The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade

<p>Abstract</p> <p>Background</p> <p>The association between excess body weight, impairment of health and different co-morbidities is well recognized; however, little is known on how excess body weight may affect the quality of life in the general population. Our study investigates the relationship between perceived health-related quality of life (HRQL) and body mass index (BMI) in the urban population of Belgrade.</p> <p>Methods</p> <p>The research was conducted during 2005 on a sample of 5,000 subjects, with a response of 63.38%. The study sample was randomly selected and included men and women over 18 years of age, who resided at the same address over a period of 10 years. Data were collected by means of a questionnaire and nutritional status was categorized using the WHO classification. HRQL was measured using the SF-36 generic score. Logistic regression analysis was used to compare HRQL between subjects with normal weight and those with different BMI values; we monitored subject characteristics and potential co-morbidity.</p> <p>Results</p> <p>The prevalence of overweight males and females was 46.6% and 22.1%, respectively. The prevalence of obesity was 7.5% in males and 8.5% in females.</p> <p>All aspects of health, except mental, were impaired in males who were obese. The physical and mental wellbeing of overweight males was not significantly affected; all score values were similar to those in subjects with normal weight.</p> <p>By contrast, obese and overweight females had lower HRQL in all aspects of physical functioning, as well as in vitality, social functioning and role-emotional.</p> <p>Conclusion</p> <p>The results of our study show that, in the urban population of Belgrade, increased BMI has a much greater impact on physical rather than on mental health, irrespective of subject gender; the effects were particularly pronounced in obese individuals.</p

Proizvodne osobine i kvalitet ploda novointrodukovanih sorti jagode

The paper presents results of the research into productive qualities and fruit quality of the ‘Clery, ‘Joly’ and ‘Dely’ strawberry cultivars, conducted during 2012 and 2013. The fruit mass and yield per crown were significantly higher in the ‘Joly’ cultivar. A significantly higher number of fruits per crown and higher yield per crown were recorded in the second year of harvest, whereas the fruit mass was significantly higher in the first year. The highest values of fruit quality parameters (RSM and total acidity) were recorded in the ‘Joly’ cultivar, whereas the highest values of the total sugars, pH and the RSM/total acidity ratio were recorded in the ‘Dely’ cultivar. A better chemical composition of the fruit of the examined cultivars was determined in 2012. In the overall result, the ‘Joly’ cultivar demonstrated the best productive qualities, whereas the ‘Dely’ cultivar was superior from the aspect of the fruit quality.U radu su prikazani rezultati dvogodišnjih proučavanja (2012−2013.) proizvodnih osobina i kvaliteta ploda jagode sorti ‘Clery’, ‘Joly’ i ‘Dely’. Vrednosti mase ploda i prinosa po bokoru bile su značajno veće kod sorte ‘Joly’. Značajno veći broj plodova po bokoru i prinos po bokoru zabeležen je u drugoj godini plodonošenja, dok je masa ploda bila značajno veća u prvoj godini. Najveće vrednosti parametara kvaliteta ploda (rastvorljiva suva materija i ukupna kiselost), zabeležene su kod sorte ‘Joly’, dok su najveće vrednosti sadržaja ukupnih šećera, pH i odnosa RSM/UK zabeležene kod sorte ‘Dely’. Hemisjki sastav ploda, svih proučavanih sorti, bio je izraženiji u 2012. godini. Ukupno posmatrano, najbolja proizvodna svojstva ispoljila je sorta ‘Joly’, dok je sa stanovišta kvaliteta ploda, superiornost pokazala sorta ‘Dely’

PHYSICAL AND CHEMICAL PROPERTIES OF SOIL IN FRUIT GROWING AREA TOPOLA (SERBIA)

The aim of the investigation was to assess the level of soil fertility and repair measures in order to enhance the productivity of fruit production in a traditional fruit growing area. (Municipality of Topola, Serbia). The following tests were performed: mechanical composition, physical and chemical properties of soil, total adsorbed base cation, capacity of adsorbed base cation, degree of base saturation, different types of soil acidity, contents of carbon, humus, total nitrogen, easily accessible forms of P2O5 and K2O. Results obtained have shown that soils from all studied sites are of “heavy” mechanical texture with 75,40-84,90% of physical clay. High capacity of cation adsorption, low to medium hydrolytic acidity and high to almost complete saturation of adsorbed bases, has been measured. In compliance with previous analyses, it has been assessed that soils are neutral and of low acid chemical reaction, with low carbon and medium humus content and total nitrogen. Easily accessible content of P2O5 and K2O varies depending on the food quantity on individual parcels with low to medium accessibility to parcels with no fruit plantations. Based on the parameters analysed, the tested soils demand repair of mechanical properties, which will facilitate greater nutrient uptake

Influence of fertigation on generative potential and pomological properties of different apple cultivars

The paper presents an investigation into the influence of fertigation on generative potential parameters and pomological properties of apple fruits. The study was done in apple orchard of Fruit Research Institute Cacak (Serbia) over two-year period (2009–2011) on three cultivars (\u27Morens Jonagored\u27, \u27Gloster\u27 and \u27Granny Smith\u27). Fertigation included fertilizers NPK 16:8:32, NPK 12:0:43 and PGPR – inoculum of diazotrophic bacterium Klebsiella. Results of the study suggest that fertigation with 12:0:43 NPK fertilizer had the most pronounced effect on all generative potential parameters, except abundance of flowering (initial fruit set – 3.71; final fruit set – 3.31). Similarly, this fertilizer had the same effect on all yield parameters in the apple cultivars studied, i.e. yield per tree – 9.60 kg/tree, yield per unit land area – 24.40 t/ha, cumulative yield – 19.20 kg/tree, cumulative yield 48.00 t/ha and yield efficiency – 0.77 kg/cm2. Mineral fertilizer NPK 16:8:32 gave the highest abundance of flowering (4.51). In terms of pomological properties the applied fertilizers had a significant effect on fruit weight (239.05 g), soluble solids content (14.78%) and ripeness degree (4.75)

Uticaj biohemijskog sastava ploda na senzoričku ocenu kvaliteta ploda novointrodukovanih sorti jagode

The paper presents the results of the study conducted into the impact made by biochemical composition on sensory appraisal of the fruits of the ʻClery’, ʻJoly’ and ʻDely’ strawberry cultivars in the period 2012–2013. In 2012 a significantly higher content of total sugars was recorded in ʻDely’ and ʻClery’ cultivars, compared to ʻJoly’ cultivar. In 2013, a significantly higher content of total and reduced sugars were determined in the ʻJoly’ and ʻDely’ cultivar compared to ‘Clery’. Within the scope of the two years of research, the highest contents of sucrose was recorded in the ‘Joly’ strawberry cultivar. In the first trial year, the highest content of total acids was recorded in the ‘Clery’ cultivar, whereas in the second trial year the highest total acids content was found in the ‘Joly’ cultivar. A high cumulative grade for the sensory quality of fruit was attained by the ‘Joly’ cultivar, whereas the lowest cumulative grade was given to the ʻClery’ cultivar in both trial years. Considering the best score for the biochemical composition and sensory quality of the fruit, the ‘Joly’ cultivar can be recommended for more intensive use in the production practice.U radu su prikazani rezultati proučavanja uticaja biohemijskog sastava ploda na senzoričku ocenu kvaliteta ploda jagode sorti ʻClery’, ʻJoly’ i ʻDely’ u periodu 2012–2013. godina. Značajno viši sadržaj ukupnih šećera registrovan je kod sorti ʻDely’ i ʻClery’ u poređenju sa sortom ʻJoly’, u 2012. godini. U 2013. godini, značajno viši sadržaj ukupnih i invertnih šećera evidentiran je kod sorti ʻJoly’ i ʻDely’ u odnosu na sortu ‘Clery’. U dvogodišnjem periodu istraživanja, najveća vrednost sadržaja saharoze evidentirana je u plodu jagode sorte ʻJoly’. U prvoj godini istraživanja, najviši sadržaj ukupnih kiselina zabeležen je kod sorte ʻClery’, a u drugoj godini istraživanja kod sorte ʻJoly’. Visoke zbirne ocene za senzorički kvalitet ploda ostvarila je sorta ʻJoly’, a najniže zbirne ocene sorta ʻClery’, u obe godine istraživanja. Najbolje rezultate u pogledu biohemijskog sastava i senzoričkog kvaliteta ploda ostvarila je sorta ʻJoly’, pa se ova sorta može preporučiti za intenzivnije širenje u proizvodnoj praksi

Biološko-proizvodne osobine sorte jagode‘Leatitia’ na području Čačka

The paper presents results of the research of vegetative and generative potential, phenological properties and fruit quality of the promising strawberry cultivar ‘Leatitia’ in the 2016–2017 period. Significantly higher values of all tested parameters of vegetative, generative potential, productivity and fruit mass were determined in the second experimental year. High firmness values were determined in both years of the research, while significantly higher phenolics content and antioxidative capacity were registered in the fruits the second year after planting. Spread of the strawberry cultivar ‘Leatitia’ in production practices can be recommended primarily because of the late ripening, high productivity and very high quality of fruits.U radu su prikazani rezultati ispitivanja vegetativnog, generativnog potencijala, fenoloških osobina i kvaliteta ploda perspektivne sorte jagode ‘Leatitia’ u periodu 2016–2017. godine. U drugoj eksprimentalnoj godini, utvrđene su značajno više vrednosti svih ispitivanih parametara vegetativnog, generativnog potencijala, produktivnosti i mase ploda. Visoke vrednosti čvrstine ploda utvrđene su u obe godine istraživanja, dok su značajno veći fenolni sadržaj i antioksidativni kapacitet registrovani u plodovima jagode u drugoj godini nakon sadnje. Širenje sorte jagode ‘Leatitia’ u proizvodnjoj praksi može se preporučiti prevashodno zbog kasnog vremena zrenja, visoke rodnosti i veoma kvalitetnog ploda

Aberrations in Cytokine Signaling in Leukemia: Variations in Phosphorylation and O-GlcNAcylation

Tumor-induced immunosuppression can occur by multiple mechanisms, each posing a significant obstacle to immunotherapy. Evidence presented in this dissertation suggests that aberrant cytokine signaling, as a result of altered metabolism of Chronic Lymphocytic Leukemia (CLL) cells, confers a selective advantage for tumor survival and growth. Cells from CLL patients with aggressive disease (as indicated by high-risk cytogenetics) were found to exhibit prolongation in Interferon (IFN)-induced STAT3 phosphorylation, and increased levels of reactive oxygen species (ROS) in these cells reflected these signaling processes. Changes in the relative balance of phospho-STAT3 and phospho-STAT1 levels, in response to combinations of IL-2 + Toll-like receptor (TLR)-7 agonist + phorbol esters, as well as IFN, were associated with the immunosuppressive and immunogenic states of CLL cells. In addition, immunosuppressive leukemic cells were found to express high levels of proteins with O-linked N-acetylglucosamine (O-GlcNAc) modifications, due to increased metabolic activity through the Hexosamine Biosynthetic Pathway (HBP), which caused impaired intracellular signaling responses and affected disease progression. A conclusion of the studies presented here is that the intrinsic immunosuppressive properties of leukemic cells may be overcome by agents such as Resveratrol that target metabolic pathways of these cells.Ph