Botanists Jenny Winham standing left, and Patricia Selkirt collecting plant samples on Heard Island, Antarctica, October 2000 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Reproduction of: 1 transparency : col.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010

Dr Martin Truffer passing ice core samples to glaciologist Shavawn Donoghue, Brown Glacier, Heard Island, Antarctica, January 2004 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010

Research ship Southern Supporter carrying poly water tanks, and view of Laurens Peninsula in the background, near Atlas Cove, Heard Island, Antarctica, December 2003 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010. "Research ship 'Southern Supporter' near Atlas Cove, Heard Island. The upper deck is crowded with modified plastic water tanks, which are to be used for accomodation ashore by research scientists visiting for the 2003-04 summer. Two LARCS can be seen on the trawl deck. Laurens Peninsula in the background, December 2003"--Information supplied by photographer

Light amphibious resupply cargo vessel transporting gear with Stephenson Glacier in background, Heard Island, Antarctica, February 2004 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010. "Light Amphibious Resupply Craft (LARC) being used to retrieve gear from Spit Bay Camp. In the background is Stephenson Lagoon, with Stephenson Glacier flowing down the NE flank of Big Ben, February 2004"--Information supplied by photographer

Glaciologist student Shavawn Donoghue sampling an ice core taken from Brown Glacier, Heard Island, Antarctica, January 2004 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010. "PhD student Shavawn Donoghue (University of Tasmania) sectioning and sampling an ice core. Brown Glacier, Heard Island January 2004"--Information supplied by photographer

Scientists measuring albedo effect off sea ice with a pyranometer, Antarctica, November ca. 1988 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Reproduction of: 1 transparency : col.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010. Scientists suspended in a man cage from a crane on the German flagged ship 'Icebird'. Voyage 1.1. with the Australian National Antarctic Research Expedition (ANARE), circa November 1988--Information supplied by photographer

CASA 212-400 Aviocar transport aircraft at Casey Station Skiway, Antarctica, December 2005 [picture] /

Title devised by cataloguer based on information from acquisitions documentation.; Part of the collection: Scientific activities at Heard Island and Antarctica.; Acquired in digital format; access copy available online.; Mode of access: Internet via World Wide Web.; Purchased from the photographer 2010

Contrasting P-T-t paths for neoproterozoic metamorphism in MacRobertson and Kemp lands, east Antarctica

The definitive version is available at www.blackwell-synergy.comMineral equilibria modelling and electron microprobe chemical dating of monazite in granulite facies metapelitic assemblages from the MacRobertson Land coastline, Rayner Complex, east Antarctica, are consistent with an ‘anticlockwise’ Neoproterozoic P–T–t path. Metamorphism occurred at c. 990–970 Ma, achieving peak conditions of 850 °C and 5.6–6.2 kbar at Cape Bruce, and 900 °C and 5.4–6.2 kbar at the Forbes Glacier 50 km to the east. These peak metamorphic conditions preceded the emplacement of regionally extensive syntectonic charnockite. High temperature conditions are likely to have been sustained for 80 Myr by lithospheric thinning and repeated pluton emplacement; advection was accompanied by crustal thickening to maximum pressures of 6–7 kbar, followed by near-isobaric cooling. This P–T–t path is distinct from that of rocks in adjacent Kemp Land, 50 km to the west, where a ‘clockwise’ P–T–t path from higher-P conditions at c. 940 Ma may reflect the response of a cratonic margin displaced from the main magma flux. In this scenario, crustal shortening was initially accommodated in younger, fertile crust (MacRobertson Land) involving metasediments and felsic plutons with the transfer of strain to adjacent older crust (Kemp Land) subsequent to charnockite emplacement.J. A. Halpin, G. L. Clarke, R. W. White, D. E. Kelse

Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1

The mitochondrial chaperone mortalin was implicated in Parkinson's disease (PD) because of its reduced levels in the brains of PD patients and disease-associated rare genetic variants that failed to rescue impaired mitochondrial integrity in cellular knockdown models. To uncover the molecular mechanisms underlying mortalin-related neurodegeneration, we dissected the cellular surveillance mechanisms related to mitochondrial quality control, defined the effects of reduced mortalin function at the molecular and cellular levels and investigated the functional interaction of mortalin with Parkin and PINK1, two PD-related proteins involved in mitochondrial homeostasis. We found that reduced mortalin function leads to: (1) activation of the mitochondrial unfolded protein response (UPR(mt)), (2) increased susceptibility towards intramitochondrial proteolytic stress, (3) increased autophagic degradation of fragmented mitochondria and (4) reduced mitochondrial mass in human cells in vitro and ex vivo. These alterations caused increased vulnerability toward apoptotic cell death. Proteotoxic perturbations induced by either partial loss of mortalin or chemical induction were rescued by complementation with native mortalin, but not disease-associated mortalin variants, and were independent of the integrity of autophagic pathways. However, Parkin and PINK1 rescued loss of mortalin phenotypes via increased lysosomal-mediated mitochondrial clearance and required intact autophagic machinery. Our results on loss of mortalin function reveal a direct link between impaired mitochondrial proteostasis, UPR(mt) and PD and show that effective removal of dysfunctional mitochondria via either genetic (PINK1 and Parkin overexpression) or pharmacological intervention (rapamycin) may compensate mitochondrial phenotypes