,05 maka Ho ditolak berarti ada perbedaan rata-rata penurunan kadar Kadmium ketiga variasi adsorben tersebut. jenis adsorben yang paling besar menurunkan kadar Kadmium adalah karbon aktif tempurung kelapa yaitu sebesar 92,4% Kata Kunci: karbon aktif tempurung kelapa, karbon aktif kulit singkong, limbah cai

PERKEMBANGAN PEROLEHAN KECAKAPAN KOMUNIKASI SEORANG SISWA DEAFBLIND DI SLB G/A-B HKI YOGYA

Seorang penyandang deafblind merupakan seorang yang memiliki hambatan pada kedua indera sekaligus yaitu pendengaran dan penglihatan. Salah satu dampak terbesar dari penyandang deafblind adalah keterlambatan dalam perkembangan komunikasi. Tujuan penelitian ini adalah untuk meneliti bagaimana perkembangan perolehan kecakapan komunikasi seorang siswa deafblind. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi kasus. Hasil penelitian menunjukkan bahwa (1) Pada usia 10,5 tahun, S mengalami perkembangan pada 5 aspek komunikasi. (2) Keluarga berperan aktif dalam mengembangkan kecakapan komunikasi S sejak dini. (3) Sekolah memberikan pendampingan yang tepat sejak dini dalam mengembangkan kecakapan komunikasi S . (4). Perkembangan perolehan kecakapan komunikasi yang dialami S dipengaruhi adanya stimulasi berupa pendampingan intensif yang berkesinambungan sejak usia dini sampai saat ini ( usia 10,5 th) dari keluarga dan sekolah. Berdasarkan hasil penelitian, disarankan kepada para guru, keluarga dan profesional yang berkepentingan terhadap pendampingan penyandang deafblind untuk memberikan stimulasi-stimulasi sejak usia dini dan pendampingan yang berkesinambungan dalam mengembangkan kecakapan komunikasinya. Kata Kunci: Perkembangan, Perolehan kecakapan komunikasi, Deafblind. A child with deafblind is someone who has barriers in two senses; hearing and vision. One of the biggest impacts of the deafblind condition is the delay in the communication development. The aim of this study is to examine how the communication skills acquisition of the student who has tottaly deafblind is developed. A qualitative research method is chosen in this case study resulting in (1) At the age of 10.5 years, S, the student who has totally deafblind, has been improving in five aspects of communication. (2) The familly contributes actively in the process of developing his communication skills early on. (3) Schools provide early intervention and provide appropriate mentoring in developing communication skills.(4) the development of communication skills acquisition which is reached by S is influenced by the contributing of family and school who giving early intervention up to now effectively. Based on the results of this study, it is proposed that teachers, families and professionals with an interest towards mentoring people with deafblind to provide stimulations from an early age and continuous mentoring in developing communication skills. Keywords: Development, Communication Skill Acquisition , Deafblin

Peningkatan Hasil Belajar Menganalisis Jenis Kue Indonesia Berbahan Tepung Melalui Penerapan Metode Belajar Pintar Siswa Kelas XI JB 1 SMK Negeri 1 Slahung

Berdasarkan hasil angket sebelum penelitian menunjukkan bahwa sebagian besar siswa akan belajar jika diberi tugas oleh guru. Siswa belum mampu mengambil makna dari belajar, kemauan siswa untuk mengembangkan&nbsp; kreativitasnya masih rendah, kegiatan belajar siswa masih tergantung pada guru. Data yang diperoleh dari daftar nilai diketahui bahwa minat belajar Produk Cake dan Kue Indonesia kompetensi dasar Menganalisis jenis kue Indonesia berbahan tepung sangat rendah, sekitar 70% mendapat nilai dibawah 75. Hal ini ditengarai karena metode pembelajaran yang kurang bervariasi, model pembelajaran yang konvensional dan rendahnya motivasi belajar terhadap mata pelajaran Produk Cake dan Kue Indonesia karena kurang melibatkan siswa secara aktif dalam proses belajar mengajar. Pada kesempatan ini peneliti menawarkan model pembelajaran Belajar PINTAR dengan harapan siswa memahami konsep Menganalisis jenis kue Indonesia berbahan tepung dan memenuhi standar ketuntasan minimal 75%. Penelitian tindakan kelas ini dilaksanakan dalam 3 siklus, terdiri atas 3 pertemuan. Tiap pertemuan terdiri atas 2 x 45 menit. Tiap siklus meliputi kegiatan perencanaan, pelaksanaan, observasi dan refleksi. Data diambil dengan menggunakan instrumen tes, wawancara, angket dan jurnal. Tujuan dari penelitian ini adalah untuk mengetahui peningkatan hasil belajar Produk Cake dan Kue Indonesia melalui Penerapan Metode Belajar PINTAR pada siswa kelas XI JB 1 SMK Negeri 1 Slahung Semester I Tahun Pelajaran 2017/2018. Peranan Model Pembelajaran Belajar PINTAR dalam meningkatkan hasil belajar Produk Cake dan Kue Indonesia ini ditandai adanya peningkatan mean score, yakni : pada siklus I 69,25; siklus II 73,50; dan siklus III 86,50. Selain itu juga ditandai adanya peningkatan persentase ketuntasan belajar, yaitu pada siklus I 45,00%, siklus II menjadi 80,00%, pada siklus III terjadi peningkatan mencapai 100%

Fragile X-associated tremor/ataxia syndrome (FXTAS) in grey zone carriers

The grey zone (GZ; 45–54 CGG repeats in the FMR1 gene) is considered a normal allele; however, several studies have found a high frequency of GZ in movement disordered populations. Here, we describe neurological features of fragile X-associated tremor/ataxia syndrome (FXTAS) in two carriers of GZ alleles, although FXTAS has been defined as occurring only in premutation carriers (55–200 CGG repeats). Both patients had family members who had premutation and were diagnosed with FXTAS. The presence of relatively high GZ alleles with elevated fragile X mental retardation 1 mRNA (FMR1-mRNA) combined with a family history of FXTAS that may represent a facilitating genetic background for FXTAS are the factors that led to the presence of FXTAS in these individuals with a GZ allele. Further research into clinical involvement of GZ alleles is recommended and the definition of FXTAS may require revision

DIVERSIFICATION OF FISHERIES PRODUCTS

Global market and product distribution development make us easy to find various products from other countries in Indonesia. We can find salmon from Europe or Tasmania in any supermarket in Indonesia. Fresh tuna from Indonesia can be found easily in Japan. These global marketing and distribution supported with development in fisheries products. Product diversification is fisheries product that giving value to the product. The value that added to the product makes it marketable and acceptable for consumer in a wider range. This book is delivered for students that study modern fisheries processing technology. This book discuss about diversification from fresh consumed products (fish, shelfish, and others) up to fish based breaded products. Beside describing modern product like sausage, burger, fish stick, etc., we also discuss about popular traditional products like 'pempek' , traditional product from Palembang, South Sumatra. Related processing methods to products diversification are also described as well as discussion about tuna and its derivated productts which are popularly consumed in Japan, famous fresh consumed fish in Japan

Immune-Mediated Disorders Among Women Carriers of Fragile X Premutation Alleles

The relative risk of immune-mediated disorders (IMDs) among women carriers of premutation alleles is estimated by a survey for IMDs among 344 carrier women (age 19–81 years; mean 46.35 and SD12.60) and 72 controls (age 18–87 years; mean 52.40 and SD 15.40). One hundred fifty four (44.77%) women carrier had at least one IMD, as did 20 controls (27.78%). Among women carriers, autoimmune thyroid disorder was the most common (24.4%), then fibromyalgia (10.2%), irritable bowel syndrome (IBS; 9.9%), Raynaud’s phenomenon (7.6%), rheumatoid arthritis (RA; 3.8%), Sjogren syndrome (2.6%), systemic lupus erythematosus (SLE; 2.03%), multiple sclerosis (1.74%). Of 55 carriers age 40 or older with FXTAS, 72.73% had at least one IMD, compared to 46.54% of those without FXTAS (n ¼159), and 31.58% of controls (n ¼57). The estimated odds ratio (OR) for IMD is 2.6 (95% CI 1.2–5.6, P ¼0.015) for women with FXTAS relative to those without FXTAS; the likelihood of IMD in carriers without or with FXTAS was also significantly higher than for controls (OR 2.1, 95% CI 1.1–4.2, P ¼0.034; OR 5.5, 95% CI 2.4–12.5, P <0.001, respectively). Similarly, the odds of having an IMD among carriers with FXPOI is about 2.4 times higher when compared to carriers without FXPOI (95% CI 1.1–5.0; P ¼0.021). The likelihood of IMD in carriers with or without FXPOI is greater (OR 2.4, 95% CI 1.1–5.0; P ¼0.021) compared to that of controls. 2012 Wiley Periodicals, Inc

A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome

Objective: Minocycline rescued synaptic abnormalities and improved behavior in the fragile X mouse model. Previous open-label human studies demonstrated benefits in individuals with fragile X syndrome (FXS); however, its efficacy in patients with FXS has not been assessed in a controlled trial. Method: Randomized, double-blind, placebo-controlled, crossover trial in individuals with FXS, aged 3.5 years to 16 years (n 5 55, mean age 9.2 [SD, 3.6] years). Participants were randomized to minocycline or placebo for 3 months and then switched to the other treatment. Results: Sixty-nine subjects were screened and 66 were randomized. Fifty-five subjects (83.3%) completed at least the first period and 48 (72.7%) completed the full trial. Intention-to-treat analysis demonstrated significantly greater improvements in one primary outcome, Clinical Global Impression Scale—Improvement after minocycline compared with placebo (2.49 6 0.13 and 2.97 6 0.13, respectively, p 5 .0173) and greater improvement in ad hoc analysis of anxiety and mood-related behaviors on the Visual Analog Scale (minocycline: 5.26 cm 6 0.46 cm, placebo: 4.05 cm 6 0.46 cm; p 5 .0488). Side effects were not significantly different during the minocycline and placebo treatments. No serious adverse events occurred on minocycline. Results may be potentially biased by study design weaknesses, including unblinding of subjects when they completed the study, drug-related side effects unblinding, and preliminary efficacy analysis results known to investigators. Conclusions: Minocycline treatment for 3 months in children with FXS resulted in greater global improvement than placebo. Treatment for 3 months appears safe; however, longer trials are indicated to further assess benefits, side effects, and factors associated with a clinical response to minocycline

Sertraline May Improve Language Developmental Trajectory in Young Children with Fragile X Syndrome: A Retrospective Chart Review

Young children with fragile X syndrome (FXS) often experience anxiety, irritability, and hyperactivity related to sensory hyperarousal. However, there are no medication recommendations with documented efficacy for children under 5 years old of age with FXS. We examined data through a chart review for 45 children with FXS, 12–50 months old, using the Mullen Scales of Early Learning (MSEL) for baseline and longitudinal assessments. All children had clinical level of anxiety, language delays based on MSEL scores, and similar early learning composite (ELC) scores at their first visit to our clinic. Incidence of autism spectrum disorder (ASD) was similar in both groups. There were 11 children who were treated with sertraline, and these patients were retrospectively compared to 34 children who were not treated with sertraline by chart review. The baseline assessments were done at ages ranging from 18 to 44 months (mean 26.9, SD 7.99) and from 12 to 50 months (mean 29.94, SD 8.64) for treated and not treated groups, respectively. Mean rate of improvement in both expressive and receptive language development was significantly higher in the group who was treated with sertraline (P<0.0001 and P 0.0071, resp.). This data supports the need for a controlled trial of sertraline treatment in young children with FXS