Thermodynamic dislocation theory of high-temperature deformation in aluminum and steel

The statistical-thermodynamic dislocation theory developed in previous papers is used here in an analysis of high-temperature deformation of aluminum and steel. Using physics-based parameters that we expect theoretically to be independent of strain rate and temperature, we are able to fit experimental stress-strain curves for three different strain rates and three different temperatures for each of these two materials. Our theoretical curves include yielding transitions at zero strain in agreement with experiment. We find that thermal softening effects are important even at the lowest temperatures and smallest strain rates.Comment: 7 pages, 8 figure

Hidden Broad Line Seyfert 2 Galaxies in the CfA and 12micron Samples

We report the results of a spectropolarimetric survey of the CfA and 12micron samples of Seyfert 2 galaxies (S2s). Polarized (hidden) broad line regions (HBLRs) are confirmed in a number of galaxies, and several new cases (F02581-1136, MCG -3-58-7, NGC 5995, NGC 6552, NGC 7682) are reported. The 12micron S2 sample shows a significantly higher incidence of HBLR (50%) than its CfA counterpart (30%), suggesting that the latter may be incomplete in hidden AGNs. Compared to the non-HBLR S2s, the HBLR S2s display distinctly higher radio power relative to their far-infrared output and hotter dust temperature as indicated by the f25/f60 color. However, the level of obscuration is indistinguishable between the two types of S2. These results strongly support the existence of two intrinsically different populations of S2: one harboring an energetic, hidden S1 nucleus with BLR, and the other, a ``pure S2'', with weak or absent S1 nucleus and a strong, perhaps dominating starburst component. Thus, the simple purely orientation-based unification model is not applicable to all Seyfert galaxies.Comment: 5 pages with embedded figs, ApJ Letters, in pres

Large-scale bottleneck effect in two-dimensional turbulence

The bottleneck phenomenon in three-dimensional turbulence is generally associated with the dissipation range of the energy spectrum. In the present work, it is shown by using a two-point closure theory, that in two-dimensional turbulence it is possible to observe a bottleneck at the large scales, due to the effect of friction on the inverse energy cascade. This large-scale bottleneck is directly related to the process of energy condensation, the pile-up of energy at wavenumbers corresponding to the domain size. The link between the use of friction and the creation of space-filling structures is discussed and it is concluded that the careless use of hypofriction might reduce the inertial range of the energy spectrum

Nonmonotonic Trust Management for P2P Applications

Community decisions about access control in virtual communities are non-monotonic in nature. This means that they cannot be expressed in current, monotonic trust management languages such as the family of Role Based Trust Management languages (RT). To solve this problem we propose RT-, which adds a restricted form of negation to the standard RT language, thus admitting a controlled form of non-monotonicity. The semantics of RT- is discussed and presented in terms of the well-founded semantics for Logic Programs. Finally we discuss how chain discovery can be accomplished for RT-.Comment: This paper appears in the proceedings of the 1st International Workshop on Security and Trust Management (STM 2005). To appear in ENTC

Sequence Classification Restricted Boltzmann Machines With Gated Units

For the classification of sequential data, dynamic Bayesian networks and recurrent neural networks (RNNs) are the preferred models. While the former can explicitly model the temporal dependences between the variables, and the latter have the capability of learning representations. The recurrent temporal restricted Boltzmann machine (RTRBM) is a model that combines these two features. However, learning and inference in RTRBMs can be difficult because of the exponential nature of its gradient computations when maximizing log likelihoods. In this article, first, we address this intractability by optimizing a conditional rather than a joint probability distribution when performing sequence classification. This results in the ``sequence classification restricted Boltzmann machine'' (SCRBM). Second, we introduce gated SCRBMs (gSCRBMs), which use an information processing gate, as an integration of SCRBMs with long short-term memory (LSTM) models. In the experiments reported in this article, we evaluate the proposed models on optical character recognition, chunking, and multiresident activity recognition in smart homes. The experimental results show that gSCRBMs achieve the performance comparable to that of the state of the art in all three tasks. gSCRBMs require far fewer parameters in comparison with other recurrent networks with memory gates, in particular, LSTMs and gated recurrent units (GRUs)

Oxidative stress specifically downregulates survivin to promote breast tumour formation.

BackgroundBreast cancer, a heterogeneous disease has been broadly classified into oestrogen receptor positive (ER+) or oestrogen receptor negative (ER-) tumour types. Each of these tumours is dependent on specific signalling pathways for their progression. While high levels of survivin, an anti-apoptotic protein, increases aggressive behaviour in ER- breast tumours, oxidative stress (OS) promotes the progression of ER+ breast tumours. Mechanisms and molecular targets by which OS promotes tumourigenesis remain poorly understood.ResultsDETA-NONOate, a nitric oxide (NO)-donor induces OS in breast cancer cell lines by early re-localisation and downregulation of cellular survivin. Using in vivo models of HMLE(HRAS) xenografts and E2-induced breast tumours in ACI rats, we demonstrate that high OS downregulates survivin during initiation of tumourigenesis. Overexpression of survivin in HMLE(HRAS) cells led to a significant delay in tumour initiation and tumour volume in nude mice. This inverse relationship between survivin and OS was also observed in ER+ human breast tumours. We also demonstrate an upregulation of NADPH oxidase-1 (NOX1) and its activating protein p67, which are novel markers of OS in E2-induced tumours in ACI rats and as well as in ER+ human breast tumours.ConclusionOur data, therefore, suggest that downregulation of survivin could be an important early event by which OS initiates breast tumour formation