Principal-Agent Relationships in Agricultural Cooperatives: An Empirical Analysis from Rural Alberta

Cooperatives throughout North America are consolidating at an increasing rate and for a variety of reasons. While many cooperatives merge with others or are acquired to achieve greater economies of scale, several fail due to changes in the external economy, which make them redundant. Often, such redundancy is reflected in a heightened sense of member dissatisfaction. Many argue that such dissatisfaction is likely to arise in cooperatives as a result of principal-agent problems. In order to determine whether or not cooperative managers maintain the same goals as their owners, this study uses data from a member-survey to compare Alberta cooperative members' objectives with those they believe to be held by their cooperatives' managers. An econometric model of the difference between members' expectations and perceptions shows how various socioeconomic variables affect the extent to which these objectives are aligned. The results of this analysis can help cooperative boards design managerial incentive programs to better align their goals with those of the cooperative membership.Agribusiness,

A Decade of Veteran Voices: Examining Patient Portal Enhancements Through the Lens of User-Centered Design

BACKGROUND: Health care systems have entered a new era focused on patient engagement. Patient portals linked to electronic health records are recognized as a promising multifaceted tool to help achieve patient engagement goals. Achieving significant growth in adoption and use requires agile evaluation methods to complement periodic formal research efforts. OBJECTIVE: This paper describes one of the implementation strategies that the Department of Veterans Affairs (VA) has used to foster the adoption and sustained use of its patient portal, My HealtheVet, over the last decade: an ongoing focus on user-centered design (UCD). This strategy entails understanding the users and their tasks and goals and optimizing portal design and functionality accordingly. Using a case study approach, we present a comparison of early user demographics and preferences with more recent data and several examples to illustrate how a UCD can serve as an effective implementation strategy for a patient portal within a large integrated health care system. METHODS: VA has employed a customer experience analytics (CXA) survey on its patient portal since 2007 to enable ongoing direct user feedback. In a continuous cycle, a random sample of site visitors is invited to participate in the Web-based survey. CXA model questions are used to track and trend satisfaction, while custom questions collect data about users\u27 characteristics, needs, and preferences. In this case study, we performed analyses of descriptive statistics comparing user characteristics and preferences from FY2008 (wherein FY means fiscal year ) to FY2017 and user trends regarding satisfaction with and utilization of specific portal functions over the last decade, as well as qualitative content analysis of user\u27s open-ended survey comments. RESULTS: User feedback has guided the development of enhancements to core components of the My HealtheVet portal including available features, content, interface design, prospective functional design, and related policies. Ten-year data regarding user characteristics and portal utilization demonstrate trends toward greater patient engagement and satisfaction. Administration of a continuous voluntary Web-based survey is an efficient and effective way to capture veterans\u27 voices about who they are, how they use the patient portal, needed system improvements, and desired additional services. CONCLUSIONS: Leveraging voice-of-the-customer techniques as part of patient portal implementation can ensure that such systems meet users\u27 needs in ways that are agile and most effective. Through this strategy, VA has fostered significant adoption and use of My HealtheVet to engage patients in managing their health

Evaluation of three lidar scanning strategies for turbulence measurements

Several errors occur when a traditional Doppler beam swinging (DBS) or velocity–azimuth display (VAD) strategy is used to measure turbulence with a lidar. To mitigate some of these errors, a scanning strategy was recently developed which employs six beam positions to independently estimate the <i>u</i>, <i>v</i>, and <i>w</i> velocity variances and covariances. In order to assess the ability of these different scanning techniques to measure turbulence, a Halo scanning lidar, WindCube v2 pulsed lidar, and ZephIR continuous wave lidar were deployed at field sites in Oklahoma and Colorado with collocated sonic anemometers.</br></br>Results indicate that the six-beam strategy mitigates some of the errors caused by VAD and DBS scans, but the strategy is strongly affected by errors in the variance measured at the different beam positions. The ZephIR and WindCube lidars overestimated horizontal variance values by over 60 % under unstable conditions as a result of variance contamination, where additional variance components contaminate the true value of the variance. A correction method was developed for the WindCube lidar that uses variance calculated from the vertical beam position to reduce variance contamination in the <i>u</i> and <i>v</i> variance components. The correction method reduced WindCube variance estimates by over 20 % at both the Oklahoma and Colorado sites under unstable conditions, when variance contamination is largest. This correction method can be easily applied to other lidars that contain a vertical beam position and is a promising method for accurately estimating turbulence with commercially available lidars

Discrimination Reversal Learning in Capuchin Monkeys (Cebus apella)

Learning styles in capuchin monkeys were assessed with a computerized reversal- learning task called the mediationaJ paradigm. First, monkeys were trained to respond with 90% accuracy on a two-choice discrimination (A+B-). Then the authors examined differences in performance on three different types of reversal trials (A-B+, A-C+, B+C-), each of which offered differing predictions for performance, depending on whether the monkeys were using associative cues or rule-based strategies. Performance indicated that the monkeys mainly learned to avoid the B stimulus during training, as the A-C+ condition produced the best performance levels. Therefore, negative stimuli showed greater control over responding after reversal and reflected a more associative rather than rule-based form of learning

Identification of Modifier Genes in a Mouse Model of Gaucher Disease.

Diseases caused by single-gene mutations can display substantial phenotypic variability, which may be due to genetic, environmental, or epigenetic modifiers. Here, we induce Gaucher disease (GD), a rare inherited metabolic disorder, by injecting 15 inbred mouse strains with a low dose of a chemical inhibitor of acid β-glucosidase, the enzyme defective in GD. Different mouse strains exhibit widely different lifespans, which is unrelated to levels of acid β-glucosidase's substrate accumulation. Genome-wide association reveals a number of candidate risk loci, including a marker within Grin2b, which in combination with another marker allows us to predict the lifespan of additional mouse strains. An antagonist of the NMDA receptor (encoded by Grin2b) significantly increases the lifespan of GD mice that would otherwise have lived for a short time. Our data identify putative modifier genes that may be involved in determining GD severity, which might help elucidate phenotypic variability between patients with similar GD mutations.Children’s Gaucher Research Fund, Pfizer, Minerva Foundation, National Institutes of Health (Grant ID: GM076217), Medical Research Council (Grant ID: MR/K015338/1), Cambridge Biomedical Research Centre of National Institute for Health Research, UK Gaucher Association, Rosetrees Trust, Weizmann Institute of ScienceThis is the final version of the article. It first appeared from Elsevier (Cell Press) via http://dx.doi.org/10.1016/j.celrep.2016.07.08

The Magnetic Field of the Irregular Galaxy NGC 4214

We examine the magnetic field in NGC 4214, a nearby irregular galaxy, using multi-wavelength radio continuum polarization data from the Very Large Array. We find that the global radio continuum spectrum shows signs that free-free absorption and/or synchrotron losses may be important. The 3cm radio continuum morphology is similar to that of the Halpha, while the 20cm emission is more diffuse. We estimate that 50% of the radio continuum emission in the center of the galaxy is thermal. Our estimate of the magnetic field strength is $30\pm 9.5$ \uG\ in the center and $10\pm3$ \uG\ at the edges. We find that the hot gas, magnetic, and the gravitational pressures are all the same order of magnitude. Inside the central star forming regions, we find that the thermal and turbulent pressures of the HII regions dominate the pressure balance. We do not detect any significant polarization on size scales greater than 200 pc. We place an upper limit of 8 \uG\ on the uniform field strength in this galaxy. We suggest that the diffuse synchrotron region, seen to the north of the main body of emission at 20cm, is elongated due to a uniform magnetic field with a maximum field strength of 7.6 \uG. We find that, while the shear in NGC 4214 is comparable to that of the Milky Way, the supernova rate is half that of the Milky Way and suggest that the star formation episode in NGC 4214 needs additional time to build up enough turbulence to drive an $\alpha-\omega$ dynamo.Comment: Accepted by ApJ. Version with high resolution figures at http://www.astro.virginia.edu/~aak8t/data/n4214/ms.pd

Life-Expectancy Disparities Among Adults With HIV in the United States and Canada: The Impact of a Reduction in Drug- and Alcohol-Related Deaths Using the Lives Saved Simulation Model.

Improvements in life expectancy among people living with human immunodeficiency virus (PLWH) receiving antiretroviral treatment in the United States and Canada might differ among key populations. Given the difference in substance use among key populations and the current opioid epidemic, drug- and alcohol-related deaths might be contributing to the disparities in life expectancy. We sought to estimate life expectancy at age 20 years in key populations (and their comparison groups) in 3 time periods (2004-2007, 2008-2011, and 2012-2015) and the potential increase in expected life expectancy with a simulated 20% reduction in drug- and alcohol-related deaths using the novel Lives Saved Simulation model. Among 92,289 PLWH, life expectancy increased in all key populations and comparison groups from 2004-2007 to 2012-2015. Disparities in survival of approximately a decade persisted among black versus white men who have sex with men and people with (vs. without) a history of injection drug use. A 20% reduction in drug- and alcohol-related mortality would have the greatest life-expectancy benefit for black men who have sex with men, white women, and people with a history of injection drug use. Our findings suggest that preventing drug- and alcohol-related deaths among PLWH could narrow disparities in life expectancy among some key populations, but other causes of death must be addressed to further narrow the disparities

The mysteries of mammatus clouds: Observations and formation mechanisms

Mammatus clouds are an intriguing enigma of atmospheric fluid dynamics and cloud physics. Most commonly observed on the underside of cumulonimbus anvils, mammatus also occur on the underside of cirrus, cirrocumulus, altocumulus, altostratus, and stratocumulus, as well as in contrails from jet aircraft and pyrocumulus ash clouds from volcanic eruptions. Despite their aesthetic appearance, mammatus have been the subject of few quantitative research studies. Observations of mammatus have been obtained largely through serendipitous opportunities with a single observing system (e.g., aircraft penetrations, visual observations, lidar, radar) or tangential observations from field programs with other objectives. Theories describing mammatus remain untested, as adequate measurements for validation do not exist because of the small distance scales and short time scales of mammatus. Modeling studies of mammatus are virtually nonexistent. As a result, relatively little is known about the environment, formation mechanisms, properties, microphysics, and dynamics of mammatus. This paper presents a review of mammatus clouds that addresses these mysteries. Previous observations of mammatus and proposed formation mechanisms are discussed. These hypothesized mechanisms are anvil subsidence, subcloud evaporation/sublimation, melting, hydrometeor fallout, cloud-base detrainment instability, radiative effects, gravity waves, Kelvin-Helmholtz instability, Rayleigh-Taylor instability, and Rayleigh-Bénard-like convection. Other issues addressed in this paper include whether mammatus are composed of ice or liquid water hydrometeors, why mammatus are smooth, what controls the temporal and spatial scales and organization of individual mammatus lobes, and what are the properties of volcanic ash clouds that produce mammatus? The similarities and differences between mammatus, virga, stalactites, and reticular clouds are also discussed. Finally, because much still remains to be learned, research opportunities are described for using mammatus as a window into the microphysical, turbulent, and dynamical processes occurring on the underside of clouds. © 2006 American Meteorological Society

Joint Statement on Pediatric Education at Schools of Pharmacy

Providing health care for children is a unique specialty, and pediatric patients represent approximately 25% of the population. Education of pharmacy students on patients across the lifespan is required by current Accreditation Council for Pharmacy Education standards and outcomes; thus, it is essential that pharmacy students gain a proficiency in caring for children. A collaborative panel of pediatric faculty members from schools and colleges of pharmacy was established to review the current literature regarding pediatric education in Doctor of Pharmacy curricula and establish updated recommendations for the provision of pediatric pharmacy education. This statement outlines five recommendations supporting inclusion of pediatric content and skills in Doctor of Pharmacy curricula