363 research outputs found
A Sequence-to-Sequence&Set Model for Text-to-Table Generation
Recently, the text-to-table generation task has attracted increasing
attention due to its wide applications. In this aspect, the dominant model
formalizes this task as a sequence-to-sequence generation task and serializes
each table into a token sequence during training by concatenating all rows in a
top-down order. However, it suffers from two serious defects: 1) the predefined
order introduces a wrong bias during training, which highly penalizes shifts in
the order between rows; 2) the error propagation problem becomes serious when
the model outputs a long token sequence. In this paper, we first conduct a
preliminary study to demonstrate the generation of most rows is
order-insensitive. Furthermore, we propose a novel sequence-to-sequence&set
text-to-table generation model. Specifically, in addition to a text encoder
encoding the input text, our model is equipped with a table header generator to
first output a table header, i.e., the first row of the table, in the manner of
sequence generation. Then we use a table body generator with learnable row
embeddings and column embeddings to generate a set of table body rows in
parallel. Particularly, to deal with the issue that there is no correspondence
between each generated table body row and target during training, we propose a
target assignment strategy based on the bipartite matching between the first
cells of generated table body rows and targets. Experiment results show that
our model significantly surpasses the baselines, achieving state-of-the-art
performance on commonly-used datasets
Immunopathogenesis of Behcet's Disease
Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions, ocular lesions, and other manifestations. Although the pathogenesis of BD is unclear, some studies have shown that immunological aberrations play an important role in the development and progression of BD. Infection-related trigger factors, including antigens and autoantigens, are believed to mediate the development of BD in patients with a genetic predisposition and subsequently activate the innate and adaptive immune systems, resulting in the production of numerous cytokines and chemokines to combat the infection-related factors. The study of the immunological mechanism of BD paves the way for the development of innovative therapies. Recently, novel biotherapy approaches, including interferon-α (IFN-α), tumor necrosis factor-α (TNF-α) antagonists, and other agents that target interleukins and their receptors, have shown promising results in the treatment of patients with refractory BD and have improved the prognosis of BD. In this review, we provide the current concepts of BD immunopathogenesis
[μ-Bis(trimethylsilyl)amido]bis[μ-N,N-dimethyl-N′,N′′-bis(trimethylsilyl)guanidinato]-triangulo-tricopper(I)
The title compound, [Cu3(C6H18NSi2)(C9H24N3Si2)2], is a trinuclear CuI complex. A crystallographic twofold axis passes through one CuI atom and the N atom of the bis(trimethylsilyl)amide ligand that bridges between the other two CuI atoms. The Cu—Cu bonds bridged by the guanadinate ligands [2.7913 (9) Å] are slightly longer than the Cu—Cu bond bridged by the bis(trimethylsilyl)amide ligand [2.6405 (11) Å]
KAgF3: quasi-one-dimensional magnetism in three-dimensional magnetic ions sublattice
The electronic structure and magnetic properties of the Jahn-Teller-distorted
perovskite KAgF3 have been investigated using the full-potential linerized aug-
mented plane-wave method. It is found that KAgF3 exhibits significant
quasi-one- dimensional antiferromagnetism with the ratio of exchange constant
jJ?j (perpen- dicular to the z axis) and J (along the z axis) about 0.04,
although the sublattice of magnetic ion is three-dimensional. The strong
quasi-one-dimensional antiferromag- netism originates from the
C-antiferro-distortive orbital ordering of the Ag2+ 4d9 ions. The orbital
ordered antiferromagnetic insulating state in KAgF3 is determined by on-site
Coulomb repulsion to a large extent.Comment: 15 pages, 6 figure
Clinical outcome and prognostic factors of patients with non-traumatic angiography-negative subarachnoid hemorrhage
PurposeThe cause of spontaneous subarachnoid hemorrhage (SAH) is unknown in 10% of cases. The aim of this study was to demonstrate the characteristics of patients with angiography-negative subarachnoid hemorrhage (anSAH) and to analyze factors influencing the clinical outcome in patients suffering from anSAH.MethodsA retrospective cohort of 75 patients with anSAH [26 perimesencephalic (pmSAH) and 49 non-perimesencephalic SAH (npmSAH)] admitted between January 2016 and June 2022 was included. We analyzed demographic, clinical data and 6-month functional outcomes. Enter regression analysis was performed to identify factors associated with outcomes.ResultsUnfavorable outcome was achieved in 10 of 75 patients (13.3%). Unfavorable outcome was associated with senior adults (p = 0.008), Hijdra cistern score (HCS) elevation (p = 0.015), long-time lumbar cistern continuous drainage (LCFD; p = 0.029) and hydrocephalus (p = 0.046). The only significant risk factor for unfavorable outcome after npmSAH was the HCS (OR 1.213 (95%CI 1.007–1.462), p = 0.042).ConclusionOur study provides valuable information on both SAH patterns and functional outcome in patients suffering from anSAH and should be taken into consideration during management of these patients
LncRNA-42060 Regulates Tamoxifen Sensitivity and Tumor Development via Regulating the miR-204-5p/SOX4 Axis in Canine Mammary Gland Tumor Cells
Tamoxifen is the drug of choice for endocrine therapy of breast cancer. Its clinical use is limited by the development of drug resistance. There is increasing evidence that long non-coding RNAs (lncRNAs) are associated with tumor drug resistance. Therefore, we established two TAM-resistant cell lines, CHMpTAM and CHMmTAM. The different expression levels of lncRNA and miRNA in CHMmTAM and CHMm were screened by RNA sequencing, and the lncRNA-miRNA interactions were analyzed. LncRNA ENSCAFG42060 (lnc-42060) was found to be significantly upregulated in drug-resistant cells and tumor tissues. Further functional validation revealed that the knockdown of lnc-42060 inhibited proliferation, migration, clone formation, restoration of TAM sensitivity, and reduction of stem cell formation in drug-resistant cells, whereas overexpression of lnc-4206 showed opposite results. Bioinformatics and dual-luciferase reporter gene assays confirmed that lnc-42060 could act as a sponge for miR-204-5p, further regulating SOX4 expression activity and thus influencing tumor cell progression. In conclusion, we screened lncRNAs and miRNAs associated with TAM resistance in canine mammary gland tumor cells for the first time. lnc-42060 served as a novel marker that may be used as an important biomarker for future diagnosis and treatment
Phase shift and magnetic anisotropy induced field splitting of impurity states in (Li1-xFex)OHFeSe superconductor
Revealing the energy and spatial characteristics of impurity induced states
in superconductors is essential for understanding their mechanism and
fabricating new quantum state by manipulating impurities. Here by using
high-resolution scanning tunneling microscopy/spectroscopy, we investigated the
spatial distribution and magnetic field response of the impurity states in
(Li1-xFex)OHFeSe. We detected two pairs of strong in-gap states on the
"dumbbell" shaped defects. They display clear damped oscillations with
different phase shifts and a direct phase-energy correlation. These features
have long been predicted for classical Yu-Shiba-Rusinov (YSR) state, which are
demonstrated here with unprecedented resolution for the first time. Moreover,
upon applying magnetic field, all the in-gap state peaks remarkably split into
two rather than shift, and the splitting strength is field orientation
dependent. Via detailed numerical model calculations, we found such anisotropic
splitting behavior can be naturally induced by a high-spin impurity coupled to
anisotropic environment, highlighting how magnetic anisotropy affects the
behavior of YSR states.Comment: Main text with supplementary (accepted by Phys. Rev. Lett.
Genome-wide characterization of ubiquitin-conjugating enzyme gene family explores its genetic effects on the oil content and yield of Brassica napus
Ubiquitin-conjugating enzyme (UBC) is a critical part of the ubiquitin–proteasome pathway and plays crucial roles in growth, development and abiotic stress response in plants. Although UBC genes have been detected in several plant species, characterization of this gene family at the whole-genome level has not been conducted in Brassica napus. In the present study, 200 putative BnUBCs were identified in B. napus, which were clustered into 18 subgroups based on phylogenetic analysis. BnUBCs within each subgroup showed relatively conserved gene architectures and motifs. Moreover, the gene expression patterns in various tissues as well as the identification of cis-acting regulatory elements in BnUBC promoters suggested further investigation of their potential functions in plant growth and development. Furthermore, three BnUBCs were predicted as candidate genes for regulating agronomic traits related to oil content and yield through association mapping. In conclusion, this study provided a wealth of information on the UBC family in B. napus and revealed their effects on oil content and yield, which will aid future functional research and genetic breeding of B. napus
- …