10 research outputs found
The Impact of Curated Educational Videos on Pathology Health Literacy for Patients with a Pancreatic, Colorectal, or Prostate Cancer Diagnosis
- Author
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2022
- Field of study
Despite patients having increased access to their own electronic health record (EHR) in recent times, patients are often still not considered a primary audience of pathology reports. An alternative to in-person patient education is the use of multimedia programming to enhance health literacy. Curated video presentations designed to explain diagnosis-specific pathology terms were reviewed by a board-certified pathologist and oncologist team and then shown to patients with a primary diagnosis of either pancreatic, colorectal, or prostate cancer in-clinic; these patients then completed a secure electronic survey immediately afterwards. Seventy patients were surveyed, with 91% agreeing or strongly agreeing that the video they watched increased their understanding of the medical terms used in their pathology reports, with a corresponding average Likert score (ALS) of 4.21 (SD = 0.77, CI = ± 0.18). Furthermore, 95% agreed or strongly agreed that the video they watched both enhanced their understanding of the role of the pathologist in diagnosing cancer (ALS = 4.27; SD = 0.65, CI = ± 0.15) and reported they found the video useful (ALS = 4.27; SD = 0.53, CI = ± 0.13). Curated videos such as those utilized in this study have the potential to increase patient health literacy and inform patients of the multidisciplinary nature of cancer diagnosis
Uveal melanoma presenting as panophthalmitis in the absence of an intraocular mass
- Publication venue
- Henry Ford Health Scholarly Commons
- Publication date
- 26/10/2021
- Field of study
The Impact of Curated Educational Videos on Pathology Health Literacy for Patients with a Pancreatic, Colorectal, or Prostate Cancer Diagnosis
- Author
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Transforming the school workforce: perspectives on school reform in England
- Author
- Ann Lance
- Antony Fielding
- B. Caldwell
- D. Hargreaves
- D. L. Collinson
- E. Hoyle
- E. Hoyle
- G. Butt
- G. Butt
- G. Grace
- Graham Butt
- H. Gunter
- H. M. Gunter
- H. M. Gunter
- H. M. Gunter
- Helen Gunter
- Hywel Thomas
- J. Blackmore
- J. Ozga
- J. Tooley
- J. Tooley
- M. Fullan
- M. Fullan
- M. Fullan
- M. Mac an Ghaill
- M. Wallace
- PricewaterhouseCoopers
- S. J. Ball
- Steve Rayner
- V. Hall
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 23/01/2007
- Field of study
An analytical framework for policy engagement: the contested case of 14–19 reform in England
- Author
- Ainley P.
- Ann Hodgson
- Ball S. J.
- Ball S. J.
- Bowe R.
- Byrne D.
- Clarke J.
- Daugherty R.
- Degregorio C. A.
- Du Gay P.
- Finegold D.
- Gewirtz S.
- Gladwell M.
- Hammersley M.
- Hargreaves D. H.
- Hayward G.
- Higham J.
- Hodgson A.
- Hodgson A.
- Hodgson A.
- Hoggett P.
- Johnson R.
- Ken Spours
- Kogan M.
- Lasonen J.
- Levacic R.
- Newman J.
- Newman J.
- Newman J.
- Ozga J.
- Phillips R.
- Pollard A.
- Pring R.
- Raffe D.
- Silver H.
- Spours K.
- Taylor S.
- Tooley J.
- Whitty G.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
History of research performance measurement systems in the Australian higher education sector
- Author
- Anderson D
- Ann Martin-Sardesai
- Australian Bureau of Statistics (ABS)
- Ball SJ
- Batterham R
- Birmingham S
- Bobe BJ
- Boxall P
- Broadbent J
- Burritt R
- Butler L
- Coaldrake P
- Coffield F
- Cooper B
- Croucher G
- Dawkins JS
- Dawkins JS
- Department of Education Science and Training (DEST)
- Department of Education Science and Training (DEST)
- Department of Foreign Affairs and Trade (DFAT)
- Department of Industry Innovation Science Research and Tertiary Education (DIISR)
- Department of Industry Innovation Science Research and Tertiary Education (DIISR)
- Dudley J
- Dudley J
- Evans E
- Gable A
- Gallagher M
- Guthrie J
- Harman G
- Harman G
- Hoare D
- Howard J
- Howard J
- Howard J
- Howard J
- Hughes O
- James Guthrie
- Johnsen A
- Karpin DSC
- Kemp D
- Kogan M
- Larkins FP
- Laughlin R
- Lucas L
- Lucas L
- Marginson S
- Marginson S
- Martin-Sardesai A
- Miller P
- Nelson B
- Nelson B
- Norton A
- Norton A
- Sally Chaplin
- Schramm C
- Slaughter S
- Smart D
- Smith RHT
- Stuart Tooley
- Tertiary Education Advisory Commission (TEAC)
- Tertiary Education Advisory Commission (TEAC)
- Vidovich L
- Whittington G
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Complement genes contribute sex-biased vulnerability in diverse disorders.
- Author
- Adolfsson Rolf
- Agartz Ingrid
- Agerbo Esben
- Albus Margot
- Alexander Madeline
- Amin Farooq
- Andreassen Ole A
- Bacanu Silviu A
- Begemann Martin
- Belliveau Richard A
- Bene Judit
- Bergen Sarah E
- Bevilacqua Elizabeth
- Bigdeli Tim B
- Black Donald W
- Blackwood Douglas H R
- Boehnke Michael
- Bramon Elvira
- Bruggeman Richard
- Buccola Nancy G
- Buckner Randy L
- Bulik-Sullivan Brendan
- Buxbaum Joseph D
- Byerley William
- Børglum Anders D
- Cahn Wiepke
- Cai Guiqing
- Cairns Murray J
- Campion Dominique
- Cantor Rita M
- Carr Vaughan J
- Carrera Noa
- Catts Stanley V
- Chambert Kimberly D
- Chan Raymond C K
- Chen Eric Y H
- Chen Ronald Y L
- Cheng Wei
- Cheung Eric F C
- Chong Siow Ann
- Cichon Sven
- Clair David St
- Cloninger C Robert
- Cohen David
- Cohen Nadine
- Collier David A
- Consortium Schizophrenia Working Group of the Psychiatric Genomics
- Cormican Paul
- Corvin Aiden
- Craddock Nick
- Crespo-Facorro Benedicto
- Criswell Lindsey A
- Crowley James J
- Curtis David
- Daly Mark J
- Darvasi Ariel
- Davidson Michael
- Davis Kenneth L
- de Haan Lieuwe
- de Rivera Heather
- Degenhardt Franziska
- Del Favero Jurgen
- DeLisi Lynn E
- Demontis Ditte
- Dikeos Dimitris
- Dinan Timothy
- Djurovic Srdjan
- Domenici Enrico
- Donohoe Gary
- Drapeau Elodie
- Duan Jubao
- Dudbridge Frank
- Durmishi Naser
- Ehrenreich Hannelore
- Eichhammer Peter
- Eriksson Johan
- Escott-Price Valentina
- Esko Tõnu
- Essioux Laurent
- Fanous Ayman H
- Farh Kai-How
- Farrell Martilias S
- Frank Josef
- Franke Lude
- Freedman Robert
- Freimer Nelson B
- Friedl Marion
- Friedman Joseph I
- Fromer Menachem
- Gejman Pablo V
- Genovese Giulio
- Georgieva Lyudmila
- Gershon Elliot S
- Giegling Ina
- Gill Michael
- Giusti-Rodríguez Paola
- Godard Stephanie
- Goldstein Jacqueline I
- Golimbet Vera
- Gopal Srihari
- Graham Robert R
- Gratten Jacob
- Gurling Hugh
- Hamshere Marian L
- Handsaker Robert E
- Hansen Mark
- Hansen Thomas
- Harley John B
- Haroutunian Vahram
- Hartmann Annette M
- Henskens Frans A
- Herms Stefan
- Hirschhorn Joel N
- Hoffmann Per
- Hofman Andrea
- Hollegaard Mads V
- Holmans Peter A
- Hougaard David M
- Huang Hailiang
- Hultman Christina M
- Ikeda Masashi
- Iwata Nakao
- Jablensky Assen V
- Joa Inge
- Julià Antonio
- Jönsson Erik G
- Kahn René S
- Kalaydjieva Luba
- Kamitaki Nolan
- Karachanak-Yankova Sena
- Karjalainen Juha
- Kaufman Kenneth M
- Kavanagh David
- Keller Matthew C
- Kelly Brian J
- Kendler Kenneth S
- Kennedy James L
- Keong Jimmy Lee Chee
- Khrunin Andrey
- Kim Yunjung
- Kimberly Robert P
- Kirov George
- Klovins Janis
- Knight Jo
- Knowles James A
- Konte Bettina
- Kucinskas Vaidutis
- Kucinskiene Zita Ausrele
- Kuzelova-Ptackova Hana
- Kähler Anna K
- Langefeld Carl D
- Laurent Claudine
- Lee Phil
- Lee S Hong
- Legge Sophie E
- Lencz Todd
- Lerer Bernard
- Levinson Douglas F
- Li Miaoxin
- Li Qingqin S
- Li Tao
- Liang Kung-Yee
- Lieberman Jeffrey
- Limborska Svetlana
- Liu Jianjun
- Loohuis Loes M Olde
- Loughland Carmel M
- Lubinski Jan
- Lönnqvist Jouko
- Macek Milan
- Magnusson Patrik K E
- Maher Brion S
- Maier Wolfgang
- Malhotra Anil K
- Mallet Jacques
- Marsal Sara
- Mattheisen Manuel
- Mattingsdal Morten
- McCarley Robert W
- McCarroll Steven A
- McCarroll Steven A
- McDonald Colm
- McIntosh Andrew M
- McQuillin Andrew
- Meier Sandra
- Meijer Carin J
- Melegh Bela
- Melle Ingrid
- Mesholam-Gately Raquelle I
- Metspalu Andres
- Michie Patricia T
- Milani Lili
- Milanova Vihra
- Mitjans Marina
- Mokrab Younes
- Moran Jennifer L
- Morris David L
- Morris Derek W
- Mors Ole
- Mortensen Preben B
- Mowry Bryan J
- Murphy Kieran C
- Murray Robin M
- Myin-Germeys Inez
- Müller-Myhsok Bertram
- Neale Benjamin M
- Nelis Mari
- Nenadic Igor
- Nertney Deborah A
- Nestadt Gerald
- Nicodemus Kristin K
- Nikitina-Zake Liene
- Nisenbaum Laura
- Nordin Annelie
- Nöthen Markus M
- O'Callaghan Eadbhard
- O'Donovan Michael C
- O'Dushlaine Colm
- O'Neill F Anthony
- Oh Sang-Yun
- Olincy Ann
- Olsen Line
- Ophoff Roel A
- Ophoff Roel A
- Owen Michael J
- Palotie Aarno
- Pantelis Christos
- Papadimitriou George N
- Parkhomenko Elena
- Pato Carlos N
- Pato Carlos N
- Pato Michele T
- Pato Michele T
- Paunio Tiina
- Pejovic-Milovancevic Milica
- Perkins Diana O
- Pers Tune H
- Petryshen Tracey L
- Pietiläinen Olli
- Pimm Jonathan
- Pocklington Andrew J
- Posthuma Danielle
- Powell John
- Price Alkes
- Pulver Ann E
- Purcell Shaun M
- Quested Digby
- Rasmussen Henrik B
- Reichenberg Abraham
- Reimers Mark A
- Richards Alexander L
- Rietschel Marcella
- Riley Brien P
- Ripke Stephan
- Roffman Joshua L
- Roussos Panos
- Ruderfer Douglas M
- Rujescu Dan
- Salomaa Veikko
- Sanders Alan R
- Schall Ulrich
- Schubert Christian R
- Schulze Thomas G
- Schwab Sibylle G
- Scolnick Edward M
- Scott Rodney J
- Seidman Christine E
- Seidman Larry J
- Sekar Aswin
- Sham Pak C
- Shi Jianxin
- Sigurdsson Engilbert
- Silagadze Teimuraz
- Silverman Jeremy M
- Sim Kang
- Sklar Pamela
- Slominsky Petr
- Smoller Jordan W
- So Hon-Cheong
- Spencer Chris C A
- Stahl Eli A
- Stefansson Hreinn
- Stefansson Kari
- Steinberg Stacy
- Steixner Agnes A
- Stogmann Elisabeth
- Straub Richard E
- Strengman Eric
- Strohmaier Jana
- Stroup T Scott
- Subramaniam Mythily
- Sullivan Patrick F
- Suvisaari Jaana
- Svrakic Dragan M
- Szatkiewicz Jin P
- Söderman Erik
- Taylor Kimberly E
- Thirumalai Srinivas
- Tombleson Philip
- Toncheva Draga
- Tooley Katherine
- Tooney Paul A
- Tosato Sarah
- Van Os Jim
- Veijola Juha
- Visscher Peter M
- Vyse Timothy J
- Waddington John
- Walsh Dermot
- Walters James T R
- Wang Dai
- Wang Qiang
- Webb Bradley T
- Weinberger Daniel R
- Weiser Mark
- Wendland Jens R
- Werge Thomas
- Whelan Christopher W
- Wildenauer Dieter B
- Williams Nigel M
- Williams Stephanie
- Witt Stephanie H
- Wolen Aaron R
- Wong Emily H M
- Wormley Brandon K
- Wray Naomi R
- Wu Jing Qin
- Xi Hualin Simon
- Zai Clement C
- Zheng Xuebin
- Zimprich Fritz
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 11/05/2021
- Field of study
Many common illnesses, for reasons that have not been identified, differentially affect men and women. For instance, the autoimmune diseases systemic lupus erythematosus (SLE) and Sjögren's syndrome affect nine times more women than men1, whereas schizophrenia affects men with greater frequency and severity relative to women2. All three illnesses have their strongest common genetic associations in the major histocompatibility complex (MHC) locus, an association that in SLE and Sjögren's syndrome has long been thought to arise from alleles of the human leukocyte antigen (HLA) genes at that locus3-6. Here we show that variation of the complement component 4 (C4) genes C4A and C4B, which are also at the MHC locus and have been linked to increased risk for schizophrenia7, generates 7-fold variation in risk for SLE and 16-fold variation in risk for Sjögren's syndrome among individuals with common C4 genotypes, with C4A protecting more strongly than C4B in both illnesses. The same alleles that increase risk for schizophrenia greatly reduce risk for SLE and Sjögren's syndrome. In all three illnesses, C4 alleles act more strongly in men than in women: common combinations of C4A and C4B generated 14-fold variation in risk for SLE, 31-fold variation in risk for Sjögren's syndrome, and 1.7-fold variation in schizophrenia risk among men (versus 6-fold, 15-fold and 1.26-fold variation in risk among women, respectively). At a protein level, both C4 and its effector C3 were present at higher levels in cerebrospinal fluid and plasma8,9 in men than in women among adults aged between 20 and 50 years, corresponding to the ages of differential disease vulnerability. Sex differences in complement protein levels may help to explain the more potent effects of C4 alleles in men, women's greater risk of SLE and Sjögren's syndrome and men's greater vulnerability to schizophrenia. These results implicate the complement system as a source of sexual dimorphism in vulnerability to diverse illnesses
Recent Literature in Discovery History
- Author
- ABBOTT CARL
- ADAMS THOMAS
- AHLGREN DOROTHY
- ALLABY IAN
- ANGSTADT GWENDOLYN ANN
- Astrolabe Discovered off Newfoundland Coast
- BARNETT LE ROY
- BETTS ROBERT B
- BONINGTON CHRIS
- BRASWELL LAUREL
- BREMER RICHARD G
- BROC NUMA
- BROWN WALTER C
- CARTER BLUE. CLARK
- CARTER BLUE. CLARK
- CHAMBERS KEITH S
- CHUINARD E. G
- CUMMING WILLIAM P
- DAHL EDWARD
- DAVIS RICHARD CLARK
- DE VORSEY LOUIS
- DILKE O. A. W
- EHRENBERG RALPH E
- EKBERG CARL J
- FENTON EDWARD
- GIBSON GEORGE RUTLEDGE
- GOLE SUSAN
- HAGUE HARLAN
- HERBST PHILIP
- HERVE. THERY
- KARAMANSKI THEODORE J
- KAYE BARRY
- KAZYMYRA-DZIOBA NADIA
- KEDDIE GRANT R
- KEJLBO IB RONNE
- KERNAGHAN LOIS D
- KIDD BETTY
- KINNIBURGH IAN A. G
- LAMONTAGNE ROLAND
- LANGELIER GILLES
- LANKIEWICZ DONALD P
- LAPEROUSE JEAN FRANCOIS
- LEE ROBERT E
- LEWIS BRENDA R
- LEWIS CLIFFORD M. S. J
- LINCOLN A
- LINCOLN A
- Louis XVI donne ses instructions au Capitaine de Vaisseau de Lapérousse. [Notes on a painting.]
- MANFRED. BUTTNER
- MARCEL. DESTOMBES
- MARDIN OSMAN
- MARSHALL P. J
- MARSHALL-CORNWALL JAMES
- MARTIN ROBERT S
- MOORE CHRISTOPHER
- MORRISON WALTER
- O'DONNELL JAMES HOWLETT
- PARKER JOHN
- PATRICK ELIZABETH NELSON
- PIERCE HENRY H
- QUINN DAVID B.
- RANDALL GLENN
- RAY JEAN M
- RAYMOND WOOD W.
- RICHARDSON W. A. R
- RONAN CHARLES E
- RONDA JAMES P
- ROSTENBERG LEONA
- SAINDON BOB
- TEIXEIRA DA MOTA A
- THOMAS STEPHEN D
- THROWER NORMAN J. W
- THURMAN MELBURN D
- TOOLEY R. V
- VERLINDEN CHARLES
- WALLIS HELEN
- WAWN ANDREW
- WAYNE ORCHISTON D.
- WOLTER JOHN A
- WOODWARD DAVID
- WOODWARD DAVID
- WOODWARD FRANCES
- WOODWARD FRANCES
- Publication venue
- 'Maney Publishing'
- Publication date
- Field of study
ACKNOWLEDGMENTS AND REFERENCES
- Author
- Adair Mary J
- Adair Mary J
- Adair Mary J
- Adrien Hannus L.
- Ahler Stanley A.
- Ahler Stanley A.
- Alex Lynn M
- Alex Lynn M
- American Fisheries Society
- Anderson Duane C
- Anderson Duane C
- Anderson Duane C
- Anderson Duane C.
- Anderson Paul F
- Anonymous
- Anonymous
- Arzigian Constance
- Arzigian Constance M.
- Asch David L
- Asch David L.
- Asch David L.
- Asch David L.
- Asch David L.
- Asch Nancy B.
- Aufderheide Arthur C
- Bach Daniel R
- Baerreis David A
- Baerreis David A.
- Bailey Reeve M.
- Bamforth Douglas B
- Bass William M
- Bass William M.
- Beckwith Martha Warren
- Benn David W
- Benn David W
- Benn David W
- Benn David W
- Benn David W
- Benn David W
- Benn David W
- Benn David W
- Benn David W.
- Bennett John W
- Betancourt Phil P
- Bettis E. Arthur
- Betts Colin M
- Billeck William T
- Bird Robert McK.
- Birk Douglas
- Blaine Martha Royce
- Blaine Martha Royce
- Blake Leonard W
- Blake Leonard W
- Blake Leonard W.
- Blake Leonard W.
- Blakeslee Donald J
- Blakeslee Donald J.
- Bluhm Elaine A
- Boszhardt Robert F
- Boszhardt Robert F
- Boszhardt Robert F
- Boszhardt Robert F.
- Bowers Alfred W
- Bowers Alfred W
- Bowles John B
- Bozell John R
- Bray Robert T
- Bray Robert T
- Brown James A.
- Brown Lloyd A
- Buikstra Jane E
- Buikstra Jane E.
- Burke-Gaffney Michael W
- Callahan Kevin L
- Catlin George
- Chapman Carl H
- Chapman Carl H
- Chapman Carl H.
- Charlevoix
- Christiansen Paul
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- Clark W.P
- Cleary Robert E
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- Cleland Charles E.
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- Cummings Kevin S.
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- Dorsey James Owen
- Dorsey James Owen
- Dorsey James Owen
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- du Terrage Villiers
- Ehrenberg Ralph E
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- Emerson Thomas E.
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- Eric Hollinger R.
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- Fundaburk Emma Lila
- Gallagher James P
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- Gallatin Albert
- Gilmore Melvin R
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- Grantham Larry
- Great Plains Flora Association
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- Holth Kari
- Howard James H
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- Hubert Smith G.
- Hubert Smith G.
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- Hunter Andrea A.
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- Hyde S.C
- Jablow Joseph
- Jablow Joseph
- Jackson H. Edwin
- Jackson Laura Spess
- James Edwin
- Jans-Langel Carmen
- Jantz Richard L
- Jantz Richard L.
- Jean-Baptiste Bénard de la Harpe
- Johnson Alfred E
- Johnson Craig M
- Jones Clyde
- Jones J. Knox
- Kay Marvin
- Kelly John E
- Key Patrick J
- Keyes Charles R
- Keyes Charles R
- Kindscher Kelly
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- King Frances B
- King Frances B
- Kingsbury George W
- Klippel Walter E
- Kris Hirst K.
- Kullen Douglas
- Kurtz William M
- La Flesche Francis
- La Flesche Francis
- La Flesche Francis
- Layrisse M.
- Lee David S.
- Lehmer Donald J
- Lehmer Donald J
- Lillie Robin
- Lincoln
- Lincoln Frederick C
- Logan Brad
- Logan Brad
- Lopinot Neal
- Lorenzini Michele
- Loring Brace C.
- Ludwickson John
- Lueck Edward J. R.
- Lurie Rochelle
- Malcolm Lewis G.
- Malcolm Lewis G.
- Malcolm Lewis G.
- Mann Charles C
- Mann Robert W.
- Margry Pierre
- Marriott Alice
- Martin Alexander C.
- Mason Carol
- Mason Ronald J
- McKenney Thomas L.
- McKusick Marshall
- McLaughlin Marie L
- McQuay Jerry
- Michlovic Michael G
- Miewald Christiana E
- Miller Naomi F.
- Miner William Harvey
- Moerman Daniel E
- Molyneaux Brian Leigh
- Molyneaux Brian Leigh
- Monckton Stephen G
- Montgomery F. H
- Mooney James
- Mooney James
- Moore John H
- Morrow Toby
- Mott Mildred
- Munsell Color
- Myer William E
- Nasatir Abraham P
- Nasatir Abraham P
- Neill Edward Duffield
- Nickel Robert K
- Nickel Robert K
- Nicollet Joseph N
- Nolan David J.
- Norall Frank
- Nuttall Thomas
- Orr Ellison
- Orr Ellison
- Orr Ellison
- Ortner Donald J.
- Over W.H.
- Overstreet David F
- Overstreet David F
- Overstreet David F
- Overstreet David F
- Overstreet David F
- Owsley Douglas W.
- Owsley Douglas W.
- O’Brien Michael J
- O’Brien Michael J
- O’Gorman Jodie A.
- O’Shea John M
- O’Shea John M
- Pammel L. H.
- Parker Kathryn E
- Parks Douglas R
- Parks Douglas R
- Parks Douglas R
- Parks Douglas R.
- Pauketat Timothy R
- Pauketat Timothy R
- Pauketat Timothy R.
- Pearsall Deborah M.
- Perino Gregory H
- Pettigrew Frederick W
- Pettigrew Frederick W
- Pettigrew Frederick W
- Picha Paul R
- Platt Mrs. E. G.
- Pollack David
- Pond G.H.
- Pond Samuel W
- Porter James W
- Potter William L
- Prior Jean C
- Quimby George
- Rae Johns M.
- Raemsch Carol A
- Raymond Wood W.
- Raymond Wood W.
- Raymond Wood W.
- Raymond Wood W.
- Raymond Wood W.
- Raymond Wood W.
- Raymond Wood W.
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- Reinhard Karl J.
- Riggs Stephen R
- Riggs Stephen R
- Riggs Stephen R
- Riggs Stephen R
- Riggs Stephen R
- Riggs Stephen R
- Ritchie William A
- Ritterbush Lauren W
- Ritterbush Lauren W
- Ritterbush Lauren W
- Robinson Doane
- Robinson Doane
- Robinson Doane
- Rodell Roland L
- Rodell Roland L
- Roger Conant
- Rood Ronald J
- Royce Charles C.
- Salzer Robert J
- Salzer Robert J
- Santure Sharron K
- Santure Sharron K.
- Sasso Robert F
- Saunders Lorraine P.
- Schermer Shirley J
- Schermer Shirley J
- Schermer Shirley J
- Schermer Shirley J.
- Schneider Fred
- Schoolcraft Henry R
- Schroeder Maijorie
- Scott Douglas D.
- Semken Holmes A.
- Shea John Gilmary
- Shennan Stephen
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- Wedel Waldo R
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- Wegner Steven A.
- Weltfish Gene
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- White Richard
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- Whitman William
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- Will George F
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Delayed colorectal cancer care during covid-19 pandemic (decor-19). Global perspective from an international survey
- Author
- Abary Ryan Rainiel A
- Abdelwahab Khaled M Egypt
- Abellán Antonio M Spain
- Abraham Ned Australia
- Achkasov Sergey I Russia
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- Stevenson Andrew RL Australia
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- Sutton Jeffrey M USA
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- Sweden
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- UK
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- USA
- USA
- USA
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- Voutsarakis Athanasios UK
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- Wang Xiaofeng China
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- Xiaoqiang Jia China
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- Yanishev Alexey Russia
- Yildirim Ali C Turkey
- Yildiz Alp Turkey
- Yildiz Ufukmete Turkey
- Yilmaz Mehmet Turkey
- Younis Muhammad Umar MUY UAE
- Yousef Zeyad Saudi Arabia
- Yu Dongsheng China
- Zalucki James USA
- Zaman Ahamaduz Bangladesh
- Zamora Aída T Spain
- Zampitis Nikolaos Cyprus
- Zanus Giacomo Italy
- Zapata Gonzalo H Argentina
- Zelic Marko Croatia
- Zenger Serkan Turkey
- Zheng Jianyong China
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- Zmora Oded Israel
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- Zorcolo Luigi Italy
- Zucchella Martino Italy
- Zuhdy Mohammad
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Background
The widespread nature of coronavirus disease 2019 (COVID-19) has been unprecedented. We sought to analyze its global impact with a survey on colorectal cancer (CRC) care during the pandemic.
Methods
The impact of COVID-19 on preoperative assessment, elective surgery, and postoperative management of CRC patients was explored by a 35-item survey, which was distributed worldwide to members of surgical societies with an interest in CRC care. Respondents were divided into two comparator groups: 1) ‘delay’ group: CRC care affected by the pandemic; 2) ‘no delay’ group: unaltered CRC practice.
Results
A total of 1,051 respondents from 84 countries completed the survey. No substantial differences in demographics were found between the ‘delay’ (745, 70.9%) and ‘no delay’ (306, 29.1%) groups. Suspension of multidisciplinary team meetings, staff members quarantined or relocated to COVID-19 units, units fully dedicated to COVID-19 care, personal protective equipment not readily available were factors significantly associated to delays in endoscopy, radiology, surgery, histopathology and prolonged chemoradiation therapy-to-surgery intervals. In the ‘delay’ group, 48.9% of respondents reported a change in the initial surgical plan and 26.3% reported a shift from elective to urgent operations. Recovery of CRC care was associated with the status of the outbreak. Practicing in COVID-free units, no change in operative slots and staff members not relocated to COVID-19 units were statistically associated with unaltered CRC care in the ‘no delay’ group, while the geographical distribution was not.
Conclusions
Global changes in diagnostic and therapeutic CRC practices were evident. Changes were associated with differences in health-care delivery systems, hospital’s preparedness, resources availability, and local COVID-19 prevalence rather than geographical factors. Strategic planning is required to optimize CRC care