The Status of the Pion-Nucleon Coupling Constant

A review is given of the various determinations of the different piNN coupling constants in analyses of the low-energy pp, np, pbarp, and pi-p scattering data. The most accurate determinations are in the energy-dependent partial-wave analyses of the NN data. The recommended value is f^2 = 0.075 . A recent determination of f^2 by the Uppsala group from backward np cross sections is shown to be model dependent and inaccurate, and therefore completely uninteresting. We also argue that an accurate determination of f^2 using pp forward dispersion relations is not a realistic option.Comment: 19 pages, latex2e with a4wide.sty, more information is available at http://NN-OnLine.sci.kun.nl . Invited talk at FBXV, Groningen, The Netherlands, July 22-26, 1997. Invited talk at MENU97, Vancouver, B.C., Canada, July 28 - August 1, 199

Partial-Wave Analyses of all Proton-Proton and Neutron-Proton Data Below 500 MeV

In 1993 the Nijmegen group published the results of energy-dependent partial-wave analyses (PWAs) of the nucleon-nucleon (NN) scattering data for laboratory kinetic energies below Tlab=350 MeV (PWA93). In this talk some general aspects, but also the newest developments on the Nijmegen NN PWAs are reported. We have almost finished a new energy-dependent PWA and will discuss some typical aspects of this new PWA; where it differs from PWA93, but also what future developments might be, or should be.Comment: Presentation at the 19th European Conference on Few-Body Problems in Physics, Groningen, The Netherlands, 23-27 August 2004. 4 pages REVTeX4, no figure

Zero sound in a single component fermion - Bose Einstein Condensate mixture

The resonant dynamics of mediated interactions supports zero-sound in a cold atom degenerate mixture of a single component fermion gas and a Bose-Einstein condensate (BEC). We characterize the onset of instability in the phase separation of an unstable mixture and we find a rich collective mode structure for stable mixtures with one undamped mode that exhibits an avoided crossing and a Landau-damped mode that terminates.Comment: 4 pages, 2 figure

The evolutionary genetics of highly divergent alleles of the mimicry locus in Papilio dardanus

Background: The phylogenetic history of genes underlying phenotypic diversity can offer insight into the evolutionary origin of adaptive traits. This is especially true where single genes have large phenotypic effects, for example in determining polymorphic mimicry in butterflies. Here, we characterise the evolutionary history of two candidate genes for the mimicry switch in the polymorphic Batesian mimic Papilio dardanus coding for the transcription factors engrailed and invected. Results: We show that phased haplotypes associated with the dominant morphs f. poultoni and f. planemoides are phylogenetically highly divergent, in particular at non-synonymous sites. Some non-synonymous changes are shared between the divergent alleles suggesting either convergence or a shared ancestry. Gene trees for invected do not show this pattern. Despite their great divergence, all engrailed alleles of P. dardanus were monophyletic with respect to alleles of closely related species. Phylogenetic analyses therefore reveal no evidence for introgression from other species. A McDonald-Kreitman test conducted on a population sample from South Africa confirms a significant excess of intraspecific non-synonymous diversity in P. dardanus engrailed, suggesting long-term balanced polymorphism at this locus. Conclusions: The divergence between engrailed haplotypes suggests an evolutionary history distorted by selection with multiple changes reflecting recurrent selective sweeps. The high level of intraspecific polymorphism observed is characteristic of balancing selection on this locus, as expected if the gene engrailed is under phenotypic selection for the maintenance of multiple mimetic morphs. Non-synonymous changes in key functional portions of a major transcription factor are likely to be deleterious but if maintained in a dominant allele at low frequency, heterozygosity would reduce the associated genetic load

Degenerate fermion gas heating by hole creation

Loss processes that remove particles from an atom trap leave holes behind in the single particle distribution if the trapped gas is a degenerate fermion system. The appearance of holes increases the temperature and we show that the heating is (i) significant if the initial temperature is well below the Fermi temperature $T_{F}$, and (ii) increases the temperature to $T \geq T_{F}/4$ after half of the system's lifetime, regardless of the initial temperature. The hole heating has important consequences for the prospect of observing Cooper-pairing in atom traps.Comment: to be published in PR

Exploring the causes of adverse events in hospitals and potential prevention strategies

Objectives To examine the causes of adverse events (AEs) and potential prevention strategies to minimise the occurrence of AEs in hospitalised patients. Methods For the 744 AEs identified in the patient record review study in 21 Dutch hospitals, trained reviewers were asked to select all causal factors that contributed to the AE. The results were analysed together with data on preventability and consequences of AEs. In addition, the reviewers selected one or more prevention strategies for each preventable AE. The recommended prevention strategies were analysed together with four general causal categories: technical, human, organisational and patient-related factors. Results Human causes were predominantly involved in the causation of AEs (in 61% of the AEs), 61% of those being preventable and 13% leading to permanent disability. In 39% of the AEs, patient-related factors were involved, in 14% organisational factors and in 4% technical factors. Organisational causes contributed relatively often to preventable AEs (93%) and AEs resulting in permanent disability (20%). Recommended strategies to prevent AEs were quality assurance/peer review, evaluation of safety behaviour, training and procedures. For the AEs with human and patient-related causes, reviewers predominantly recommended quality assurance/peer review. AEs caused by organisational factors were considered preventable by improving procedures. Discussion Healthcare interventions directed at human causes are recommended because these play a large role in AE causation. In addition, it seems worthwhile to direct interventions on organisational causes because the AEs they cause are nearly always believed to be preventable. Organisational factors are thus relatively easy to tackle. Future research designs should allow researchers to interview healthcare providers that were involved in the event, as an additional source of information on contributing factors.

Schiff Theorem and the Electric Dipole Moments of Hydrogen-Like Atoms

The Schiff theorem is revisited in this work and the residual $P$- and $T$-odd electron--nucleus interaction, after the shielding takes effect, is completely specified. An application is made to the electric dipole moments of hydrogen-like atoms, whose qualitative features and systematics have important implication for realistic paramagnetic atoms.Comment: 3 pages. Contribution to PANIC05, Particles and Nuclei International Conference, Santa Fe, New Mexico, Oct. 24-28, 200

Are track recommendations dependent on schools and school boards? A study of trends in the level of track recommendations, number of double recommendations and reconsiderations in Dutch urban and rural areas

Track recommendations provided to students in the final grade of primary education lead the allocation to specific school tracks in secondary education in the Netherlands. Where the results of a standardised test indicate that students are able to go to a higher track level, primary schools are required to reconsider and potentially adjust the track recommendation to a higher level. The current research aimed to (1) investigate trends in the level of track recommendations, double track recommendations and reconsiderations over the years 2014–2015 to 2018–2019, (2) explore the variation in (trends of) track recommendations between Dutch primary schools and their school boards, and (3) assess the association between track recommendations and the school level variables degree of urbanisation and type of primary education. We used multilevel growth curve modelling for continuous and count data based on publicly available school-level population data regarding track recommendations and school leavers tests from 2014–2015 to 2018–2019. The number of double track recommendations has increased over the cohorts, with a slightly decreasing gap between schools in rural and urban areas. The number of reconsiderations first decreased and then increased. The differences in reconsiderations between rural and urban areas are increasing over time. An initial trend towards higher average recommendations stabilising in the later cohorts appeared with no clear pattern for degree of urbanisation. The current study adds to the existing knowledge by assessing longitudinal trends instead of cross-sectional analyses and including multiple stakeholders and factors simultaneously.</p

Intraspecific genetic variation in complex assemblages from mitochondrial metagenomics: comparison with DNA barcodes

Metagenomic shotgun sequencing, using Illumina technology, and de novo genome assembly of mixed field-collected amples of invertebrates readily produce mitochondrial genome sequences, allowing rapid identification and quantification of species diversity. However, intraspecific genetic variability present in the specimen pools is lost during mitogenome assembly, which limits the utility of ‘mitochondrial metagenomics’ for studies of population diversity. 2. Using 10 natural communities (>2600 individuals) of leaf beetles (Chrysomelidae), DNA variation in the mitochondrial cox1-5’ ‘barcode’ was compared for Sanger sequenced individuals and Illumina shotgun sequenced specimen pools. 3. Generally, only a single mitochondrial contig was assembled per species, even in the presence of intraspecific variation. Ignoring ambiguity from the use of two different assemblers, the cox1 barcode regions from these assemblies were exact nucleotide matches of a Sanger sequenced barcode in 90.7% of cases, which dropped to 76.0% in assemblies from samples with large intra and interspecific variability. Nucleotide differences between barcodes from both data types were almost exclusively in synonymous 3rd codon position, although the number of affected sites was very low, and the greatest discrepancies were correlated with poor quality of Sanger sequences. 4. Unassembled shotgun reads were also used to score single nucleotide polymorphisms and to calculate intraspecific nucleotide diversity (pi) for all available populations at each site. These values correlated with Sanger sequenced cox1 variation but were significantly higher. 5. Overall, the assemblage-focused shotgun sequencing of pooled samples produced nucleotide variation data comparable to the well-established specimen-focused Sanger approach. The findings thus extend the application of mitochondrial metagenomics of complex biodiversity samples to the estimation of diversity below the species level

Cosmic rays studied with a hybrid high school detector array

The LORUN/NAHSA system is a pathfinder for hybrid cosmic ray research combined with education and outreach in the field of astro-particle physics. Particle detectors and radio antennae were mainly setup by students and placed on public buildings. After fully digital data acquisition, coincidence detections were selected. Three candidate events confirmed a working prototype, which can be multiplied to extend further particle detector arrays on high schools.Comment: 10 pages, 6 figures. Nigl, A., Timmermans, C., Schellart, P., Kuijpers, J., Falcke, H., Horneffer, A., de Vos, C. M., Koopman, Y., Pepping, H. J., Schoonderbeek, G., Cosmic rays studied with a hybrid high school detector array, Europhysics News (EPN), Vol. 38, No. 5, accepted on 22/08/200