A theatrical life : negotiating biracial identity

My paintings and drawings use autobiography, fiction, and theatricality to examine biracial-identity formation and the negotiation of different cultural ideologies. The personification of these ideologies in narrative accounts pose questions to which the characters must answer and respond. This leads to humorous, sad, problematic, empowering, and chaotic compositions that become an intimate chronicle of my own endeavor to find those “perfect” answers. In my practice, painting and drawing are ways to explore a broad range of topics that stem from personal and familial stories. Using allegorical personifications, symbols, and metaphors derived from my family, I see the home as a stage for these characters to live out their lives. Here, the characters are faced with different circumstances and have to navigate them. The protagonist of these works is the two-headed man/conjoined twin. Based on myself, this character embodies opposing ideologies and is in a constant state of negotiation with himself

Central Serous Chorioretinopathy after Solar Eclipse Viewing

Purpose: To report a case of central serous chorioretinopathy after solar eclipse viewing. Case Report: A middle-age man developed a sudden-onset unilateral scotoma after viewing a partial solar eclipse in Hong Kong. Fundus examination, fluorescein angiography, and optical coherence tomography showed features compatible with central serous chorioretinopathy. The patient was managed conservatively and reevaluated periodically. Serial optical coherence tomographic evaluations demonstrated an initial increase in the amount of subretinal fluid which spontaneously resolved 10 weeks after the onset of symptoms. Conclusion: This case demonstrates the possibility of development of central serous chorioretinopathy following solar eclipse viewing

Human-Powered Swing Generator

Many developing countries lack sufficient resources to provide enough electricity for every family to live with a satisfying level of comfort and convenience. Our project proposes a solution that provides families with an alternative access to electricity using a playground swing. This project addresses the design and construction of the Human-Powered Swing Generator, which converts mechanical energy to electrical energy for charging a battery. The charged battery serves as a source of DC energy for potential DC purposes, such as charging a cell phone

Communicating Socially Acceptable Risk Judgments: The Role of Impression Information Insufficiency in The Risk Information Seeking and Processing Model

The COVID-19 pandemic has created uncertainty and controversy around risk-related issues such as vaccine mandates. People expressing their opinions on these issues to important others, such as employers, may face significant consequences, such as rewards or rejection. Therefore, people may try to find, avoid, or use information in a way that helps them express risk judgments that are socially acceptable in different social situations. This study investigated how people seek, avoid, and process risk information when they are concerned about their impression management. It also introduced the concept of impression information insufficiency (the perceived gap between the information one has and the information one needs to convey socially acceptable judgments and meet interpersonal needs in social situations) and examined its antecedents and outcomes within the risk information seeking and processing model. We conducted an online survey with 1673 Hong Kong adults during the COVID-19 pandemic. The results showed that fear and social norms related to greater impression information insufficiency, which thereby was associated with biased risk information seeking, avoidance, and processing

Long-Term Follow-Up of Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization due to Choroidal Osteoma

Choroidal osteoma is an uncommon benign osseous intraocular tumor that typically affects young adult women. Choroidal neovascularization (CNV) is one of the complications that can develop in eyes with choroidal osteoma. We present a case of CNV secondary to choroidal osteoma treated with intravitreal ranibizumab. A 57-year-old lady presented with painless loss of vision with a right-eye visual acuity of 20/800. Fundus examination showed a well-demarcated yellowish peripapillary choroidal osteoma with associated retinal and subretinal hemorrhage due to CNV. Three intravitreal ranibizumab injections at monthly intervals were given and her visual acuity improved to 20/30 following treatment. After 1.2 years of follow-up, the right eye visual acuity was maintained at 20/30 with no evidence of CNV recurrence. Our findings suggest that intravitreal ranibizumab may be an effective therapeutic option for treating CNV secondary to choroidal osteoma

Probing the A1 to L10 Transformation in FeCuPt Using the First Order Reversal Curve Method

The A1- L10 phase transformation has been investigated in (001) FeCuPt thin films prepared by atomic-scale multilayer sputtering and rapid thermal annealing (RTA). Traditional x-ray diffraction is not always applicable in generating a true order parameter, due to non-ideal crystallinity of the A1 phase. Using the first-order reversal curve (FORC) method, the A1 and L10 phases are deconvoluted into two distinct features in the FORC distribution, whose relative intensities change with the RTA temperature. The L10 ordering takes place via a nucleation-and-growth mode. A magnetization-based phase fraction is extracted, providing a quantitative measure of the L10 phase homogeneity.Comment: 17 pages, 5 figures, 4 page supplementary material (4 figures

In Silico Enhanced Restriction Enzyme Based Methylation Analysis of the Human Glioblastoma Genome Using Agilent 244K CpG Island Microarrays

Genome wide methylation profiling of gliomas is likely to provide important clues to improving treatment outcomes. Restriction enzyme based approaches have been widely utilized for methylation profiling of cancer genomes and will continue to have importance in combination with higher density microarrays. With the availability of the human genome sequence and microarray probe sequences, these approaches can be readily characterized and optimized via in silico modeling. We adapted the previously described HpaII/MspI based Methylation Sensitive Restriction Enzyme (MSRE) assay for use with two-color Agilent 244K CpG island microarrays. In this assay, fragmented genomic DNA is digested in separate reactions with isoschizomeric HpaII (methylation-sensitive) and MspI (methylation-insensitive) restriction enzymes. Using in silico hybridization, we found that genomic fragmentation with BfaI was superior to MseI, providing a maximum effective coverage of 22,362 CpG islands in the human genome. In addition, we confirmed the presence of an internal control group of fragments lacking HpaII/MspI sites which enable separation of methylated and unmethylated fragments. We used this method on genomic DNA isolated from normal brain, U87MG cells, and a glioblastoma patient tumor sample and confirmed selected differentially methylated CpG islands using bisulfite sequencing. Along with additional validation points, we performed a receiver operating characteristics (ROC) analysis to determine the optimal threshold (p ≤ 0.001). Based on this threshold, we identified ∼2,400 CpG islands common to all three samples and 145 CpG islands unique to glioblastoma. These data provide general guidance to individuals seeking to maximize effective coverage using restriction enzyme based methylation profiling approaches

Diffusion MR Characteristics Following Concurrent Radiochemotherapy Predicts Progression-Free and Overall Survival in Newly Diagnosed Glioblastoma.

The standard of care for newly diagnosed glioblastoma (GBM) is surgery, then radiotherapy (RT) with concurrent temozolomide (TMZ), followed by adjuvant TMZ. We hypothesized patients with low diffusivity measured using apparent diffusion coefficient (ADC) histogram analysis evaluated after RT+TMZ, prior to adjuvant TMZ, would have a significantly shorter progression-free (PFS) and overall survival (OS). To test this hypothesis we evaluated 120 patients with newly diagnosed GBM receiving RT+TMZ followed by adjuvant TMZ. MRI was performed after completion of RT+TMZ, prior to initiation of adjuvant TMZ. A double Gaussian mixed model was used to describe the ADC histograms within the enhancing tumor, where ADCL and ADCH were defined as the mean ADC value of the lower and higher Gaussian distribution, respectively. An ADCL value of 1.0 um2/ms and ADCH value of 1.6 um2/ms were used to stratify patients into high and low risk categories. Results suggest patients with low ADCL had significantly shorter PFS (Cox Hazard Ratio = 0.12, P = 0.0006). OS was significantly shorter with low ADCL tumors, showing a median OS of 407 vs. 644 days (Cox Hazard Ratio = 0.31, P = 0.047). ADCH was not predictive of PFS or OS when accounting for age and ADCL. In summary, newly diagnosed glioblastoma patients with low ADCL after completion of RT+TMZ are likely to progress and die earlier than patients with higher ADCL. Results suggest ADC histogram analysis may be useful for patient risk stratification following completion of RT+TMZ

Discerning Exoplanet Migration Models Using Spin-Orbit Measurements

We investigate the current sample of exoplanet spin-orbit measurements to determine whether a dominant planet migration channel can be identified, and at what confidence. We use the predictions of Kozai migration plus tidal friction (Fabrycky and Tremaine 2007) and planet-planet scattering (Nagasawa et al. 2008) as our misalignment models, and we allow for a fraction of intrinsically aligned systems, explainable by disk migration. Bayesian model comparison demonstrates that the current sample of 32 spin-orbit measurements strongly favors a two-mode migration scenario combining planet-planet scattering and disk migration over a single-mode Kozai migration scenario. Our analysis indicates that between 34% and 76% of close-in planets (95% confidence) migrated via planet-planet scattering. Separately analyzing the subsample of 12 stars with T_eff > 6250 K---which Winn et al. (2010) predict to be the only type of stars to maintain their primordial misalignments---we find that the data favor a single-mode scattering model over Kozai with 81% confidence. We also assess the number of additional hot star spin-orbit measurements that will likely be necessary to provide a more confident model selection, finding that an additional 20-30 measurements has a >50% chance of resulting in a 95%-confident model selection, if the current model selection is correct. While we test only the predictions of particular Kozai and scattering migration models in this work, our methods may be used to test the predictions of any other spin-orbit misaligning mechanism.Comment: 9 pages, 8 figures, ApJ responded to refere