High-z radio starbursts host obscured X-ray AGN

We use Virtual Observatory methods to investigate the association between radio and X-ray emission at high redshifts. Fifty-five of the 92 HDF(N) sources resolved by combining MERLIN+VLA data were detected by Chandra, of which 18 are hard enough and bright enough to be obscured AGN. The high-z population of microJy radio sources is dominated by starbursts an order of magnitude more active and more extended than any found at z<1 and at least a quarter of these simultaneously host highly X-ray-luminous obscured AGN.Comment: 4 pages, 2 figures, To appear in the proceedings of 'At the Edge of the Universe' (9-13 October 2006, Sintra, Portugal

Starburst Galaxies

Star-formation and the Starburst phenomenon are presented with respect to a number of nearby star-forming galaxies where our understanding of the process can be calibrated. Methods of estimating star-formation rates are discussed together with the role played in the investigation of the process by multi-wavelength studies of a few selected starburst galaxies (especially the well studied galaxy M82). Our understanding of nearby systems allows us to study the star-formation history of the Universe by observing high-redshift starburst galaxies. These begin to dominate the radio source populations at centimetric wavelengths at flux densities below a few 10s of Jy. New very sensitive, high resolution telescopes in the sub-mm and radio will revolutionize our understanding of these distant star-forming systems, some of which may contain embedded AGN.Comment: 15 pages, 19 figures, To appear in the proceedings of `The 8th European VLBI Network Symposium on New Developments in VLBI Science and Technology', ed. A. Marecki et al., held in Torun, Poland, on September 26-29, 2006 (Invited Review

An evolution of the IR-Radio correlation?

Using extremely deep (rms 3.3 microJy/bm) 1.4GHz sub-arcsecond resolution MERLIN + VLA radio observations of a 8'.5 by 8'.5 field centred upon the Hubble Deep Field North, in conjunction with Spitzer 24 micron data we present an investigation of the radio-MIR correlation at very low flux densities. By stacking individual sources within these data we are able to extend the MIR-radio correlation to the extremely faint (~microJy and even sub-microJy) radio source population. Tentatively we demonstrate a small deviation from the correlation for the faintest MIR sources. We suggest that this small observed change in the gradient of the correlation is the result of a suppression of the MIR emission in faint star-forming galaxies. This deviation potentially has significant implications for using either the MIR or non-thermal radio emission as a star-formation tracer at low luminosities.Comment: To Appear in The Modern Radio Universe: From Planets to Dark Energy Conference (Oct 1-5 2007, The University of Manchester) Editors: Beswick, Diamond & Schilizz

Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma

Bromelain, a widely used pineapple extract with cysteine protease activity, has been shown to have immunomodulatory effects in a variety of immune system models. The purpose of the present study was to determine the effects of orally administered bromelain in an ovalbumin (OVA)-induced murine model of acute allergic airway disease (AAD). To establish AAD, female C57BL/6J mice were sensitized with intraperitoneal (i.p.) OVA/alum and then challenged with OVA aerosols for 3 days. Mice were gavaged with either (phosphate buffered saline)PBS or 200 mg/kg bromelain in PBS, twice daily for four consecutive days, beginning 1 day prior to OVA aerosol challenge. Airway reactivity and methacholine sensitivity, bronchoalveolar lavage (BAL) cellular differential, Th2 cytokines IL-5 and IL-13, and lung histology were compared between treatment groups. Oral bromelain-treatment of AAD mice demonstrated therapeutic efficacy as evidenced by decreased methacholine sensitivity (P ≤ 0.01), reduction in BAL eosinophils (P ≤ 0.02) and IL-13 concentrations (P ≤ 0.04) as compared with PBS controls. In addition, oral bromelain significantly reduced BAL CD19+ B cells (P ≤ 0.0001) and CD8+ T cells (P ≤ 0.0001) in AAD mice when compared with controls. These results suggest that oral treatment with bromelain had a beneficial therapeutic effect in this murine model of asthma and bromelain may also be effective in human conditions

Socially sensitive lactation: Exploring the social context of breastfeeding

Many women report difficulties with breastfeeding and do not maintain the practice for as long as intended. Although psychologists and other researchers have explored some of the difficulties they experience, fuller exploration of the relational contexts in which breastfeeding takes place is warranted to enable more in-depth analysis of the challenges these pose for breastfeeding women. The present paper is based on qualitative data collected from 22 first-time breastfeeding mothers through two phases of interviews and audio-diaries which explored how the participants experienced their relationships with significant others and the wider social context of breastfeeding in the first five weeks postpartum. Using a thematic analysis informed by symbolic interactionism, we develop the overarching theme of ‘Practising socially sensitive lactation’ which captures how participants felt the need to manage tensions between breastfeeding and their perceptions of the needs, expectations and comfort of others. We argue that breastfeeding remains a problematic social act, despite its agreed importance for child health. Whilst acknowledging the limitations of our sample and analytic approach, we suggest ways in which perinatal and public health interventions can take more effective account of the social challenges of breastfeeding in order to facilitate the health and psychological well-being of mothers and their infants