‘I know you can do all things’1 (Job 42:2) : a literary and theological analysis of Job’s testimony about Yahweh’s sovereignty

The article presents a literary and theological analysis of Job 42:2 as a fitting resolution of the conflicting engagement between Yahweh and Job, which enables both parties to preserve their integrity. The article examines Israel’s testimony about Yahweh’s sovereignty as a background, it analyses Job’s testimony in 42:2 and then demonstrates that this passage probes more deeply into the theology of creation – the inescapable purpose of what God does. The article shows that Job’s testimony about the sovereignty of Yahweh indicates an unusual personality and potent force that is manifested in the events of Job’s life as an agent whose sovereignty is remarkably unlimited. The substance of Job’s testimony this article proposes, produces a dynamic figure that has an overwhelming task at the centre stage of its subject’s well-being. This role, moreover, is the engine that drives Israel’s testimony; the splendour of Israel’s faith and the source of Israel’s life. This role is a theological datum of substance.This research is part of the project ‘Exegesis and the Theology of Isaiah’, directed by Prof. Dr Alphonso Groenewald, Department of Old Testament Studies, Faculty of Theology, University of Pretoria, South AfricaThe article is based on research conducted by B.O.B. for his postdoctoral fellowship at the Department of Old Testament Studies. A.G., co-author of the article, acted as the research leader and corresponding author.http://www.hts.org.za/am2016Old Testament Studie

Use of irradiation hybrids in gene mapping on human chromosome 11

The original objective of the work described in this thesis was the development of genetic and physical mapping resources on human chromosome 11q23 in order to facilitate the positional cloning of a putative locus for Tuberous Sclerosis in that region of the chromosome. To this end I constructed a panel of high dose irradiation hybrids using as a starting point a human-hamster somatic cell hybrid retaining chromosome 11 as its only human material. Forty-seven of the hybrids were characterised in detail by molecular methods and also in some cases by fluorescent in situ hybridisation. A promising hybrid (Jol2) was subcloned further to derive a hybrid containing only 11q23 as its human component. By this time it had become clear that most cases of Tuberous Sclerosis can be accounted for either by mutations at TSCl (9q34) or TSC2 (16p13) and that a locus on chromosome 11, if it exists, must account for very few cases of the disease, making an attempt at positional cloning impractical. The hybrids were therefore used in collaboration with others for the development of region specific probes, some of which were directly useful in the mapping and ultimately the cloning of genes causing ataxia telangiectasia (11q23) and multiple endocrine neoplasia type 1 (11q13). In particular I was able to show that Alu-PCR products from well-characterised hybrids could be used in a rapid and reliable way to obtain regionally defined cosmid clones from the gridded chromosome 11 library available from ICRF. In the course of this work I made use of these and other hybrids to provide new chromosomal localisations for several other genes including those coding for cofilins (CFL1 and CFL2), a fucosyl transferase (FUT4), a retinoic receptor (RXRB) and a mitochondrial NAD-dependent malic enzyme

An account of the printed text of the Greek New Testament : with remarks on its revision upon critical principles. Together with A collation of the critical texts of Griesbach, Scholz, Lachmann, and Tischendorf, with that in common use.

Mode of access: Internet