Institutional arrangements for public debt management

This paper analyzes institutional arrangements for public debt management by reviewing the experience of OECD countries during the late 1980s and 1990s. It discusses principal-agent issues arising from the delegation of authority from the Minister of Finance to the debt management office and describes how countries have designed governance structures and control and monitoring mechanisms to deal with these issues. The paper also discusses what lessons emerging market countries and transition countries can draw from the experience of advanced OECD countries. The OECD experience clearly indicates that-regardless of whether the debt management office is located inside or outside the Ministry of Finance-four issues are of vital importance: 1) Giving priority to strategic public policy objectives rather than tactical trading objectives. 2) Strengthening the institutional capacity to deal with financial portfolio management and with the public policy aspects of debt management. 3) Modernizing debt management. 4) Creating mechanisms to ensure successful delegation and accountability to the Ministry of Finance and Parliament.Public Sector Economics&Finance,Public&Municipal Finance,Strategic Debt Management,Payment Systems&Infrastructure,Urban Economics,Public Sector Economics&Finance,Strategic Debt Management,Urban Economics,Public&Municipal Finance,Banks&Banking Reform

The effects of graded levels of calorie restriction : XX. impact of long term graded calorie restriction on survival and body mass dynamics in male C57BL/6J mice

The funding was raised by J.R.S. (Biotechnology and Biological Sciences Research Council, grant/award number: BB/G009953/1).Peer reviewedPublisher PD

The carbohydrate-insulin model does not explain the impact of varying dietary macronutrients on the body weight and adiposity of mice

Acknowledgments This study was funded by the Chinese Academy of Sciences Strategic Program (XDB13030100), the K.C. Wong Foundation, the 1000 Talents Program, and a Wolfson Merit Award to J.R.S. We thank those in the molecular energetics group in Beijing who contributed to handling the animals and the measurement of their food intake and body weight, including L. Li, B. Li, M. Li, G. Wang, X. Zhang, J. Li, C. Niu, E. Couper, A. Whittington-Davies, and M. Mazidi. Author contributions S.H. was involved in the initial experiment design, conducted experiment one, analyzed the data from experiments one and two, performed the IPA-related analysis, and co-wrote the manuscript. L.W. was involved in the sample collection for experiments one and two and conducted the RNA extractions and the RNA-seq. J.T. was involved in the sample and data collection for experiments one and two. D.Y. and Y.X. performed the initial data collection and glucose measurements for experiment two. Y.W. conducted the insulin measurements and was involved in the initial data collection for experiment two. A.D. was involved in the RNA-seq-related analysis. J.R.S. directed both projects, conceived and designed the experiments, contributed to the data analysis, and co-wrote the paper. All of the authors approved the final version prior to submission for publication.Peer reviewedPublisher PD

Impact of dietary sucrose on adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion : liquid or solid

The study was funded by the Chinese Academy of Sciences Strategic Program (XDB13030100), the 1000 Talents program, and the National Natural Science Foundation of China (91649108) and a Wolfson merit award from the Royal Society all to J.R.S.; J.T was supported by the CAS-TWAS president's fellowship.Peer reviewedPublisher PD

A single nucleotide mutation in the dual-oxidase 2 (DUOX2) gene causes some of the panda's unique metabolic phenotypes

This work was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDB13030100 and XDB29020000), the Creative Research Group Project of National Natural Science Foundation of China (31821001), the Key Project of the Chinese Academy of Sciences (QYZDB-SSW-SMC047), the National Key Research and Development Program of China (2018YFC2000500), the Chinese Academy of Sciences President's International Fellowship Initiative Postdoctoral Fellowship (to A.M.R.) and the President's International Fellowship Initiative Professorial and Wolfson Merit Award (to J.R.S.).Peer reviewedPublisher PD

Effects of dietary macronutrients and body composition on glucose homeostasis in mice

Funding This work was supported by the Chinese Academy of Sciences Strategic Programs (XDA12030209 and XDB13030100), the 1000 Talents Program and a Wolfson Merit Award to J.R.SPeer reviewedPublisher PD

The hedonic overdrive model best explains high-fat diet-induced obesity in C57BL/6 mice

Open Access via the Wiley Agreement National Key R&D Program of China. Grant Number: 2019YFA0801900 Chinese Academy of Sciences. Grant Number: XDB13030100 National Science Foundation of China. Grant Number: 92057206Peer reviewe

Effects of dietary macronutrients on the hepatic transcriptome and serum metabolome in mice

ACKNOWLEDGMENTS The study was funded by National Key R&D Program of China (2019YFA0801900), National Postdoctoral Program for Innovative Talents (BX2021357), Postdoctoral Science Foundation (2021M693393) the Chinese Academy of Sciences Strategic Program (XDB13030100), the National Natural Science Foundation of China (91649108), a PIFI professorial fellowship from CAS and a Wolfson merit award from the UK Royal Society (all to J.R.S unless stated).Peer reviewedPublisher PD

Dietary patterns of adults living in Ouagadougou and their association with overweight

<p>Abstract</p> <p>Background</p> <p>Urbanization in developing countries comes along with changes in food habits and living conditions and with an increase in overweight and associated health risks. The objective of the study was to describe dietary patterns of adults in Ouagadougou and to study their relationship with anthropometric status of the subjects.</p> <p>Methods</p> <p>A qualitative food frequency questionnaire was administered to 1,072 adults living in two contrasted districts of Ouagadougou. Dietary patterns were defined by principal component analysis and described by multivariate analysis. Logistic regression was used to study their association with overweight.</p> <p>Results</p> <p>The diet was mainly made of cereals, vegetables and fats from vegetable sources. The two first components of the principal component analysis were interpreted respectively as a "snacking" score and as a "modern foods" score. Both scores were positively and independently associated with the economic level of households and with food expenditures (p ≤ 0.001 for both). The "snacking" score was higher for younger people (p = 0.004), for people having a formal occupation (p = 0.006), for those never married (p = 0.005), whereas the "modern foods" score was associated with ethnic group (p = 0.032) and district of residence (p < 0.001). Thirty-six percent of women and 14.5% of men were overweight (Body Mass Index > 25 kg/m²). A higher "modern foods" score was associated with a higher prevalence of overweight when confounding factors were accounted for (OR = 1.19 [95% CI 1.03-1.36]) but there was no relationship between overweight and the "snacking" score.</p> <p>Conclusions</p> <p>Modernisation of types of foods consumed was associated with the living conditions and the environment and with an increased risk of overweight. This should be accounted for to promote better nutrition and prevent non communicable diseases.</p