121 research outputs found
Analysis and Discussion of Atmospheric Precursor of European Heat Summers
The prediction of summers with notable droughts and heatwaves on the seasonal scale is challenging, especially in extratropical regions, since their development is not yet fully understood. Thus, monitoring and analysis of such summers are important tasks to close this knowledge gap. In a previous paper, the authors presented hints that extreme summers are connected with specific conditions during the winter-spring transition season. Here, these findings are further discussed and analysed in the context of the Earthâs circulation systems. No evidence for a connection between the North Atlantic Oscillation or the Arctic Oscillation during the winter-spring transition and extremely hot and dry summers is found. However, inspection of the geopotential at 850âhPa shows that a Greenland-North Sea-Dipole is connected with extreme summers in Central Europe. This motivated the introduction of the novel Greenland-North Sea-Dipole-Index, GNDI. However, using this index as predictor would lead to one false alarm and one missed event in the time series analysed (1958â2011). Hints are found that the disturbance of the âdipole-summerâ connection is due to El Niño/Southern Oscillation (ENSO). To consider the ENSO effect, the novel Central European Drought Index (CEDI) has been developed, which is composed of the GNDI and the Bivariate ENSO Time Series Index. The CEDI enables a correct indication of all extremely hot and dry summers between 1958 and 2011 without any false alarm
Increased Sensitivity to Possible Muonium to Antimuonium Conversion
A new experimental search for muonium-antimuonium conversion was conducted at
the Paul Scherrer Institute, Villigen, Switzerland. The preliminary analysis
yielded one event fulfilling all required criteria at an expected background of
1.7(2) events due to accidental coincidences. An upper limit for the conversion
probability in 0.1 T magnetic field is extracted as (90%
CL).Comment: 2 figure
HTT-lowering reverses Huntington's disease immune dysfunction caused by NFÎșB pathway dysregulation
The peripheral immune response is altered in Huntington's disease, but the underlying mechanisms are unclear. Using RNA interference to lower huntingtin levels in leucocytes from patients, TrĂ€ger et al. reverse disease-associated phenotypes including cytokine elevation and transcriptional dysregulation, and argue for a direct effect of mutant huntingtin on NFÎșÎ signallin
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