Letter from Joseph S. Tomlinson to James B. Finley

Dr. Joseph Tomlinson (president of Augusta College in Kentucky) writes to let Finley know there is a strong feeling in Kentucky against the proposed division of the Methodist Episcopal Church. If the southern Methodists should decide on division, Kentucky, Western Virginia and Missouri will stand firm against secession and remain part of the northern church. If we secede with the south, we will be thrown into the arms of heightened proslavery nullifiers and the cause of emancipation will be thrown back to a far greater extent than it has ever been done by Abolitionism. Abstract Number - 803https://digitalcommons.owu.edu/finley-letters/2307/thumbnail.jp

Letter from Joseph S. Tomlinson to Mr. & Mrs. Johnson Armstrong

Joseph S. Tomlinson has just returned from a trip to Maysville, Kentucky, where he stayed in the home of Johnson Armstrong and his wife. He writes a letter of appreciation to his hosts. [At the time, Tomlinson was completing his degree at Transylvania University in Lexington, KY. Graduating in 1825, he was admitted on trial to the Kentucky Conference in September of 1825 and appointed to a professorship at Augusta College in Maysville. Johnson Armstrong was a trustee at the college.] The letter is difficult to read and the author was initially identified as Tolindaw . Comparing the signature in the October 31, 1844 letter, it is clear that both letters were written by Tomlinson. Abstract Number - 534https://digitalcommons.owu.edu/finley-letters/1831/thumbnail.jp

Letter from Joseph S. Tomlinson to James B. Finley

Dr. Joseph Tomlinson (president of Augusta College in Kentucky), tells Finley about the recent successful commencement. He then discusses Augusta\u27s financial and legal difficulties, brought about by the division of the MEC into a northern and southern church. Tomlinson suggests the creation of a Kentucky District within the conference of the Ohio Methodist Episcopal Church. He believes that a large portion of Kentucky Methodist societies would align themselves with the MEC rather than the MEC South. [Note: the state of Kentucky revoked the college\u27s charter on February 26, 1849]. Abstract Number - 638https://digitalcommons.owu.edu/finley-letters/1734/thumbnail.jp

Percutaneous Achilles Tendon Repair Using Ultrasound Guidance: An Intraoperative Ultrasound Technique

Rupture of the Achilles tendon is a common injury seen in patients of varying ages and activity levels. There are many considerations for treatment of these injuries, with both operative and nonoperative management providing satisfactory outcomes in the literature. The decision to proceed with surgical intervention should be individualized for each patient, including the patient\u27s age, future athletic goals, and comorbidities. Recently, a minimally invasive percutaneous approach to repair the Achilles tendon has been proposed as an equivalent alternative to the traditional open repair, while avoiding wound complications associated with larger incisions. However, many surgeons have been hesitant to adopt these approaches due to poor visualization, concern that suture capture in the tendon is not as robust, and the potential for iatrogenic sural nerve injury. The purpose of this Technical Note is to describe a technique using high-resolution ultrasound guidance intraoperatively during minimally invasive repair of the Achilles tendon. This technique minimizes the drawbacks of poor visualization associated with percutaneous repair, while providing the benefit of a minimally invasive approach

Assessing the sociology of sport: On race and diaspora

© The Author(s) 2014 On the 50th anniversary of the ISSA and IRSS, a key foundational scholar on the intersection of race and sport, Ben Carrington, reflects on the field as a whole and the notion of “diaspora” in understanding race and sport. In considering the trajectory of the sociology of sport, questions are raised about whether a coherent field has ever existed. Noting relative failures in getting “mainstream sociology” to take sport seriously, the challenges ahead are for a field that is necessarily a “multifaceted” entity, and one that ironically has never been more impactful while at its weakest institutional moment. Noting the paradox between the relative little consideration given to sport in the main sociology journals in the US and UK in contrast with the sociology of sport having successfully established self-reproducing and self-referencing spaces of critical enquiry, a key challenge for the field continues to be in its search for a “scholarly place;” it is less than clear whether the banner of “the sociology of sport” continues to resonate in the face of the neo-liberal assaults on critical scholarship within higher education. The concept of “diaspora,” surprisingly ignored in the study of sport, will be increasingly important in the future as it will enable critical race scholars to problematize the often Eurocentric and teleological underpinning of globalization theory in relation to sport; considerations of diaspora will fuel more meaningful accounts of how sport reconnects geographically dispersed groups and changes identities and subjectivities in hostile circumstances

SARS Transmission among Hospital Workers in Hong Kong

Despite infection control measures, breakthrough transmission of severe acute respiratory syndrome (SARS) occurred for many hospital workers in Hong Kong. We conducted a case-control study of 72 hospital workers with SARS and 144 matched controls. Inconsistent use of goggles, gowns, gloves, and caps was associated with a higher risk for SARS infection (unadjusted odds ratio 2.42 to 20.54, p < 0.05). The likelihood of SARS infection was strongly associated with the amount of personal protection equipment perceived to be inadequate, having <2 hours of infection control training, and not understanding infection control procedures. No significant differences existed between the case and control groups in the proportion of workers who performed high-risk procedures, reported minor protection equipment problems, or had social contact with SARS-infected persons. Perceived inadequacy of personal protection equipment supply, infection control training <2 hours, and inconsistent use of personal protection equipment when in contact with SARS patients were significant independent risk factors for SARS infection

Human Metapneumovirus-associated Atypical Pneumonia and SARS

Acute pneumonia developed in a previously healthy man during the outbreak of severe acute respiratory syndrome (SARS) in southern China in March 2003. Antibiotic treatment was ineffective, and he died 8 days after illness onset. Human metapneumovirus was isolated from lung tissue. No other pathogen was found. Other etiologic agents should thus be sought in apparent SARS cases when coronavirus infection cannot be confirmed

Severe Acute Respiratory Syndrome–associated Coronavirus Infection

Whether severe acute respiratory syndrome–associated coronavirus (SARS-CoV) infection can be asymptomatic is unclear. We examined the seroprevalence of SARS-CoV among 674 healthcare workers from a hospital in which a SARS outbreak had occurred. A total of 353 (52%) experienced mild self-limiting illnesses, and 321 (48%) were asymptomatic throughout the course of these observations. None of these healthcare workers had antibody to SARS CoV, indicating that subclinical or mild infection attributable to SARS CoV in adults is rare

Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH Mutations in Glioblastoma

Isocitrate dehydrogenases (IDHs) catalyse oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG). IDH1 functions in the cytosol and peroxisomes, whereas IDH2 and IDH3 are both localized in the mitochondria. Heterozygous somatic mutations in IDH1 occur at codon 132 in 70% of grade II–III gliomas and secondary glioblastomas (GBMs), and in 5% of primary GBMs. Mutations in IDH2 at codon 172 are present in grade II–III gliomas at a low frequency. IDH1 and IDH2 mutations cause both loss of normal enzyme function and gain-of-function, causing reduction of α-KG to D-2-hydroxyglutarate (D-2HG) which accumulates. Excess hydroxyglutarate (2HG) can also be caused by germline mutations in D- and L-2-hydroxyglutarate dehydrogenases (D2HGDH and L2HGDH). If loss of IDH function is critical for tumourigenesis, we might expect some tumours to acquire somatic IDH3 mutations. Alternatively, if 2HG accumulation is critical, some tumours might acquire somatic D2HGDH or L2HGDH mutations. We therefore screened 47 glioblastoma samples looking for changes in these genes. Although IDH1 R132H was identified in 12% of samples, no mutations were identified in any of the other genes. This suggests that mutations in IDH3, D2HGDH and L2HGDH do not occur at an appreciable frequency in GBM. One explanation is simply that mono-allelic IDH1 and IDH2 mutations occur more frequently by chance than the bi-allelic mutations expected at IDH3, D2HGDH and L2HGDH. Alternatively, both loss of IDH function and 2HG accumulation might be required for tumourigenesis, and only IDH1 and IDH2 mutations have these dual effects