1,620 research outputs found
Coherent manipulation of electron spins up to ambient temperatures in Cr(S=1/2) doped KNbO
We report coherent spin manipulation on Cr (\emph{S} = 1/2, \emph{I} =
0) doped KNbO, which constitutes a dilute two-level model relevant for
use as a spin qubit. Rabi oscillations are observed for the first time in a
spin system based on transition metal oxides up to room temperature. At liquid
helium temperature the phase coherence relaxation time \emph{} reaches
s and, with a Rabi frequency of 20 MHz, yields a single qubit
figure of merit \emph{} of about 500. This shows that a diluted ensemble
of Cr (\emph{S} = 1/2) doped KNbO is a potential candidate for
solid-state quantum information processing.Comment: 4 page
A Large Atom Number Metastable Helium Bose-Einstein Condensate
We have produced a Bose-Einstein condensate of metastable helium (4He*)
containing over 1.5x10^7 atoms, which is a factor of 25 higher than previously
achieved. The improved starting conditions for evaporative cooling are obtained
by applying one-dimensional Doppler cooling inside a magnetic trap. The same
technique is successfully used to cool the spin-polarized fermionic isotope
(3He*), for which thermalizing collisions are highly suppressed. Our detection
techniques include absorption imaging, time-of-flight measurements on a
microchannel plate detector and ion counting to monitor the formation and decay
of the condensate.Comment: 4 pages, 3 figures (changed content
Global economic impacts of climate variability and change during the 20th century
Estimates of the global economic impacts of observed climate change during the 20th century obtained by applying five impact functions of different integrated assessment models (IAMs) are separated into their main natural and anthropogenic components. The estimates of the costs that can be attributed to natural variability factors and to the anthropogenic intervention with the climate system in general tend to show that: 1) during the first half of the century, the amplitude of the impacts associated with natural variability is considerably larger than that produced by anthropogenic factors and the effects of natural variability fluctuated between being negative and positive. These non-monotonic impacts are mostly determined by the low-frequency variability and the persistence of the climate system; 2) IAMs do not agree on the sign (nor on the magnitude) of the impacts of anthropogenic forcing but indicate that they steadily grew over the first part of the century, rapidly accelerated since the mid 1970's, and decelerated during the first decade of the 21st century. This deceleration is accentuated by the existence of interaction effects between natural variability and natural and anthropogenic forcing. The economic impacts of anthropogenic forcing range in the tenths of percentage of the world GDP by the end of the 20th century; 3) the impacts of natural forcing are about one order of magnitude lower than those associated with anthropogenic forcing and are dominated by the solar forcing; 4) the interaction effects between natural and anthropogenic factors can importantly modulate how impacts actually occur, at least for moderate increases in external forcing. Human activities became dominant drivers of the estimated economic impacts at the end of the 20th century, producing larger impacts than those of low-frequency natural variability. Some of the uses and limitations of IAMs are discussed
Fifteen years of NESDA Neuroimaging:An overview of results related to clinical profile and bio-social risk factors of major depressive disorder and common anxiety disorders
The longitudinal Netherlands Study of Depression and Anxiety (NESDA) Neuroimaging study was set up in 2003 to investigate whether neuroanatomical and functional abnormalities during tasks of primary emotional processing, executive planning and memory formation, and intrinsic brain connectivity are i) shared by individuals with major depressive disorder (MDD) and common anxiety disorders; and ii) characterized by symptomatologyspecific abnormalities. Furthermore, questions related to individual variations in vulnerability for onset, comorbidity, and longitudinal course could be investigated.& nbsp; Between 2005 and 2007, 233 individuals fulfilling a diagnosis of MDD, panic disorder, social anxiety disorder and/or generalized anxiety disorder and 68 healthy controls aging between 18 and 57 were invited from the NESDA main sample (n = 2981). An emotional faces processing task, an emotional word-encoding task, and an executive planning task were administered during 3T BOLD-fMRI acquisitions. In addition, resting state BOLDfMRI was acquired and T1-weighted structural imaging was performed. All participants were invited to participate in the two-year and nine-year follow-up MRI measurement.& nbsp; Fifteen years of NESDA Neuroimaging demonstrated common morphological and neurocognitive abnormalities across individuals with depression and anxiety disorders. It however provided limited support for the idea of more extensive abnormalities in patients suffering from both depression and anxiety, despite their worse prognosis. Risk factors including childhood maltreatment and specific risk genes had an emotion processing modulating effect, apparently stronger than effects of diagnostic labels. Furthermore, brain imaging data, especially during emotion processing seemed valuable for predicting the long-term course of affective disorders, outperforming prediction based on clinical information alone
Multiphoton coherent manipulation in large-spin qubits
Large spin Mn2+ ions (S=5/2) diluted in a non-magnetic MgO matrix of high
crystalline symmetry are used to realize a six level system that can be
operated by means of multi-photon coherent Rabi oscillations. This spin system
has a very small anisotropy which can be tuned in-situ to reversibly transform
the system between harmonic and non-harmonic level configurations. Decoherence
effects are strongly suppressed as a result of the quasi-isotropic electron
interaction with the crystal field and with the 55Mn nuclear spins. These
results suggest new ways of manipulating, reading and resetting spin quantum
states which can be applied to encode a qubit across several quantum levels.Comment: Published versio
Zinc Finger Artificial Transcription Factor-Mediated Chloroplast Genome Interrogation in Arabidopsis thaliana
The large majority of core photosynthesis proteins in plants are encoded by nuclear genes, but a small portion have been retained in the plastid genome. These plastid-encoded chloroplast proteins fulfill essential roles in the process of photochemistry. Here, we report the use of nuclear-encoded, chloroplast-targeted zinc finger artificial transcription factors (ZF-ATFs) with effector domains of prokaryotic origin to modulate the expression of chloroplast genes, and to enhance the photochemical activity and growth characteristics of Arabidopsis thaliana plants. This technique was named chloroplast genome interrogation. Using this novel approach, we obtained evidence that ZF-ATFs can indeed be translocated to chloroplasts of Arabidopsis plants, can modulate their growth and operating light use efficiency of PSII, and finally can induce statistically significant changes in the expression levels of several chloroplast genes. Our data suggest that the distortion of chloroplast gene expression might be a feasible approach to manipulate the efficiency of photosynthesis in plants
Mycobacterial type VII secretion systems
Mycobacteria, such as the pathogen M. tuberculosis, utilize up to five paralogous type VII secretion systems to transport proteins across their cell envelope. Since these proteins associate in pairs that depend on each other for transport to a different extent, the secretion pathway to the bacterial surface remained challenging to address. Structural characterization of the inner-membrane embedded secretion machineries along with recent advances on the substrates' co-dependencies for transport allow for the first time more detailed and testable models for secretion.Biophysical Structural Chemistr
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