Experimental analysis of train slipstream in confined spaces

The train slipstream, i.e. the air velocities induced by the train, is one of the most important aerodynamic effects connected to railway vehicles because it has a direct impact on the safety of passengers on the platform and track workers along the railway line. In recent years, a lot of studies were performed to understand the development of this phenomenon in the open field and specific EU standards, the EN 14067-4 and the TSI (Technical Specifications for Interoperability) were issued. On the other hand, only few studies have been carried out to analyze the train passages in confined spaces (as tunnels, line sections with acoustic barriers, etc.), even if the first results of these analyses have shown that the confinement of the air causes more severe conditions regarding the speed of the air flow. This work aims at studying, through a full-scale experimental campaign, the effects of the flow confinement on the air speed caused by the train passage. In particular, the effects of different parameters, linked to the train i.e. the train type and length, the train speed and the measurement position, and linked to the infrastructure i.e. variations in the local infrastructure geometry, were analyzed

Full scale experimental tests to evaluate the train slipstream in tunnels

The train slipstream, i.e. the air velocity induced by the train, is one of the most important aerodynamic effects connected to railway vehicles because it has a direct impact on the safety of passengers on the platform and track workers along the railway line. In recent years, a lot of studies were performed to understand the development of this phenomenon in open field, and specific EU standards, the EN 14067–4 and the TSI were issued. Instead, only few studies have been carried out to analyse the train slipstream in confined spaces (as tunnels, line sections with acoustic barriers, etc.), even though the first results of these analyses have shown that the confinement of the air causes more severe conditions regarding the speed of the air flow. This work aims at studying, through a fullscale experimental campaign, the effects on the air flow speed caused by the train passage. The effects of different train parameters (i.e. train type and length, etc.) and infrastructure parameters (i.e. geometry variations) were analysed. Lastly, the results of a specific test considering the presence of a stationary train inside the tunnel while another train is passing are described, to simulate scenarios of ordinary railway traffic

A study of the influence of aerodynamic loads on the forces exchanged in a twistlock corner casting connection of flat-wagons

In this paper cross-wind effects on freight wagons are studied. A mathematical model of a freight train made up of a flat-car and one or two containers has been built defining the dynamical characteristics of the connection (twistlock-corner casting). Wind tunnel tests on a scaled model are then used to define the aerodynamic coefficients of the wagon, both in loaded and unloaded conditions, considering different trainset layouts. Wind forces are finally applied separately to the container and the flat-car in order to define the CWC of the wagon and to verify the maximum forces exchanged through the twistlock-corner casting connection. The results of the analysis showed that severe conditions with respect to the risk of rollover can be found as a result of a succession of empty and loaded wagons

High Field Studies of the Hidden Order Transition in URu2_2Si2_2

We studied in detail the low temperature/high magnetic field phases of URu$_{2}$Si$_{2}$ single crystals with specific heat, magnetocaloric effect, and magnetoresistance in magnetic fields up to 45 T. Data obtained down to 0.5 K, and extrapolated to T = 0, show a suppression of the hidden order phase at H$_{o}$(0) = 35.9 $\pm$ 0.35 T and the appearance of a new phase for magnetic fields in excess of H$_{1}$(0) = 36.1 $\pm$ 0.35 T observed \textit{only} at temperatures lower than 6 K. In turn, complete suppression of this high field state is attained at a critical magnetic field H$_{2}$(0) = 39.7 $\pm$ 0.35 T. No phase transitions are observed above 40 T. We discuss our results in the context of itinerant vs. localized \textit{f}-electron behavior and consider the implications for the hidden order phase.Comment: 4 pages, 3 figures Submitted May 10, 2002. Revised Sep 17, 200

In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as \u3b2-turn inducers

Small and easy-to-do mimetics of \u3b2-turns are of great interest to interfere with protein-protein recognition events mediated by \u3b2-turn recognition motifs. We propose a straightforward procedure for constraining the conformation of tetrapeptides lacking a pre-formed scaffold. According to the stereochemistry array, N-Ts tetrapeptides including Thr or PhSer (phenylserine) at the positions 2 or 3 gave rise in a single step to the sequences Oxd 2-Oxd3 or \u394Abu2-Oxd3 (Oxd, oxazolidin-2-one; \u394Abu, 2,3-dehydro-2-aminobutyric). These pseudo-Pro residues displayed highly constrained, and \u3c7 dihedral angles, and induced clear \u3b2-turns or inverse turns of type I or II, as determined by extensive spectroscopic and computational analyses. \ua9 The Royal Society of Chemistry 2013

Autonomic function in amnestic and non-amnestic mild cognitive impairment : spectral heart rate variability analysis provides evidence for a brain–heart axis

Mild cognitive impairment (MCI) is a heterogeneous syndrome with two main clinical subtypes, amnestic (aMCI) and non-amnestic (naMCI). The analysis of heart rate variability (HRV) is a tool to assess autonomic function. Cognitive and autonomic processes are linked via the central autonomic network. Autonomic dysfunction entails several adverse outcomes. However, very few studies have investigated autonomic function in MCI and none have considered MCI subtypes or the relationship of HRV indices with different cognitive domains and structural brain damage. We assessed autonomic function during an active orthostatic challenge in 253 oupatients aged\u2009 65\u200965, [n\u2009=\u200982 aMCI, n\u2009=\u200993 naMCI, n\u2009=\u200978 cognitively normal (CN), neuropsychologically tested] with power spectral analysis of HRV. We used visual rating scales to grade cerebrovascular burden and hippocampal/insular atrophy (HA/IA) on neuroimaging. Only aMCI showed a blunted response to orthostasis. Postural changes in normalised low frequency (LF) power and in the LF to high frequency ratio correlated with a memory test (positively) and HA/IA (negatively) in aMCI, and with attention/executive function tests (negatively) and cerebrovascular burden (positively) in naMCI. These results substantiate the view that the ANS is differentially impaired in aMCI and naMCI, consistently with the neuroanatomic substrate of Alzheimer's and small-vessel subcortical ischaemic disease

An interdisciplinary investigation of a recent submarine mass transport deposit at the continental margin off Uruguay

Assessing frequency and extent of mass movement at continental margins is crucial to evaluate risks for offshore constructions and coastal areas. A multidisciplinary approach including geophysical, sedimentological, geotechnical, and geochemical methods was applied to investigate multistage mass transport deposits (MTDs) off Uruguay, on top of which no surficial hemipelagic drape was detected based on echosounder data. Nonsteady state pore water conditions are evidenced by a distinct gradient change in the sulfate (SO42−) profile at 2.8 m depth. A sharp sedimentological contact at 2.43 m coincides with an abrupt downward increase in shear strength from ∼10 to >20 kPa. This boundary is interpreted as a paleosurface (and top of an older MTD) that has recently been covered by a sediment package during a younger landslide event. This youngest MTD supposedly originated from an upslope position and carried its initial pore water signature downward. The kink in the SO42− profile ∼35 cm below the sedimentological and geotechnical contact indicates that bioirrigation affected the paleosurface before deposition of the youngest MTD. Based on modeling of the diffusive re‐equilibration of SO42− the age of the most recent MTD is estimated to be <30 years. The mass movement was possibly related to an earthquake in 1988 (∼70 km southwest of the core location). Probabilistic slope stability back analysis of general landslide structures in the study area reveals that slope failure initiation requires additional ground accelerations. Therefore, we consider the earthquake as a reasonable trigger if additional weakening processes (e.g., erosion by previous retrogressive failure events or excess pore pressures) preconditioned the slope for failure. Our study reveals the necessity of multidisciplinary approaches to accurately recognize and date recent slope failures in complex settings such as the investigated area

SILICONE MIGRATION FROM RUPTURE BREAST IMPLANT. WHAT SHOULD BE DONE? REPORT OF THREE CASES AND REVIEW OF LITERATURE

Silicone implants are widely used in aesthetic and reconstructive breast surgery. Rupture of a breast implants is a well-known complication. Silicone leakage from a rupture or silicone bleeding can accumulate in lymphnodes because the silicone migrates through the lymphatics, and it can reach local or distant nodes. The systemic effects of silicone are unknow and object of debate. We report three cases of silicone migration from breast implants rupture in oncological patients. We aim to describe the correct diagnosis and treatment according to the date of the literatur