A volumetric water budget of Devils Lake (USA): non-stationary precipitation–runoff relationships in an amplifier terminal lake

Devils Lake, a terminal lake in eastern North Dakota, rose more than 9 m between 1992 and 2013, producing a 286% increase in lake area, and causing more than US$1 billion in direct damages. An annual volumetric lake water budget is developed from monthly hydroclimatological variables for the period 1951–2010 to investigate the rapid lake expansion. The lake is an amplifier terminal lake in which long-term climatic changes are amplified by positive feedback mechanisms, causing the lake to transition from a precipitation-dominated to a runoff-dominated water budget. Factors specific to the Devils Lake Basin further amplify this positive feedback relationship. These include principles of fill–spill hydrology that operate between individual sub-basins within the closed basin, and between the innumerable wetland complexes within each sub-basin. These factors create a pronounced non-stationary precipitation–runoff relationship in the basin during both long-term wetting and drying phases

Mean hydroclimatic and hydrological conditions during two climatic modes in the Devils Lake Basin, North Dakota (USA)

Proxy variables from palaeolimnological studies of lakes in the Prairie Pothole Region of North America have been used to infer large oscillations during the late Holocene between longer periods of high-salinity–dry conditions and shorter periods of low-salinity–wet conditions producing a normative pattern marked by the absence of hydrological stability. Studies of the historical rise in lake level at Devils Lake have identified 1980 as a transition point between two such hydroclimatic modes. This study uses multiple datasets to characterize the mean hydroclimatological and hydrological conditions of these two climatic modes. Mode 1 is a cool and dry phase, and mode 2 is a warmer and wetter phase. Precipitation onto the lake increased by 24% from mode 1 to mode 2. This small, but sustained, increase produced significant changes in the mean hydroclimatic and hydrological states for the basin, including a 383% increase in surface run-off to the lake, and a 282% increase in the basin run-off ratio. Devils Lake Basin is located along a hydrotone (region of strong hydroclimatic gradients) where small changes in hydrological drivers are amplified into large changes in regional moisture. The effects of the fluctuating climatic modes and strong hydroclimatic gradients are probably further amplified by the unique fill–spill hydrology of the northern glaciated plains, which can result in nonlinear precipitation–run-off relationships. This natural pattern of extreme hydrological variations for Devils Lake produces enormous challenges for lake management

Geography: 1983-2007

This departmental history was written on the occasion of the UND Quasquicentennial in 2008.https://commons.und.edu/departmental-histories/1076/thumbnail.jp

Lake Flooding and Synoptic Weather-type Frequency At Devils Lake, North Dakota, USA, Between 1965 and 2010

Since the spring of 1993, the water surface elevation at Devils Lake, a terminal lake in eastern North Dakota, USA, has risen by 8.8 m, producing more than 1 billion USD in direct flood damages. We examine the relationship between weather-type frequencies at Bismarck, North Dakota, and lake volume changes from 1965 to 2010 using the Spatial Synoptic Classification (SSC) system. First, we find statistically significant changes in the frequency of selected weather types over both annual and seasonal time periods. This indicates a trend toward in - creased advection of more humid weather types that is consistent with the historical rise in lake level. Second, a comparison of weather type frequencies between a subset of years with extreme large and small lake surges, and extreme large and small lake drawdowns, shows that weathertype frequency plays an important role in explaining annual lake volume fluctuations. The results support a climatic explanation for the historical lake rise at Devils Lake, but the relationships are not as strong as might have been anticipated given the unprecedented lake rise that occurred during the study period. A more detailed examination of the complex and non-linear nature of the lake water balance may be needed to further clarify how precipitation input is translated into lake volume changes

Natural hydroclimatic forcing of historical lake volume fluctuations at Devils Lake, North Dakota (USA)

Devils Lake, a terminal saline lake in eastern North Dakota, has experienced catastrophic flooding over the past two decades producing direct damages in excess of $1 billion ($USD). We use three long-term datasets to examine the temporal coherence between historical lake fluctuations and basic hydroclimatic drivers. Monthly precipitation and mean monthly air temperature data are used to characterize long-term precipitation delivery and evaporative demand. Monthly water balance data for a representative location are used to assess basin soil moisture conditions. A lake volume time series documents lake volume fluctuation in response to long-term precipitation and regional soil moisture conditions. Three variables are derived from the datasets, each characterizing a different aspect of the region’s hydroclimatology. A rescaling technique is applied to each variable to examine the temporal coherence and relative patterns of the variables and to identify distinct homogeneous hydroclimatic regimes during the historical period. The three rescaled variables show strong temporal coherence and confirm 1980 as an abrupt transition year between two distinct long-term hydroclimatic modes. Mode 1, a longer and drier phase, runs from 1907 to 1980, while mode 2, a shorter and wetter phase, extends from 1981 to the present. Multi-decadal and century-scale fluctuations between these two modes are the key drivers of long-term lake volume fluctuations, upon which interannual- and interdecadal-scale climatic variability are superimposed. The similar rates of change among the rescaled variables provides evidence in support of the conclusion that long-term natural hydroclimatological variability is the primary driver of observed lake volume changes at Devils Lake during the Twentieth Century and provides a foundation upon which to evaluate the potential contributing effects of anthropogenic climate change, and human alterations of the land use hydrology

Probing the luminal microenvironment of reconstituted epithelial microtissues.

Polymeric microparticles can serve as carriers or sensors to instruct or characterize tissue biology. However, incorporating microparticles into tissues for in vitro assays remains a challenge. We exploit three-dimensional cell-patterning technologies and directed epithelial self-organization to deliver microparticles to the lumen of reconstituted human intestinal microtissues. We also develop a novel pH-sensitive microsensor that can measure the luminal pH of reconstituted epithelial microtissues. These studies offer a novel approach for investigating luminal microenvironments and drug-delivery across epithelial barriers

Snowpack control over the thermal offset of air and soil temperatures in eastern North Dakota

[1] The close relationship between air and ground temperatures has been used to reconstruct paleoclimate conditions from ground temperatures. Unfortunately, the presence of snow decouples air and ground temperatures and obscures their relationship. The objective of this paper is to investigate the role that snowpack conditions play in affecting the relationship between air and soil temperatures. The annual thermal offset between mean annual soil and air temperatures is examined over a 12 year period (1990–2002) at Fargo, ND, using observed soil temperatures along with simulations from a physically based snowpack model. Early season snow cover does not necessarily lead to large thermal offsets. These snowpacks, while low in density, also tended to be shallow and therefore do not provide much thermal insulation. Winter snowpacks explain a greater portion of the annual thermal offset. While denser than fall snowpacks, the extra depth and longer persistence leads to superior insulation of the ground

Drooling Reduction Intervention randomised trial (DRI): comparing the efficacy and acceptability of hyoscine patches and glycopyrronium liquid on drooling in children with neurodisability

Objective: Investigate whether hyoscine patch or glycopyrronium liquid is more effective and acceptable to treat drooling in children with neurodisability. Design: Multicentre, single-blind, randomised controlled trial. Setting: Recruitment through neurodisability teams; treatment by parents. Participants: Ninety children with neurodisability who had never received medication for drooling (55 boys, 35 girls; median age 4 years). Exclusion criteria: medication contraindicated; in a trial that could affect drooling or management. Intervention: Children were randomised to receive a hyoscine skin patch or glycopyrronium liquid. Dose was increased over 4 weeks to achieve optimum symptom control with minimal side-effects; steady dose then continued to 12 weeks. Primary and secondary outcomes: Primary outcome: Drooling Impact Scale (DIS) score at week-4. Secondary outcomes: change in DIS scores over 12 weeks, Drooling Severity and Frequency Scale and Treatment Satisfaction Questionnaire for Medication; adverse events; children’s perception about treatment. Results: Both medications yielded clinically and statistically significant reductions in mean DIS at week-4 (25.0 (SD 22.2) for hyoscine and 26.6 (SD 16) for glycopyrronium). There was no significant difference in change in DIS scores between treatment groups. By week-12, 26/47 (55%) children starting treatment were receiving hyoscine compared with 31/38 (82%) on glycopyrronium. There was a 42% increased chance of being on treatment at week-12 for children randomised to glycopyrronium relative to hyoscine (1.42, 95% CI 1.04 to 1.95). Conclusions: Hyoscine and glycopyrronium are clinically effective in treating drooling in children with neurodisability. Hyoscine produced more problematic side effects leading to a greater chance of treatment cessation

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity

Developing tissues contain motile populations of cells that can self-organize into spatially ordered tissues based on differences in their interfacial surface energies. However, it is unclear how self-organization by this mechanism remains robust when interfacial energies become heterogeneous in either time or space. The ducts and acini of the human mammary gland are prototypical heterogeneous and dynamic tissues comprising two concentrically arranged cell types. To investigate the consequences of cellular heterogeneity and plasticity on cell positioning in the mammary gland, we reconstituted its self-organization from aggregates of primary cells in vitro. We find that self-organization is dominated by the interfacial energy of the tissue–ECM boundary, rather than by differential homo- and heterotypic energies of cell–cell interaction. Surprisingly, interactions with the tissue–ECM boundary are binary, in that only one cell type interacts appreciably with the boundary. Using mathematical modeling and cell-type-specific knockdown of key regulators of cell–cell cohesion, we show that this strategy of self-organization is robust to severe perturbations affecting cell–cell contact formation. We also find that this mechanism of self-organization is conserved in the human prostate. Therefore, a binary interfacial interaction with the tissue boundary provides a flexible and generalizable strategy for forming and maintaining the structure of two-component tissues that exhibit abundant heterogeneity and plasticity. Our model also predicts that mutations affecting binary cell–ECM interactions are catastrophic and could contribute to loss of tissue architecture in diseases such as breast cancer