PRESSOR EFFECT OF THE BARORECEPTOR REFLEX, DEPRESSOR EFFECT OF SEPTAL STIMULATION AND THEIR INTERACTIONS

65210111

The relevance of patient individuality in the evaluation and treatment of aphasia - Case report

The usual approach to language disorders relies on standardised evaluations in which pattern-tests characterise the subject's status according to the classical aphasiological typology. Those data are then analysed to support a traditional prevalent criterion for the distinction between ''normal'' and ''pathological'' linguistic performance, which is strictly focused on a quantitative approach. In the present study a method for evaluation and treatment of aphasia is proposed in which socio-cultural conditions are emphasised, in order to expand this conventional criterion as to encompass a qualitative (individualised) one. Although the methodology draws the attention, the results here obtained also point to the importance of re-evaluating what is presently considered as the most appropriate criterion for ''normal'' cognitive processes, particularly those related to language.553B65065

NEURAL MECHANISMS INVOLVED in the RECOVERY FROM INSULIN HYPOGLYCEMIA in DOGS

NIMH,CEREBRAL METAB LAB,BETHESDA,MD 20205UNIV São Paulo,INST BIOMED SCI,DEPT PHYSIOL & PHARMACOL,BR-05508 São Paulo,SP,BRAZILEscola Paulista de MedicinaWeb of Scienc

TIME COURSE of INSULIN, CORTICOSTERONE and METABOLIC CHANGES CAUSED BY LESION of the VENTROMEDIAL HYPOTHALAMUS in the RAT

ESCOLA PAULISTA MED,DEPT PHYSIOL,DIV NEUROPHYSIOL & ENDOCRINE PHYSIOL,BR-04023 São Paulo,SP,BRAZILESCOLA PAULISTA MED,DEPT PHYSIOL,DIV NEUROPHYSIOL & ENDOCRINE PHYSIOL,BR-04023 São Paulo,SP,BRAZILWeb of Scienc

Effect of chemical stimulation of the dorsomedial hypothalamic nucleus on blood plasma glucose, triglycerides and free fatty acids in rats

The effects of chemical stimulation of the dorsomedial hypothalamic nucleus (DMH) on blood plasma concentration of glucose, triglycerides, insulin, and free fatty acids (FFA) were investigated in anesthetized adult Wistar rats. Microinjection of 12.5 nmol of norepinephrine into the DMH increased blood plasma concentration of glucose and FFA, decreased triglycerides, and did not change plasma insulin within 5 min; after 20 min, blood glucose and FFA reached control values. Microinjection of epinephrine (12.5 nmol) into the DMH also increased blood plasma glucose concentration and decreased triglycerides after 5 min. These effects are probably mediated by beta-adrenergic mechanisms, because they were prevented by beta-adrenergic antagonist propranolol, but not by alpha-adrenergic antagonist prazosin. Microinjection into the DMH of glutamate, dopamine, or acetylcholine failed to cause any change in those metabolic parameters, corroborating the hypothesis that the DMH is part of a beta-adrenergic pathway involved in short-term modulation of the availability of glucose and FFA. Copyright (C) 1997 Elsevier Science Inc.UNIV ESTADUAL LONDRINA,DEPT QUIM,BR-86051 LONDRINA,PR,BRAZILUNIV ESTADUAL CAMPINAS,DEPT PHYSIOL,BR-13081970 CAMPINAS,SP,BRAZILUniversidade Federal de São Paulo,DEPT FISIOL,São Paulo,BRAZILUNIV São Paulo,FAC MED,BR-05508 São Paulo,BRAZILUniversidade Federal de São Paulo,DEPT FISIOL,São Paulo,BRAZILWeb of Scienc

Effect of chemical stimulation of the dorsomedial hypothalamic nucleus on blood plasma glucose, triglycerides and free fatty acids in rats

The effects of chemical stimulation of the dorsomedial hypothalamic nucleus (DMH) on blood plasma concentration of glucose, triglycerides, insulin, and free fatty acids (FFA) were investigated in anesthetized adult Wistar rats. Microinjection of 12.5 nmol of norepinephrine into the DMH increased blood plasma concentration of glucose and FFA, decreased triglycerides, and did not change plasma insulin within 5 min; after 20 min, blood glucose and FFA reached control values. Microinjection of epinephrine (12.5 nmol) into the DMH also increased blood plasma glucose concentration and decreased triglycerides after 5 min. These effects are probably mediated by beta-adrenergic mechanisms, because they were prevented by beta-adrenergic antagonist propranolol, but not by alpha-adrenergic antagonist prazosin. Microinjection into the DMH of glutamate, dopamine, or acetylcholine failed to cause any change in those metabolic parameters, corroborating the hypothesis that the DMH is part of a beta-adrenergic pathway involved in short-term modulation of the availability of glucose and FFA. Copyright (C) 1997 Elsevier Science Inc.42319519