9 research outputs found

    Kainic acid induces expression of caveolin-1 in activated microglia in rat brain

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    Caveolin-1, a major constituent of caveolae, has been implicated in endocytosis, signal transduction and cholesterol transport in a wide variety of cells. In the present study, the expression of caveolin-1 was examined by immunohistochemistry in rat brain with or without systemic injection of kainic acid (KA). Caveolin-1 immunoreactivity was observed in capillary walls in brains of control rats. From one to seven days after KA injection, caveolin-1 immunoreactivity appeared in activated microglia in the cerebral cortex, hippocampus and other brain regions. The strongest immunoreactivity of microglia was seen after 3 days after KA administration. The expression of caveolin-1 was confirmed by RT-PCR and Western blot analysis, respectively. The induction of caveolin-1 expression in microglia activated in response to kainic acid administration suggests its possible role in a modulation of inflammation. (Folia Histochemica et Cytobiologica 2013, Vol. 51, No. 1, 25–30

    An image sensor with fast extraction of objects\u27 positions - Rough vision processor

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    金沢大学大学院自然科学研究科情報システム金沢大学工学部An integration of the signal processing circuits with the image acquiring device, which is called the vision chip and can process information in parallel, is proposed for fast image processing. In applications for robot vision, not only the detailed information, such as shape or texture, but also the rough information, such as \u27something is around here\u27, are important and useful. We consider the detecting of centroids of objects in the focal plain as the rough vision processing, which is useful in practical application, and describe its implementation using two components; the centroid detector and the coordinate generator. First, we describe the fast flag generation algorithm indicating the centroid of objects, and its implementation using an analog parallel signal processing architecture. Next, we describe a novel encoding algorithm for flag positions indicating the centroids in order to obtain their coordinates

    Immunohistochemical Study of [D-Ala2] deltorphin I in Rat Retina

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