372 research outputs found
Pseudospin symmetry and its approximation in real nuclei
The origin of pseudospin symmetry and its broken in real nuclei are discussed
in the relativistic mean field theory. In the exact pseudospin symmetry, even
the usual intruder orbits have degenerate partners. In real nuclei, pseudospin
symmetry is approximate, and the partners of the usual intruder orbits will
disappear. The difference is mainly due to the pseudo spin-orbit potential and
the transition between them is discussed in details. The contribution of
pseudospin-orbit potential for intruder orbits is quite large, compared with
that for pseudospin doublets. The disappearance of the pseudospin partner for
the intruder orbit can be understood from the properties of its wave function.Comment: 10 pages, 3 figure
Multiobjective Design of Turbo Injection Mode for Axial Flux Motor in Plastic Injection Molding Machine by Particle Swarm Optimization
This paper proposes a turbo injection mode (TIM) for an axial flux motor to apply onto injection molding machine. Since the injection molding machine requires different speed and force parameters setting when finishing a complete injection process. The interleaved winding structure in the motor provides two different injection levels to provide enough injection forces. Two wye-wye windings are designed to switch two control modes conveniently. Wye-wye configuration is used to switch two force levels for the motor. When only one set of wye-winding is energized, field weakening function is achieved. Both of the torque and speed increase under field weakening operation. To achieve two control objectives for torque and speed of the motor, fuzzy based multiple performance characteristics index (MPCI) with particle swarm optimization (PSO) is used to find out the multiobjective optimal design solution. Both of the torque and speed are expected to be maximal at the same time. Three control factors are selected as studied factors: winding diameter, winding type, and air-gap. Experimental results show that both of the torque and speed increase under the optimal condition. This will provide enough large torque and speed to perform the turbo injection mode in injection process for the injection molding machine
Are AlphaZero-like Agents Robust to Adversarial Perturbations?
The success of AlphaZero (AZ) has demonstrated that neural-network-based Go
AIs can surpass human performance by a large margin. Given that the state space
of Go is extremely large and a human player can play the game from any legal
state, we ask whether adversarial states exist for Go AIs that may lead them to
play surprisingly wrong actions. In this paper, we first extend the concept of
adversarial examples to the game of Go: we generate perturbed states that are
``semantically'' equivalent to the original state by adding meaningless moves
to the game, and an adversarial state is a perturbed state leading to an
undoubtedly inferior action that is obvious even for Go beginners. However,
searching the adversarial state is challenging due to the large, discrete, and
non-differentiable search space. To tackle this challenge, we develop the first
adversarial attack on Go AIs that can efficiently search for adversarial states
by strategically reducing the search space. This method can also be extended to
other board games such as NoGo. Experimentally, we show that the actions taken
by both Policy-Value neural network (PV-NN) and Monte Carlo tree search (MCTS)
can be misled by adding one or two meaningless stones; for example, on 58\% of
the AlphaGo Zero self-play games, our method can make the widely used KataGo
agent with 50 simulations of MCTS plays a losing action by adding two
meaningless stones. We additionally evaluated the adversarial examples found by
our algorithm with amateur human Go players and 90\% of examples indeed lead
the Go agent to play an obviously inferior action. Our code is available at
\url{https://PaperCode.cc/GoAttack}.Comment: Accepted by Neurips 202
Treatment of critically sized femoral defects with recombinant BMP-2 delivered by a modified mPEG-PLGA biodegradable thermosensitive hydrogel
Homogenization of Halide Distribution and Carrier Dynamics in Alloyed Organic-Inorganic Perovskites
Perovskite solar cells have shown remarkable efficiencies beyond 22%, through
organic and inorganic cation alloying. However, the role of alkali-metal
cations is not well-understood. By using synchrotron-based nano-X-ray
fluorescence and complementary measurements, we show that when adding RbI
and/or CsI the halide distribution becomes homogenous. This homogenization
translates into long-lived charge carrier decays, spatially homogenous carrier
dynamics visualized by ultrafast microscopy, as well as improved photovoltaic
device performance. We find that Rb and K phase-segregate in highly
concentrated aggregates. Synchrotron-based X-ray-beam-induced current and
electron-beam-induced current of solar cells show that Rb clusters do not
contribute to the current and are recombination active. Our findings bring
light to the beneficial effects of alkali metal halides in perovskites, and
point at areas of weakness in the elemental composition of these complex
perovskites, paving the way to improved performance in this rapidly growing
family of materials for solar cell applications.Comment: updated author metadat
Complete chloroplast genome sequence of Holoparasite Cistanche Deserticola (Orobanchaceae) reveals gene loss and horizontal gene transfer from Its host Haloxylon Ammodendron (Chenopodiaceae)
The central function of chloroplasts is to carry out photosynthesis, and its gene content and structure are highly conserved across land plants. Parasitic plants, which have reduced photosynthetic ability, suffer gene losses from the chloroplast (cp) genome accompanied by the relaxation of selective constraints. Compared with the rapid rise in the number of cp genome sequences of photosynthetic organisms, there are limited data sets from parasitic plants. The authors report the complete sequence of the cp genome of Cistanche deserticola, a holoparasitic desert species belonging to the family Orobanchaceae
Determination of HER2 status using both serum HER2 levels and circulating tumor cells in patients with recurrent breast cancer whose primary tumor was HER2 negative or of unknown HER2 status
Exercise and manual auricular acupuncture: a pilot assessor-blind randomised controlled trial. (The acupuncture and personalised exercise programme (APEP) Trial)
<p>Abstract</p> <p>Background</p> <p>Evidence supports the use of exercise for chronic low back pain (CLBP); however, adherence is often poor due to ongoing pain. Auricular acupuncture is a form of pain relief involving the stimulation of points on the outer ear corresponding with specific body parts. It may be a useful adjunct to exercise in managing CLBP; however, there is only limited evidence to support its use with this patient group.</p> <p>Methods/Design</p> <p>This study was designed to test the feasibility of an assessor-blind randomised controlled trial which assess the effects on clinical outcomes and exercise adherence of adding manual auricular acupuncture to a personalised and supervised exercise programme (PEP) for CLBP. No sample size calculation has been carried out as this study aims to identify CLBP referral rates within the catchment area of the study site. The researchers aim to recruit four cohorts of n = 20 participants to facilitate a power analysis for a future randomised controlled trial. A computer generated random allocation sequence will be prepared centrally and used to allocate participants by cohort to one of the following interventions: 1) six weeks of PEP <it>plus </it>manual auricular acupuncture; 2) six weeks of PEP alone. Both groups will also complete a further six weeks of self-paced exercise with telephone follow-up support. In addition to a baseline and exit questionnaire at the beginning and end of the study, the following outcomes will be collected at baseline, and after 7, 13 and 25 weeks: pain frequency and bothersomeness, back-specific function, objective assessment and recall of physical activity, use of analgesia, perceived self-efficacy, fear avoidance beliefs, and beliefs about the consequences of back pain. Since this is a feasibility study, significance tests will not be presented, and treatment effects will be represented by point estimates and confidence intervals. For each outcome variable, analysis of covariance will be performed on the data, conditioning on the baseline value.</p> <p>Discussion</p> <p>The results of this study investigating the adjuvant effects of auricular acupuncture to exercise in managing CLBP will be used to inform the design of a future multi-centre randomised controlled trial.</p> <p>Trial Registration</p> <p>Current Controlled Trials ISRCTN94142364.</p
Perioperative celecoxib administration for pain management after total knee arthroplasty – A randomized, controlled study
<p>Abstract</p> <p>Background</p> <p>Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended for multimodal postoperative pain management. We evaluated opioid-sparing effects and rehabilitative results after perioperative celecoxib administration for total knee arthroplasty.</p> <p>Methods</p> <p>This was a prospective, randomized, observer-blind control study. Eighty patients that underwent total knee arthroplasty were randomized into two groups of 40 each. The study group received a single 400 mg dose of celecoxib, one hour before surgery, and 200 mg of celecoxib every 12 hours for five days, along with patient-controlled analgesic (PCA) morphine. The control group received only PCA morphine for postoperative pain management. Visual analog scale (VAS) pain scores, active range of motion (ROM), total opioid use and postoperative nausea/vomiting were analyzed.</p> <p>Results</p> <p>Groups were comparable for age, pre-operative ROM, operation duration and intraoperative blood loss. Resting VAS pain scores improved significantly in the celecoxib group, compared with controls, at 48 hrs (2.13 ± 1.68 vs. 3.43 ± 1.50, p = 0.03) and 72 hrs (1.78 ± 1.66 vs. 3.17 ± 2.01, p = 0.02) after surgery. Active ROM also increased significantly in the patients that received celecoxib, especially in the first 72 hrs [40.8° ± 17.3° vs. 25.8° ± 11.5°, p = 0.01 (day 1); 60.7° ± 18.1° vs. 45.0° ± 17.3°, p = 0.004 (day 2); 77.7° ± 15.1° vs. 64.3° ± 16.9°, p = 0.004 (day 3)]. Opioid requirements decreased about 40% (p = 0.03) in the celecoxib group. Although patients suffering from post-operative nausea/vomiting decreased from 43% in control group to 28% in celecoxib group, this was not significant (p = 0.57). There were no differences in blood loss (intra- and postoperative) between the groups. Celecoxib resulted in no significant increase in the need for blood transfusions.</p> <p>Conclusion</p> <p>Perioperative celecoxib significantly improved postoperative resting pain scores at 48 and 72 hrs, opioid consumption, and active ROM in the first three days after total knee arthroplasty, without increasing the risks of bleeding.</p> <p>Trial registration</p> <p>Clinicaltrials.gov NCT00598234</p
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