22 research outputs found

    Admissible evidence in the court of development evaluation? : the impact of CARE's SHOUHARDO Project on child stunting in Bangladesh

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    Along with the rise of the development effectiveness movement of the last few decades, experimental impact evaluation methods – randomised controlled trials and quasiexperimental techniques – have emerged as a dominant force. While the increased use of these methods has contributed to improved understanding of what works and whether specific projects have been successful, their ‘gold standard’ status threatens to exclude a large body of evidence from the development effectiveness dialogue. In this paper we conduct an evaluation of the impact on child stunting of CARE’s SHOUHARDO project in Bangladesh, the first large-scale project to use the rights-based, livelihoods approach to address malnutrition. In line with calls for a more balanced view of what constitutes rigor and scientific evidence, and for the use of more diversified and holistic methods in impact evaluations, we employ a mixed-methods approach. The results from multiple data sources and methods, including both non-experimental and quasi-experimental, are triangulated to arrive at the conclusions. We find that the project had an extraordinarily large impact on stunting among children 6–24 months old – on the order of a 4.5 percentage point reduction per year. We demonstrate that one reason the project reduced stunting by so much was because, consistent with the rights-based, livelihoods approach, it relied on both direct nutrition interventions and those that addressed underlying structural causes including poor sanitation, poverty, and deeply-entrenched inequalities in power between women and men. These findings have important policy implications given the slow progress in reducing malnutrition globally and that the widely-supported Scaling Up Nutrition initiative aimed at stepping up efforts to do so is in urgent need of guidance on how to integrate structural cause interventions with the direct nutrition interventions that are the initiative’s main focus. The evaluation also adds to the evidence that targeting the poor, rather than employing universal coverage, can help to accelerate reductions in child malnutrition. The paper concludes that, given the valuable policy lessons generated, the experience of the SHOUHARDO project merits solid standing in the knowledge bank of development effectiveness. More broadly, it illustrates how rigorous and informative evaluation of complex, multi-intervention projects can be undertaken even in the absence of the randomisation, nonproject control groups and/or panel data required by the experimental methods. Keywords: development effectiveness; impact evaluation; experimental methods; child malnutrition; Bangladesh

    Eradication of Metastatic Renal Cell Carcinoma after Adenovirus-Encoded TNF-Related Apoptosis-Inducing Ligand (TRAIL)/CpG Immunotherapy

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    Despite evidence that antitumor immunity can be protective against renal cell carcinoma (RCC), few patients respond objectively to immunotherapy and the disease is fatal once metastases develop. We asked to what extent combinatorial immunotherapy with Adenovirus-encoded murine TNF-related apoptosis-inducing ligand (Ad5mTRAIL) plus CpG oligonucleotide, given at the primary tumor site, would prove efficacious against metastatic murine RCC. To quantitate primary renal and metastatic tumor growth in mice, we developed a luciferase-expressing Renca cell line, and monitored tumor burdens via bioluminescent imaging. Orthotopic tumor challenge gave rise to aggressive primary tumors and lung metastases that were detectable by day 7. Intra-renal administration of Ad5mTRAIL+CpG on day 7 led to an influx of effector phenotype CD4 and CD8 T cells into the kidney by day 12 and regression of established primary renal tumors. Intra-renal immunotherapy also led to systemic immune responses characterized by splenomegaly, elevated serum IgG levels, increased CD4 and CD8 T cell infiltration into the lungs, and elimination of metastatic lung tumors. Tumor regression was primarily dependent upon CD8 T cells and resulted in prolonged survival of treated mice. Thus, local administration of Ad5mTRAIL+CpG at the primary tumor site can initiate CD8-dependent systemic immunity that is sufficient to cause regression of metastatic lung tumors. A similar approach may prove beneficial for patients with metastatic RCC

    How NGOs approach resilience programming

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    PRIFPRI1; 2020; CRP2; CRP4; E Building Resilience; G Cross-cutting gender themeDGO; PIM; A4NHCGIAR Research Program on Policies, Institutions, and Markets (PIM); CGIAR Research Program on Agriculture for Nutrition and Health (A4NH

    The regional network on AIDS, livelihoods, and food security (RENEWAL): Influencing change in HIV/AIDS policy through networks

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    As the magnitude and scope of the AIDS epidemic grew during the 1990s, it transformed the international development landscape: HIV/AIDS became a global development issue with socioeconomic implications for livelihoods, rather than an isolated health issue. Sub-Saharan Africa remains the most HIV-affected region in the world: an estimated 22.4 million people live with HIV in Sub-Saharan Africa. In response to this crisis, the Regional Network on AIDS, Livelihoods, and Food Security (RENEWAL) was officially launched in 2001 as a joint project of the International Food Policy Research Institute (IFPRI) and the International Service for National Agricultural Research (ISNAR), and was operational in Malawi, Uganda, Kenya, Zambia, and South Africa through most of 2011.Non-PRIFPRI1; RENEWAL; IADG

    Building resilience for food and nutrition security, Addis Ababa, 15–17 of May 2014: A synthesis

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    PRIFPRI3; ISI; 2020DG

    Ex-post impact assessment review of the Regional Network on AIDS, Livelihoods, and Food Security (RENEWAL)

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    This report assesses the impact of RENEWAL activities from 2000 to 2010 and is based on a review of products resulting from RENEWAL activities (such as books, policy briefs, workshop summaries, reports, and discussion papers), stakeholder perceptions of RENEWAL products and activities, and national policy or programming changes resulting from RENEWAL-supported action research, capacity strengthening efforts, and policy communications.PRIFPRI1; RENEWAL; IADG

    Current approaches to resilience programming among nongovernmental organizations

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    This paper seeks to enhance our understanding of resilience processes, activities, and outcomes by examining initiatives to enhance resilience capacity that are designed and implemented by nongovernmental organizations (NGOs). The paper begins with a review of the evolution in thinking about the concept of resilience that has occurred over the past five years. This is followed by a review of the wide range of strategies and interventions employed by NGOs to build resilience capacity. The paper then presents several case studies that highlight NGO efforts to enhance resilience either by focusing on a specific vulnerable population and shock or by integrating, sequencing, and layering activities to support and protect core programming goals (for example, food and nutrition security, poverty reduction) while contributing overall to enhanced resilience capacity. Finally, the paper reviews measurement issues related to resilience, the challenges encountered by NGOs, and lessons learned. The paper concludes with a number of recommendations for improving NGO resilience programming.PRIFPRI1; E Building Resilience; E.1 Policies, institutions and investments for resilient social systems; 2020; CRP2; CRP4DGO; A4NH; PIMCGIAR Research Program on Policies, Institutions, and Markets (PIM); CGIAR Research Program on Agriculture for Nutrition and Health (A4NH

    Resilience programming among nongovernmental organizations: Lessons for policymakers

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    This food policy report reviews resilience processes, activities, and outcomes by examining a number of case studies of initiatives by nongovernmental organizations (NGOs) to enhance resilience capacity, and draws implications for policymakers and other stakeholders looking to strengthen resilience.Tables and Figures iv Executive Summary v A Shift in Policy Debate 1 A Framework for Understanding Resilience 2 Programming 5 Opportunities 24 Conclusions/Recommendations 29 Notes 31 References 32 About the Authors 37PRIFPRI1; CRP2; CRP4; 2020; E Building ResilienceDGO; A4NH; PIMCGIAR Research Program on Policies, Institutions, and Markets (PIM); CGIAR Research Program on Agriculture for Nutrition and Health (A4NH

    Nongovernmental organizations’ approaches to resilience programming

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    PRIFPRI1; CRP4; CRP2; 2020; E Building Resilience; E.1 Policies, institutions and investments for resilient social systemsDGO; PIM; A4NHCGIAR Research Program on Policies, Institutions, and Markets (PIM); CGIAR Research Program on Agriculture for Nutrition and Health (A4NH
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